yes, the nicotine in copenhagen or skoal is definitely bad for protein synthesis, but it also acts to suppress appetite, which hurts too!!! a real world example of this are the skinny bitches that balloon up in weight when they stop smoking, its the nicotine and tar that no longer suppress their appetites, and like every typical American, they are just afew chesseburgers away from obesity. AMerica is an obese society - the rich, the poor, everyone, we're f-ing FAT!! its sick...