Hello,
Glutamine supplementation has been touted as one of the missing pieces of the hypertrophic/anti-catabolic puzzle for intensely training athletes. Many have felt it to be beneficial in training, particularly when dieting, training very frequently and very intensely.
Up until now, some of the drawbacks to oral glutamine supplementation was the absorbability factors. The L-form just required mass amounts to pass the gut membrane and be taken up to target tissues. As a result, much was wasted. But now, with the advent of peptide bonded forms of glutamine, this problem has been efficiently overridden. The peptide glutamic substrates are taken up much more easily, and as a result, much higher plasma concentrations are achieved, with much less required to achieve this end result.
Now, with this in mind, one may still question, "Why glutamine? What will it do for me, the athlete?"
Glutamine is the most abundant occuring amino acid present in the entire body, comprising about 75% of the muscle cell amino acid pool.
During stress, the body's requirement for glutamine often appears to excedeour ability to produce sufficient amounts to reinstate cell pool homeostasis. Stress causes increased amounts of glutamine to release from muscle, and it becomes difficult to restore, presumably as a result of disturbances of the Na+electrochemical gradient across the cell membrane. Liver and spleen uptake of glutamine is also increased during these stressful times, further displacing the content present in muscle.
Low plasma concentrations of glutamine reflect reduced stores in muscle tissue. Feeding extra amounts of readily available/easily absorbed peptide bonded glutamine during these periods would be a wise idea to counterattack these catabolic mechanisms and sustain the muscle amino pool content.
On a cellular level, let's take a look at why glutamine is such a worthwhile substrate----Some of its proven benefits:
*It attenuates glutathione depletion( Glutathione is the most important endogenous scavenger system/anti-oxidant in the entire body). Glutathione depletion is often pronounced after bouts of stress, including events of high intensity excercise such as we subject ourselves to during heavy training.
*Glutamine has been shown to stimulate/activate protein synthesis and inhibit turnover(degradation). It has been shown to enhance/sustain nitrogen homeostasis under periods of stress.
*Glutamine modulates lymphocyte (immune cell) activation,by proliferating (increasing population)of T-Cell numbers which in turn increases immune system response. Parenteral administration in hospital patients under stress has been found to greatly decrease the instance of bacterial infections. For the rest of us we can achieve those same benifits via supplemenation of Glutamine Peptides
*Stimulates hepatic(liver)glycogen synthesis.
*Glutamine has also been shown to enhance stress-induced heat shock protein(HSP)expression. HSP's provide protection of cellular injury.
*Lastly, glutamine peptides have the antioxidant action similar to 3-5 servings of fruit or vegetables based on ORAC (oxygen radical absorbance capacity) for vitamins C, E, and beta-carotene. Glutamine peptides offer 300 times more ORAC antioxidant equivalents as compared to free glutamine.
SOURCE ORAC INTAKES
Vitamin E (500mg) 116
Vitamin C (500mg) 2830
3-5 servings of fruits and vegetables 1950
B-carotene (250mg) 300
Bound amino acid glutamine (5-7g) 3.5-5.4
Protein hydrolysate (10-15g) 1100-1650
oral administration of glutamine,particularly in peptide-chained form very well may improve nitrogen economy/retention, improve repair/recovery of damaged muscle tissue,and diminish the the incidence of free radicals/bacterial forms present in those who are placing stress on their systems through the routines of high intensity training.
PROFILE
glutamine 373 mg ++++conditionally essential
alanine 26 mg
arganine 29 mg
aspartic acid 30 mg
cystiene 15 mg
glycine 35 mg
histidine 20mg
isoluecine 40 mg ++ essential amino
luecine 70 mg ++ essential amino
lysine 14 mg ++ essential amino
methionine 15 mg ++ essential amino
phenylaline 53 mg ++ essential amino
proline 132 mg
serine 44 mg
threonine 22 mg ++ essential amino
tryptophan 8 mg ++ essential amino
tyrosine 34 mg
valine 40 mg ++ essential amino
elemental profile
sodium
potasium
calcium
magnesium
phosphorus
chloride
iron
Natural Flavors
STACKING EnerG with CEE would be assured lean mass gains
5 grams CEE on workout days
2.5 grams CEE on off days
50 grams EnerG on workout days
25 grams EnerG on off days
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