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How to use Growth Hormone????

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It's been 2 years since I last used gear. The reason why I don't use it anymore is because I think I'm fairly big enough for my height. Not only that but I have very small joints which means I don't need to pack on that much to look big. Not only that but I haven't been able to get my hands on anything good anymore. The stuff that I get is either underdosed, fake or just plain makes me sick! What I do use now is growth hormone. Not fake stuff...but the real deal from the pharmacy. I've been taking 6iu's everyday for the last year and a half. I take 3iu's before bed and upon waking up. I don't know if this is the correct way but a lot of people have told me to do it like this. From taking nothing but the GH, I have slept better, been happier, and have had a bit more energy. The only problem is that I'm not losing fat like the way GH is all hyped on! When I started taking it late last year, I was at 10%bf. Now after over a year I'm at 8%bf. I can't seem to lose anymore! I'm eating clean, lifting for 90 minutes at the gym and then jogging for 30minutes. Then I work at textile factory that requires more strenous physical work. I'm not getting fatter, but I'm just not getting leaner at all! I've heard of people taking GH and eating everything in site and shedding fat. How come it's not happening to me?? What I'm I doing wrong?? Any suggestion s and/or advice would be greatly appreciated. Thank you!
 
how old are u???

u shouldnt be takin it b4 bed...

ur body will natually be producing growth once u get into REM and u dnt want to fuck that up
 
gilly...I never said I was going to eat everything in site. This is just what I have seen and heard of others that have been taking GH. Anointed....I am 29 years old.
 
You've been on 6iu ED for a year and a half? I sure hope you have been avoiding carbs. I also remember DrJMW stating that continued use of exo-GH will result in hypothyroidism so you need to use Armour or T3 along with it. I'm not sure what the mechanism would be though. Thyroid hormone does stimulate GH secretion, and at the same time GH replacement is known to increase the rate of T4 to T3 conversion so maybe the increased T3 results in the eventual decline in TSH?
 
well....I've been on GH for about a year now and sure don't avoid carbs.....are those studies on healthy 30 year old adults....probably not
 
gilly6993 said:
well....I've been on GH for about a year now and sure don't avoid carbs.....are those studies on healthy 30 year old adults....probably not
Click to expand...

No, the first was on a GH deficient adults that were put on low dose GH therapy and the second was on not well children. There are other studies, but I doubt many of them address 30 healthy adults or people using 3x what a normal human would produce.

If the mode of action is as the study states, ie: the mobilization of fatty acids and a shift towards insulin-resistant type II muscle fibers, then I don't see what being healty a healthy 30yo adult is going to accomplish.
 
Not sure if this helps much (just confuses me):

http://diabetes.diabetesjournals.org/cgi/content/abstract/50/8/1891

These results indicate that cellular insulin resistance induced by chronic GH treatment in 3T3-L1 adipocytes is caused by uncoupling between activation of PI 3-kinase and its downstream signals, which is specific to the insulin-stimulated PI 3-kinase pathway. This effect of GH might result from the altered subcellular distribution of IRS-1–associated PI 3-kinase.

and...

http://www.ebmonline.org/cgi/content/abstract/227/3/149

long-term exposure to GH is, in general, associated with hyperinsulinemia, which leads to a reduction of IR levels and an impairment of its tyrosine kinase activity. The signals of GH and insulin may converge at post-receptor levels. The signaling pathway leading to activation of PI 3-kinase appears to be an important site of convergence between the signals of these two hormones and seems to be mediated principally by IRS-1. Rodent models of chronic GH excess have been useful tools to investigate the mechanism by which GH induces insulin resistance. Decreased IR, IRS-1, and IRS-2 tyrosyl phosphorylation in response to insulin was found in skeletal muscle, whereas a chronic activation of the IRS-PI 3-kinase pathway was found in liver. The induction of the expression of proteins that inhibit IR signaling such as suppressors of cytokine signaling (SOCS)-1 and -6 may also be involved in this alteration.
 
Not sure if anyone's actually interested in the risks of insulin resistance caused by exo-GH, but I've got another question along these lines.

Assuming the insulin resistance results from the mechanisims in my post above (fatty acid mobilization and shift towards insulin-resistant type II muscle fibers), then wouldn't someone with low or very low total bodyfat offset at least some of those risks?
 
I am very confused here. So taking GH will get me fat??? Because of Insulin?? What??!!! I thought GH was supposed to make you shed fat like no other drug!? Whats going on. Please...speak english. So too much GH will make me fat?? Avoid carbs?? Take less GH??? Please, I need help and I don't understand anybody.
 
Carth said:
I am very confused here. So taking GH will get me fat??? Because of Insulin?? What??!!! I thought GH was supposed to make you shed fat like no other drug!? Whats going on. Please...speak english. So too much GH will make me fat?? Avoid carbs?? Take less GH??? Please, I need help and I don't understand anybody.
Click to expand...

Okay this is my understanding in simplest possible terms, and it's probably far from perfect...

GH frees up fatty acids from your fat cells which is good for shrinking them and making you less fat. Insulin transports fat and glucose around your body. If lots of fattty acids are floating around then your insulin is going to be working to move that around instead of glucose (which comes from your carbs). GH also favors insulin resistant muscle tissue, which wont be too good for helping bring down high insulin or glucose levels.

GH definitely causes an increase in the rate at which T4 is converted to T3 which is good for increased metabolism (up to 10% in one study) which means less fat, but over time that might mean you pituitary will put out less TSH which could lead to less T4 and therefore less T3 and thus eventually lower metabolism and less fat burning. So...you can add T3 to offset this decrease. (I am less sure about this last paragraph).

So...anyhow IMO if you are on GH you should restrict carbs to something low but reasonable (less than 100g a day?) and possibly include T3 or armour to offset and any throid "sluggishness" that might result. The big question in my head is: what is the risk of insulin resistance in very low fat individuals? If part of the problem stems from the fact that GH favors lipid mobilization, well if there are very few lipids to mobilize then I would think the problem is mitigated.
 
So GH is NOT a miracle drug? I should stop taking it because it will make me fat? 100grams of carbs of day???? No way! And GH lowers T3? So that means that all the pros take GH and thyroid hormones all year round? Bottom line...should I stop the GH then?
 
So GH is NOT a miracle drug?
No, it definitely isn't.

I should stop taking it because it will make me fat?
Nope, didn't say anything like that.

100grams of carbs of day???? No way!
If insulin resistance is real and you insist on running GH for long periods of time and insist on eating significant amounts of carbs you may be doing yourself real harm. But, whatever...

And GH lowers T3?
That's speculation on my part. I know DrJMW recommends that GH be used along with some form of thyroid med as it GH eventually results in thyroid sluggishness. Do a search on DRJMW and GH.

So that means that all the pros take GH and thyroid hormones all year round?
I have no idea what they do. Are you a pro?


Bottom line...should I stop the GH then?
That's your decision. If I had been using it for 18 months and 6iu ED and hadn't seen any body composition changes I would certainly drop it. Can't imagin the $12 (at least?) you are spending each day really seems to be money well spent.
 
100grams of carbs of day???? No way!
If insulin resistance is real and you insist on running GH for long periods of time and insist on eating significant amounts of carbs you may be doing yourself real harm. But, whatever...


Harm how??? Why exactly?? Eating carbs and GH is wrong?! I need more clarification on this.
 
 
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