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Fukkenshredded
New member
GHB does NOT cause withdrawals. I have posted repeatedly about this. Now there is a study backing it up:
The abrupt cessation of therapeutically administered sodium oxybate (GHB) does not cause withdrawal symptoms
J Toxicol Clin Toxicol 41(2), 131-5 (2003)
Medline (PMID=12733850)
Sodium oxybate (gamma-hydroxybutyrate; GHB) has demonstrated efficacy for the treatment of narcolepsy. However, there are reports of withdrawal following chronic abuse of illicit GHB which involve escalating both doses and dosing frequency. The present trial afforded an opportunity to test the hypothesis that chronic daily therapeutic dosing of sodium oxybate in narcoleptics does not cause withdrawal following abrupt cessation. Fifty-five narcoleptic patients, taking sodium oxybate (dose range 3-9 gm/night) for 7-44 months (mean 21 months), were randomized into a 2-week double-blind period: 29 patients received placebo and 26 continued to receive sodium oxybate. During this 2-week trial period, the following symptoms were reported in patients receiving placebo (N): anxiety (2), dizziness (1), insomnia (1) and somnolence (1). While these symptoms may represent possible symptoms of mild GHB withdrawal, they are also highly consistent with the returning symptoms of narcolepsy. We conclude there is minimal evidence of withdrawal symptoms following abrupt cessation of chronic sodium oxybate dosing in the therapeutic range.
See?
Also, when I did GHB I would stay on for MONTHS, 24/7. NEVER had anything even resembling a withdrawal.
The 'withdrawals' are a combination of metabolic acidosis (Caused by either GBL or improper pH in poorly made GHB) and dopamine surges. Both can be controlled fairly easily.
Anyway, I am tired of arguing this point, and as has been stated (in fact first by ME nearly a year ago...do a search for a thread called 'watch out' ) this subject is best avoided here.
The abrupt cessation of therapeutically administered sodium oxybate (GHB) does not cause withdrawal symptoms
J Toxicol Clin Toxicol 41(2), 131-5 (2003)
Medline (PMID=12733850)
Sodium oxybate (gamma-hydroxybutyrate; GHB) has demonstrated efficacy for the treatment of narcolepsy. However, there are reports of withdrawal following chronic abuse of illicit GHB which involve escalating both doses and dosing frequency. The present trial afforded an opportunity to test the hypothesis that chronic daily therapeutic dosing of sodium oxybate in narcoleptics does not cause withdrawal following abrupt cessation. Fifty-five narcoleptic patients, taking sodium oxybate (dose range 3-9 gm/night) for 7-44 months (mean 21 months), were randomized into a 2-week double-blind period: 29 patients received placebo and 26 continued to receive sodium oxybate. During this 2-week trial period, the following symptoms were reported in patients receiving placebo (N): anxiety (2), dizziness (1), insomnia (1) and somnolence (1). While these symptoms may represent possible symptoms of mild GHB withdrawal, they are also highly consistent with the returning symptoms of narcolepsy. We conclude there is minimal evidence of withdrawal symptoms following abrupt cessation of chronic sodium oxybate dosing in the therapeutic range.
See?
Also, when I did GHB I would stay on for MONTHS, 24/7. NEVER had anything even resembling a withdrawal.
The 'withdrawals' are a combination of metabolic acidosis (Caused by either GBL or improper pH in poorly made GHB) and dopamine surges. Both can be controlled fairly easily.
Anyway, I am tired of arguing this point, and as has been stated (in fact first by ME nearly a year ago...do a search for a thread called 'watch out' ) this subject is best avoided here.
