For on-cycle support, keeping it simple and targeted works best: NAC (1200mg/day) for liver protection, Citrus Bergamot for lipid management, and Telmisartan or CoQ10 if blood pressure creeps up on heavy compounds.
Beyond OTC supplements, making sure your base gear isn't dirty or underdosed solves half the side-effect battle before it starts. I've been running my blasts and ancillaries from 10X Muscle (10xmuscle com / 10xmuscle pw)—smooth carrier oil, zero PIP, and lab work stays clean throughout the cycle.