How exactly does Marijuana affect memory?

[Whiskey]

puff puff pass bro, puff puff pass!! did you forget already!?!

Whiskey

 

[juiceddreadlocks]

Marijuana seems to selectively inhibit short term memory formation in chronic users probably through an anti-cholinergic mechanism. However one paper found neuron death in the hippocampus in vitro due to direct exposure to THC. The hippocampus is a structure in the brain which is directly related to short term memory formation

The Journal of Neuroscience, July 15, 1998, 18(14):5322-5332


Hippocampal Neurotoxicity of 9-Tetrahydrocannabinol
Guy Chiu-Kai Chan, Thomas R. Hinds, Soren Impey, and Daniel R. Storm
Department of Pharmacology, University of Washington, Seattle, Washington 98195


AND


Short-term memory impairment in cannabis-dependent adolescents
R. H. Schwartz, P. J. Gruenewald, M. Klitzner and P. Fedio
Department of Pediatrics, Georgetown University School of Medicine, Washington, DC.

good post, the hippocampus is involved with short term memory storage (especially declarative)

THC may act on CBR1 receptors which are the most powerful G protein coupled receptors we've discovered as of yet. G receptors can have some wicked second messenger effects, and so on...

hooray for the limbic system!

 

[BrothaBill]

good post, the hippocampus is involved with short term memory storage (especially procedural)

THC may act on CBR1 receptors which are the most powerful G protein coupled receptors we've discovered as of yet. G receptors can have some wicked second messenger effects, and so on...

WRONG, geesh reefer madness again

 

[UA_Iron]

I used to get high and drive around town blasting SLAYER

ah good times.

I prefer uppers over downers though. I havent smoked weed in like 2 years

 

[bdog527]

good post, the hippocampus is involved with short term memory storage (especially declarative)

THC may act on CBR1 receptors which are the most powerful G protein coupled receptors we've discovered as of yet. G receptors can have some wicked second messenger effects, and so on...

hooray for the limbic system!

Sanofi-Aventis has a CBR1 antagonist in the works for weight loss. The studies they have done have been promising.

 

[juiceddreadlocks]

Sanofi-Aventis has a CBR1 antagonist in the works for weight loss. The few studies they have done have been promising.

hey do you have a link for that?!?

 

[Ulcasterdropout]

Smoke shit, straight from the roach clip...

 

[juiceddreadlocks]

WRONG, geesh reefer madness again

lol, i edited the procedural part out. i meant to put declarative.

 

[bdog527]

hey do you have a link for that?!?

http://www.drugdevelopment-technology.com/projects/rimonabant/

 

[juiceddreadlocks]

http://www.drugdevelopment-technology.com/projects/rimonabant/

thanks, sounds cool.