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Glutamine Powder - Gold or Garbage?

Glutamine Powder - Garbage or Gold?

  • Gold

    Votes: 111 44.6%

  • Garbage

    Votes: 53 21.3%

  • I have no idea but enjoy excercising my right to have my voice heard, although my voice isn't really

    Votes: 85 34.1%
  • Total voters
    249
Synpax

Synpax

Well-known member
Post any evidence on either side. Trying to decide if it's a waste of my money or not.

Saw Spatts saying in large quantities it helps her with recovery, and others say it helps with Delayed onset muscle soreness.

Saw BodyByFinaplex say it's useless to ingest 30g or so a day.
 
Synpax said:
Post any evidence on either side. Trying to decide if it's a waste of my money or not.

Saw Spatts saying in large quantities it helps her with recovery, and others say it helps with Delayed onset muscle soreness.

Saw BodyByFinaplex say it's useless to ingest 30g or so a day.
Click to expand...

Spatts is using glutamine peptide (gplenish in particular) which is much more bioavailable. pure l-glutamine is of little use except at high doses, where it tends to cause gastric distress.
 
I actually disagree. FOr a month I took 5 mg L-gutamine post workout and 5mg before bed, and I had zero muscle soreness, and some nice pumps. I have been taking GPlenish 1 serving in the morning, 1 serving post workout, and 1 serving before bed for 4 weeks, and I feel maybe 50% less soreness, get a nice pump, and it may be helping to gain lean muscle. This may just be my personal outcome and other people get better results, but I definitely wouldn't say that glutamine peptides are any better then L-glutamine.
 
Bro....Peptides (gplenish) are A!! fucking amazing, if they were cheaper they would constitute 70% of my diet, but alas...



Omega when the 5lb version coming out :p :mad: ;)
 
L-glutamine sucks, I used the GNC brand for months and nothing. Then I switched to gplenish. Huge difference, nasty taste. Though you will get used to that and its worth it, and when you really think about how much glutamine is getting in your system this way, its really cheaper too.
 
Not sure about g-plenish or peptides, but regular glutamine is pretty much useless unless taken IV. I will post study tonite when I get home from school.
 
I currently use GNC's L-Glutamine 1000mg tabs. I take four of those -4000 mgs (or 4 gs) and get alot of cell volumization (pumps) from it and not that sore- even ater heavy workouts. Do get a little bloated though.
 
Try taking a high dose of l-glutamine powder some time when you feel a cold coming on. Then tell me if you think it's garbage or not.

Check out the thread on glutamine from Hucklberry Finaplex. It's some powerful stuff.

I definitely feel like it boosts my immune system and cuts the stress from heavy workouts.

Nukdae
 
I don’t know why but Glutamine seems to help me recover from a cold or the flu way faster. If you’re healthy you can train harder, but as for a bodybuilding supplement, I’ve only noticed a slight reduction in recovery time maybe after a hard leg day. At least it’s cheep now.
 
Ive noticed most of the same said here, slightly quicker recovery, and Ive noticed after trying to shed fat fast (masive cardio), i dont lose as much muscle. I will actually gain weight or stay the same weight for weeks, as I watch my BF decrease! Got luv that!

Deff intrested in this G-plenish though, can it be purchased any where besides EF???
any comproble brands???
 
glutamine is one of the most important amino acids. the only reason why its not an essential amino is because it is made in the body. glutamine makes up 60% of the amino acids in your muscles. after hard training your body drains the aminos out of your muscles and you need to restock them. your body cant produce enough glutamine in the time required to repair your muscles as soon as possible. this is why you need to suplement with glutamine. there are so many benifits to glutamine it would take me way too long to type it! there was a good article in 'Muscular Development' november 1996 called 'Glutamine Harness the Pomer' if you can find it you should read it. its very informative on glutamine.
 
I think one reason people are getting good results from glutamine peptides is their over reliance on whey protein as a protein source. Milk protein isolate has 37% more glutamine than whey protein and even though whey is touted as the worlds greatest source of BCAA's it only has 3% more BCAA's than milk isolate. Milk Isolate has 26% more glutamine than beef and 28% more than chicken breast. If someone consumed 200g of whey protein per day and switched to milk isolate that would be equivelant to adding roughly a serving and a half of ener-g/g-plenish to their diet.
 
so are you liking the ENER-G:)


also its not so simple as just take milk isolate or whatever Hydolisate may have more Glutamine tipped in its favor


the formation and composition of EnerG

shifts it to work and work excellent

even more so that other

'glutamine peptides'

EnerG is unique


I always say "try all others, try every form of glutamine then try EnerG......."
 
OMEGA said:
GOLD

glutamine peptides are GOLD!!!!!!!!!!!!!!!
Click to expand...

Yes , I've used you guy's energ because it's peptide bound. L-glutamine can't deal with the ph of your stomach so most of it does not survive. Yes l-glutamine has many benefits but you have to get it absorbed first :-)

The majority of commercially available Glutamine sources offer only L-Glutamine, a synthetic, free amino acid. L-Glutamine has been shown to be unstable in the presence of heat, water, acid or base solutions, making L-Glutamine impractical to utilize in all but powdered food preparations. Covalent Bonded Glutamine, on the other hand, has been shown to withstand processing temperatures of 180 degrees Fahrenheit for one hour or 250 degrees Fahrenheit for 15 minutes and pH variances in the range of 3.5 to 9.0.

In addition, Covalent Bonded Glutamine is stable in aqueous solutions for prolonged periods of time. Covalent Bonded Glutamine can be used in all liquid and semi-solid food preparations. In addition, due to the instability of L-Glutamine in water and pH extremes, it is safe to assume that much of L-Glutamine decomposes once it passes into the human gastrointestinal tract. Gastric acid is equivalent to 0.1 Normal Hydrochloric Acid (pH less than 2) and at 98.6 degrees Fahrenheit and a pH below 2, L-Glutamine decomposes very quickly.

Since L-Glutamine is a free amino acid, what percentage that does survive the pH extremes of the stomach is absorbed through the intestinal wall by a different mechanism than covalent bound amino acids...this free amino acid absorption mechanism is competitive... meaning that in an excess of free amino acids, only a certain percentage of any particular free amino acid will be absorbed.
 
Curious? Stomach acid plays a large part in deactivating the L-Glutamine. What then if I were to take a tums prior? Would that increase its availability, if so could anyone speculate as to how much?
 
gjohnson5 said:
Covalent Bonded Glutamine, on the other hand, has been shown to withstand processing temperatures of 180 degrees Fahrenheit for one hour or 250 degrees Fahrenheit for 15 minutes and pH variances in the range of 3.5 to 9.0.

Gastric acid is equivalent to 0.1 Normal Hydrochloric Acid (pH less than 2)
Click to expand...

Then glutamine peptides are about as useful as L-glutamine orally.
 
OMEGA said:
define "about"
Click to expand...

Well, there's enough studies out there now that have debunked L-glutamine. It's well know that supplement manufacturer's used intravenous studies of high-dose glutamine to fuel sales of oral L-glutamine.

The only thing that's keeping L-glutamine on store shelves is 1) Supplement companies pushing it, and 2) Anecdotal evidence.

'nuff said about that, since we've been through this before. But on to peptides.....

I was actually about to order some glutamine peptides from Trueproteincanada.com, to try for myself. Like I've said before, if peptides are actually able to do what l-glutaime can't, I'd be one happy camper, since I beat the shit outa my body weekly.

But it looks like the pH tolerance of glutamine peptides, while much better than L-glutamine, doesn't cut it in the stomach enviroment.
 
OMEGA said:
according to who?
Click to expand...

When food reaches the stomach, gastrin stimulates the secretion of hydrocholic acid, which lowers the pH of the stomach to about 1.5-1.7. At this low acidity, proteins denature, enabling stomach proteases to begin breaking apart peptide bonds.

According to human physiology. Hard to argue that one.
 
the peptides bonds begin to be brokern down, the glutamine that is cleaved pasess both through the stomach lining and the lumen of the intestine

thus much more glutamine is deliverd much like the rest of the aminos you consume form both solid and powdered protien forms........

the stomach is the first step in the digective process, not a black hole like you have pictured for us and would have us believe
 
Cauliflower Ear said:
i got a kilo of peptides...already feeling betterr recovery from it
Click to expand...

Let us know how long that placebo effect lasts. :FRlol:

On a serious note, I wish they'd find a way to quantify if glutamine works or not. Something like decreased CK-MB levels, or the equivalent, after consumption of glutamine....actually, come to think of it, if it did work like that, they'd be using glutamine in cardiac rehab.....bah, nevermind. Ramblings of a guy who's pre-workout formula is kicking in. Perhaps alpha-actin.
 
MikeMartial said:
Let us know how long that placebo effect lasts. :FRlol:
Click to expand...

:rolleyes:

you have not even tried G-covery so your Communist manifesto against glutamine peptides is moot

NO offense of course :)
 
OMEGA said:
:rolleyes:

you have not even tried G-covery so your Communist manifesto against glutamine peptides is moot

NO offense of course :)
Click to expand...

Hehe, no offense taken. ;)

In all seriousness, Omega, I did offer to test G-covery a long time ago, and report my findings back here. Like I said then, I'm the perfect candidate: I resistance train, I do HIIT, I train in two completely different martial arts (Muay Thai and No-gi jujitsu), I have a very physical job as firefighter/paramedic, and I do shiftwork. If anyone needs better recovery, it'd be me.

Offer still stands: You send me some G-covery, and I'll log my findings on EF.
 
Omega said:
the stomach is the first step in the digective process, not a black hole like you have pictured for us and would have us believe
Click to expand...

Actually, the mouth is the first step in the digestive process. This is covered in Biology101. But aside from that ...

Glutamine, whether as a free-form L-glutamine or as a peptide, does not and has not been shown to produce any significant changes which would substantiate supplement company claims. Supplement companies who push Glutamine, rely solely on in vitro and not in vivo results. The only documented benefits from using glutamine is when it is administered via IV in a peptide form and only to individuals who have suffered a severe trauma (ie: burn victims, cancer patients).

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
 
KIAN said:
Actually, the mouth is the first step in the digestive process. This is covered in Biology101. But aside from that ...

Glutamine, whether as a free-form L-glutamine or as a peptide, does not and has not been shown to produce any significant changes which would substantiate supplement company claims. Supplement companies who push Glutamine, rely solely on in vitro and not in vivo results. The only documented benefits from using glutamine is when it is administered via IV in a peptide form and only to individuals who have suffered a severe trauma (ie: burn victims, cancer patients).

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
Click to expand...


Trauma is a term that can be used for getting under the weather or working out say in a Extreme Bodybuilding Life Style.

Glutamine in the peptide form IS stable, it the same principal of aminos in food.
Because they are in Protien "chains" and hence "protected" they are processed through the stomach and then into the intestine, where they pass through the lumen , LIKE OTHER FOOD is........

it is the ISOLATED AMINOs that are not protected that are ravaged by the PH changes in the gut.
 
wakefib said:
http://en.wikipedia.org/wiki/Glutamine
Click to expand...

"It is also known that glutamine has various effects in reducing healing time after operations. Hospital waiting times after abdominal surgery are reduced by providing parenteral nutrition regimens containing amounts of glutamine to patients"

Parenteral = intravenous. Now if we could administer glutamine IV at our leisure, we would actually redefine what recovery is all about.
 
Glutamine Peptides are only beneficial if administered via IV to trauma patients

OMEGA said:
Trauma is a term that can be used for getting under the weather or working out say in a Extreme Bodybuilding Life Style.
Click to expand...

I think you misunderstand the difference between 'fatigue' and 'trauma' as the latter has very serious implications and has nothing to do with being 'under the weather' or 'working out' to extreme levels of endurance.

I can only repeat that Glutamine in a supplemented form has no benefits to the physiology of a healthy individual and claims by supplement manufacturers can not and have not been supported outside of in vitro tests.

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
 
Re: Glutamine Peptides are only beneficial if administered via IV to trauma patients

KIAN said:
I think you misunderstand the difference between 'fatigue' and 'trauma' as the latter has very serious implications and has nothing to do with being 'under the weather' or 'working out' to extreme levels of endurance.

I can only repeat that Glutamine in a supplemented form has no benefits to the physiology of a healthy individual and claims by supplement manufacturers can not and have not been supported outside of in vitro tests.

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
Click to expand...


IT is quite possible that you are not familiar with intense training.
Seriuos bodybuilders that do cardio, and lift ( especially double days) WILL benifit form Glutamine PEPTIDE supplemention.
Or athletes who wish to alleviate soreness.

You forget that GLUTAMINE is the PREFERED source of fuel for the IMMUNE SYSTEM ( look it up) which is part of what governs recovery ability.

GLUTAMINE is prefered over CARBORHYDRATE, over FAT, over Protien, over Alcohal and any othe source of fuel for the immune system

Having a readily available AND DENSE SOURCE of Glutamine as in G-covery is a sure way to retrieve the benifits of Glutamine Supplemenation.

Medical journals site Parenteral delivery ( which say Glutamine peptides work), but its is quite short sighted to believe that Oral Administration could not do that same........


Food gives nutritents via oral adim, but one can also deliver nutrients via Parenteral N to the gut, Which is better?

this premise holds the same for GLUTAMINE PEPTIDES as well.......

Like food ORAL admininstration of Glutamine Peptides will yield untilization.........hence benifits.
 
Re: Glutamine Peptides are only beneficial if administered via IV to trauma patients

Omega said:
IT is quite possible that you are not familiar with intense training.
Seriuos bodybuilders that do cardio, and lift ( especially double days) WILL benifit form Glutamine PEPTIDE supplemention.
Or athletes who wish to alleviate soreness.
Click to expand...
Regardless of what intensity level an individual performs physical activity, they will never be classed as a trauma case unless they drop the entire weight stack on their head. Therefore, any possible benefits from the supplementation of Glutamine will not be seen. If it is a question of soreness you wish to address, then just increase your Omega 3 intake so that your Omega 3 to 6 ratio is 1:1 and hydrate yourself. No supplements required.

You forget that GLUTAMINE is the PREFERED source of fuel for the IMMUNE SYSTEM ( look it up) which is part of what governs recovery ability.

GLUTAMINE is prefered over CARBORHYDRATE, over FAT, over Protien, over Alcohal and any othe source of fuel for the immune system
Click to expand...
While it is true that Glutamine does infact support the immune system, an individual would not be able to consume glutamine via supplementation at levels which would produce measureable changes to their physiology. Increasing their intake further would only produce nausea and diarrhea.

Medical journals site Parenteral delivery ( which say Glutamine peptides work), but its is quite short sighted to believe that Oral Administration could not do that same........
Click to expand...
These medical journals which site the benfits of glutamine peptides administered via IV and only to trauma patients are the same medical journals which site that supplementing with glutamine or glutamine peptides via supplements produces no measureably benefits to subjects. The only mention of supplemental benefits of glutamine come via supplement companies who are unable to substantiate these claims.

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
 
your still not getting it
wrote clearly what the reality is and your continueing to dismiss it in not valid

does Glutamine Mysteriuosly become valuable when you go through Hospital doors?
Trauma is Trauma, the body is challeneged when abody builder does Cardio Double days or trains twice a day, if this is not trauma what is?

also commented on the fact that food are hydrolized by the body, and taken up by the body. G-covery (glutamine peptides) funtion on the same principal.

you Comment on OMEGA 3 '?s while interesting are not comparible to glutamine or the discussion proceeding forth.

Your still think its glutamine which is an isolated amino acid, its NOT.
 
well, besides what they have not yet proven about glutamine. ever since i start taking it, muscle soreness has gone away alot faster than when i wasn't taking it. on top of that, i have IBS, and it doesn't hurt nearly as much as before.
 
Re: Please make it stop !!

Omega said:
your still not getting it
wrote clearly what the reality is and your continueing to dismiss it in not valid
Click to expand...
I understand that the sole purpose of bringing this issue to the attention of members here is to promote your product. I have no problem with that. But the published facts with regards to supplementing with glutamine, either in a free form or as a peptide, along with my ethics, do not permit me to agree with what you are saying.

does Glutamine Mysteriuosly become valuable when you go through Hospital doors?
Click to expand...
Glutamine is very valuable ... especially to a supplement company (any supplement company) which relies on sales at the expense of consumers or published facts.

Trauma is Trauma, the body is challeneged when abody builder does Cardio Double days or trains twice a day, if this is not trauma what is?
Click to expand...
Visit the TRAUMA centre at your local hospital and count the number of bodybuilders who are performing cardio. Now count the number of people who are suffering from third degree burns. This is what 'trauma' is. What you are continually referring to is 'fatigue' and fatigue can be reduced simply by hydrating the body correctly and re-establishing electrolytes. Have a thorough read of how and why 'glutamine peptides' are used in the treatment of trauma patients and you will understand this issue better.

you Comment on OMEGA 3 '?s while interesting are not comparible to glutamine or the discussion proceeding forth.
Click to expand...
As my comment mentioned, 'If it is just a question of soreness you wish to address' as you previously mentioned in your posting, then a balanced Omega 3:6 ratio and hydration will work fine. I only posted that because you mentioned 'soreness'.


You posted a question and a poll.
Assuming this was not a rhetorical posting, you now have my feedback.
Let's just leave it at that.

_____________________________

KIAN PHILLIPS -- BSc/SpSc - CPT

.
 
why leave it at that?, why dont you ready the feedback of real people, with you know real results..........

or let me guess its a conspiracy theory foisted by me and the company to brainwash people .

or could it be that the product works?
I am firm in my position becuase its poppy cock, to say something does not work till you have tried it, and further it insults the intergity of users who have tried it and say in plain fashion that glutamine peptides work.

I am only represented the truth, and dont diparage you for sharing opinion and whatever point of view you have..................but when you over step bounds to say its just company profit, or that people are stupid and niave then that is WRONG...


lets leave it at that:)
 
I've been using Glutamine Select with BCAAs by Beverly Int. I take 10g during my workouts and 5g after. I've been doing it for a month now and I see a difference in my pump and overall size. But, my results might be because I changed the intensity of my workout and have been pushing myself to the max, Glutamine or not.
 
Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exercise.

* Wilkinson SB,
* Kim PL,
* Armstrong D,
* Phillips SM.

Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St. West, Hamilton, ON L8S 4K1, Canada.

We examined the effect of a post-exercise oral carbohydrate (CHO, 1 g.kg(-1).h(-1)) and essential amino acid (EAA, 9.25 g) solution containing glutamine (0.3 g/kg BW; GLN trial) versus an isoenergetic CHO-EAA solution without glutamine (control, CON trial) on muscle glycogen resynthesis and whole-body protein turnover following 90 min of cycling at 65% VO2 peak. Over the course of 3 h of recovery, muscle biopsies were taken to measure glycogen resynthesis and mixed muscle protein synthesis (MPS), by incorporation of [ring-2H5] phenylalanine. Infusion of [1-13C] leucine was used to measure whole-body protein turnover. Exercise resulted in a significant decrease in muscle glycogen (p < 0.05) with similar declines in each trial. Glycogen resynthesis following 3 h of recovery indicated no difference in total accumulation or rate of repletion. Leucine oxidation increased 2.5 fold (p < 0.05) during exercise, returned to resting levels immediately post-exercise,and was again elevated at 3 h post-exercise (p < 0.05). Leucine flux, an index of whole-body protein breakdown rate, was reduced during exercise, but increased to resting levels immediately post-exercise, and was further increased at 3 h post-exercise (p < 0.05), but only during the CON trial. Exercise resulted in a marked suppression of whole-body protein synthesis (50% of rest; p < 0.05), which was restored post-exercise; however, the addition of glutamine did not affect whole-body protein synthesis post-exercise. The rate of MPS was not different between trials. The addition of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery.

PMID: 17111006 [PubMed - in process]
 
i have a nightime stack for hgh since im 17 and im hoping to bust an extra inch out..............its consists of 2-3g gaba, 2g alpha gpc, and 5g glutamine...............you think i should ditch the l-glutamine?
 
It seems that I will be changing my position on oral glutamine. Thanks to some studies at which I have just found , it appears that oral glutamine is not worthless at all and the first pubmed study showed that blood concentrations of glutamine actually rose post exersize

So I have to disagree with both Kain and MikeMartial

There are also studies to suggest that glutamine is not totally worthless

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=10368336&dopt=Abstract


http://www.ijp-online.com/article.a...7;issue=3;spage=148;epage=154;aulast=Kulkarni
MikeMartial said:
Well, there's enough studies out there now that have debunked L-glutamine. It's well know that supplement manufacturer's used intravenous studies of high-dose glutamine to fuel sales of oral L-glutamine.

The only thing that's keeping L-glutamine on store shelves is 1) Supplement companies pushing it, and 2) Anecdotal evidence.

'nuff said about that, since we've been through this before. But on to peptides.....

I was actually about to order some glutamine peptides from Trueproteincanada.com, to try for myself. Like I've said before, if peptides are actually able to do what l-glutaime can't, I'd be one happy camper, since I beat the shit outa my body weekly.

But it looks like the pH tolerance of glutamine peptides, while much better than L-glutamine, doesn't cut it in the stomach enviroment.
Click to expand...
 
Here's another one for your asses

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=10683095&dopt=Abstract
1: Int J Sports Med. 2000 Jan;21(1):25-30. Links
The effect of free glutamine and peptide ingestion on the rate of muscle glycogen resynthesis in man.

* van Hall G,
* Saris WH,
* van de Schoor PA,
* Wagenmakers AJ.

Department of Human Biology, Maastricht University, The Netherlands. [email protected]

The present study investigated previous claims that ingestion of glutamine and of protein-carbohydrate mixtures may increase the rate of glycogen resynthesis following intense exercise. Eight trained subjects were studied during 3 h of recovery while consuming one of four drinks in random order. Drinks were ingested in three 500 ml boluses, immediately after exercise and then after 1 and 2 h of recovery. Each bolus of the control drink contained 0.8 g x kg(-1) body weight of glucose. The other drinks contained the same amount of glucose and 0.3 g x kg(-1) body weight of 1) glutamine, 2) a wheat hydrolysate (26% glutamine) and 3) a whey hydrolysate (6.6% glutamine). Plasma glutamine, decreased by approximately 20% during recovery with ingestion of the control drink, no changes with ingestion of the protein hydrolysates drinks, and a 2-fold increase with ingestion of the free glutamine drinks. The rate of glycogen resynthesis was not significantly different in the four tests: 28 +/- 5, 26 +/- 6, 33 +/- 4, and 34 +/- 3 mmol glucosyl units x kg(-1) dry weight muscle x h(-1) for the control, glutamine, wheat- and whey hydrolysate ingestion, respectively. It is concluded that ingestion of a glutamine/carbohydrate mixture does not increase the rate of glycogen resynthesis in muscle. Glycogen resynthesis rates were higher, although not statistically significant, after ingestion of the drink containing the wheat (21 +/- 8%) and whey protein hydrolysate (20 +/- 6%) compared to ingestion of the control and free glutamine drinks, implying that further research is needed on the potential protein effect.

PMID: 10683095 [PubMed - indexed for MEDLINE]



gjohnson5 said:
It seems that I will be changing my position on oral glutamine. Thanks to some studies at which I have just found , it appears that oral glutamine is not worthless at all and the first pubmed study showed that blood concentrations of glutamine actually rose post exersize

So I have to disagree with both Kain and MikeMartial

There are also studies to suggest that glutamine is not totally worthless

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=10368336&dopt=Abstract


http://www.ijp-online.com/article.a...7;issue=3;spage=148;epage=154;aulast=Kulkarni
Click to expand...
 
Huh. I haven't popped onto this board in a while; I didn't expect this thread to be resurrected.

The rate of glycogen resynthesis was not significantly different in the four tests: 28 +/- 5, 26 +/- 6, 33 +/- 4, and 34 +/- 3 mmol glucosyl units x kg(-1) dry weight muscle x h(-1) for the control, glutamine, wheat- and whey hydrolysate ingestion, respectively. It is concluded that ingestion of a glutamine/carbohydrate mixture does not increase the rate of glycogen resynthesis in muscle.
Click to expand...

Glutamine IS an insulin secretagogue and an alkaline pH buffer, but I still question the efficacy vs cost benefit of either. For guys who have been loading heavy PWO, the glycogen repletion would explain the decreased DOMS; but honestly, solid PWO nutrition does the same, and acetic acid has been shown to be superior to glutamine in that department---for a fraction of the cost.

As far as pH buffering, NaHC03 works a helluva lot better, and once again costs a fraction. Not many people delve into this, though.

Is it totally worthless? To the average athlete, yes. To the elite athlete? IMO, still yes. To the critically ill? No. To supplement companies looking to make a huge profit? It's gold.
 
MikeMartial said:
Hehe, no offense taken. ;)

In all seriousness, Omega, I did offer to test G-covery a long time ago, and report my findings back here. Like I said then, I'm the perfect candidate: I resistance train, I do HIIT, I train in two completely different martial arts (Muay Thai and No-gi jujitsu), I have a very physical job as firefighter/paramedic, and I do shiftwork. If anyone needs better recovery, it'd be me.

Offer still stands: You send me some G-covery, and I'll log my findings on EF.
Click to expand...

OMEGA said:
PROOF IS IN THE PUDDING I SAY

try G-covery and tell me it does not work.............

asshats
Click to expand...

Offer still stands. L-glutamine and glutamine peptides are perfectly legal in Canada, so border issues aren't an excuse.
 
Do you seriously think the pro's use Glutamine? C'mon! It's the juice that gets ya big....better recovery? Maybe......maybe not.....the fact is that in reality....the average joe with average genetics can gain 5-10 pounds of LEAN body mass a YEAR! Dat's it! Regardless of what sups you use.....saturating with proteine....is a good eg......body wont care....so you may feel fuller....so what? 5-10 lbs....remember dat....unless you use juice...
 
i would say its neither. it helps but not much. your body doesnt get much from it. it doesnt break down well.
 
Pweeb said:
Do you seriously think the pro's use Glutamine? C'mon! It's the juice that gets ya big....better recovery? Maybe......maybe not.....the fact is that in reality....the average joe with average genetics can gain 5-10 pounds of LEAN body mass a YEAR! Dat's it! Regardless of what sups you use.....saturating with proteine....is a good eg......body wont care....so you may feel fuller....so what? 5-10 lbs....remember dat....unless you use juice...
Click to expand...


i think they use every available tool including glutamine. obvously they use all the illegal stuff but you would not make it to a pro status without trying it all and seeing what works then adding it to their schedule. how about coleman with his tackle box full of caps. do you think thats all oral aas and vitamins? its sups. some of them work.
 
I have also gathered the understanding that AKG ( Alpha Ketoglutarate or Alpha Ketoglutaric Acid) once combined with ammonia from your workout will create glutamine. So one way to build cellular glutamine stores is to workout hard and supplement with the deemed useless AKG's ( especially Orthnine AKG) But my understanding is that this is a slow process
 
Dont mean to rock your boat but going to rock lots of peoples boats here with the truth. I'm about truth and bringing it to this board.
Glutamine is a WASTE of money unless you have GI issues where it is utilized almost exclusively and rapidly turned to glucose to regrow lining of digestove tract which renews itself about every 3-6 days.
Keep on track here kuz now it gets good!!!
Glutamine does help the gut to HEAL! As for increased muscle please dont waste your money..

Because your small intestine uses most of it as energy even over glucose. Therefore, a large amount doesn't make it into your blood and if it did, you'd have problems..............

We experimented with a couple glutamine based dipeptides and they worked t make me VERY agitated which is exactly what happens when large amounts glutamine get into the bloodstream and then cross the blood brain barrier and convert to glutamic acid/glutamate. This is a poison to the brain.

glutamine, if it does get into the blood stream, can be converted to glutamate in the brain via glutaminase.

As I've stated before with the use of glutamine dipeptides which I had to quit using because they caused agitation due to this very problem if your glutamine was getting into your blood stream you'd notice it.

You'd notice it, but that's about the worst thing could do as glutamate is bad news:


If you aim to preserve keen mental function into your later years, supplementing. with methylcobalamin is a smart move at any age. Methylcobalamin guards brain function by eliminating homocysteine and by protecting against neurotoxicity induced by glutamate, aspartate and nitroprusside (Eur Journal Pharm). Glutamate is a neurotransmitter involved in communication between brain neurons, which causes brain cell death when present in excessive amounts.



The neurotransmitter dopamine maintains normal nervous system and motor control Qf muscle. When brain cells are damaged or destroyed, they can no longer produce adequate dopamine and the result is Parkinson's disease that affects 1 in 100 people over the age of 65. Methylcobalamin benefits those suffering from Parkinson's for two reasons. First, it is a cofactor to the production of dopamine and other brain neurotransmitters. Second, it protects against glutamate-induced neural toxicity caused by L-dopa and Sinemet drug therapies prescribed for Parkinson's patients. Research recommends 1 to 5 mg a day of sublingual methylcobalamin for prevention of Parkinson's, and 5 to 20 mg for treatment.


You might also want to read this on how potentially harmful glutamine has been found to be and frankly from my point view, recommending glutamine is about as smart as recommending heroin use though I guess most of you are lucky your glutamine is bunk since it's not reaching your brain as you aren't wasting your brain like you are wasting your money!

Is Glutamine Supplementation Helpful or Harmful? 5/1/04

We are looking to protect our brains here, so buy yourself a good protein as your gut is going to absorb most of the glutamine taken seperately!

any questions on supplements please contact me at [email protected] I will get back to you asap. I am bound by laws to only comment on that which is entirely legal where you might reside.

Thanks,

Mark
 
I have gi issues that get worse with supplements. So i use bcaa with glutamine. I notice that im able to use more protein without getting constipated. So far i feel more regular which helps when trying to cram down 4000+ calories.
 
This is an old thread, but is still relevant.
From the posts in this thread linking to studies its allready safe to conclude:
-Glutamine (as free aminoacid) is absorbed from the GI tract in significant amounts: (altough much is also broken down in the intestine,
this however can be reduced if glutamine is given along with f.ex alanine. It does not need to be in the dipeptide form)
so at least we can conclude that glutamine reaches systemic circulation after oral use.

My own view of glutamine is that its such a common aminoacid in protein, that you only would need to use it combined with BCAA during your workout,
or when its been a couple of hours since last meal.
the benefits i hope to get from glutamin is:
-more resistance to Cold/flu : stimulation of the immune system.
-to prevent catabolic states when combined with BCAA
People on this thread has allready stated correctly that glutamine is used as a fuel for the white blood cells (like macrophages),
it may also stimmulate cells in the immune system in various ways: proliferation, cytokine release, etc
and lastly: it will aid the digestive system/enterocytes,
which is also very important for immune function.
Glutamine seems to be needed for mTOR activation (along with BCAA), which makes sense,
as the body's glutamine stores will reflect total protein Balance. (Glu is a very common aminoacid in protein)

So as for elite athletes or chemically enhanced athletes, who's bodies are under constant stress,
I think glutamine (along with BCAA) will aid the immune system,
and help create an anabolic enviroment.

As for the talk about glutamine being poisonous because it converts to glutamate in the brain (which would cause the same excitotoxicity as large doses of MSD,
this is not seen in individuals given even large doses. Keep in mind that while glutamine can convert to glutamate, this is in turn converted to GABA by glutamate decarboxylase,
so glutamine wil provide precursors to both excitatory & inhibitory nerotransmitters in the brain.
 
ncbi.nlm.nih.gov/pmc/articles/PMC4272512/

This is the whole article, not just an abstract about glutamine, BCAA & Arginine.
It is from 2014 and reviews some of the current research.
 
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