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cancer and anabolics...

SheHuLK

New member
i know this is the HIV board, but i figured the people here might be able to help me out with my question, being that HIV and cancer although very different, have many similarities. i know that anabolics are given to HIV patients as well as ones with cancer. which brings me to my question...

i used to have leukemia, CML (chronic myelogenous leukemia) a type of cancer of the bone marrow resulting in an abnormal (high) amount of white cells. i had a bone marrow transplant over 3 years ago, this put my disease into remission..technically not considered 'cured' until in remission for 5 yrs.

Although my transplant was a success, i never acquired something known as GVH (graft vs. host disease). this is when the graft-the donor bone marrow, attacks the host's body-in this case mine. too much GVH is deadly, however mild GVH is good... this is sort of an insurance policy, getting mild GVH is a sign that the new donor bone marrow is active in your system, fighting off all leukemic cells left over. this is also known as the GVL (graft vs. leukemia) effect. I never had any GVH, some people never do.

everything was fine, then 2 yrs post transplant some residual leukemic cells were detected in a routine bone marrow biopsy. the fact that i never had any GVH made my doctors believe that i had not relapsed, these were residual cells 'left over' after transplant.

to fix this, i received donor stem cell infusions, attempting to stir things up a bit, and cause some GVH... the infusions began at low dosages of cells, since everyone reacts different. the residual cells have not since reappeared, but yet i still haven't gotten any GVH from the stem cell infusions. i was also put on Gleevec (a new med which is used to treat patients with CML) as a percaution, to help eliminate residual leukemic cells, and maintain a long and healthy remission.

what does this mean? pretty much means that i am fine, but there is no way of guaranteeing that there aren't any more residual cells lurking around, since they cant test ALL the cells in my body at once.

i am at a point now in my training where i am considering doing my first cycle, probably some anavar at 5mg a day, and i was wondering if that would interact at all with my meds/stem cell treatment.. and how it would effect my blood cell counts in general?

ofcourse before doing anything, i will consult my doctors..BUT i don't know how close minded they might or might not be about something like this.. so I want to get as much info on this as i can on my own before approaching them. thanks :)

shehulk
 
Now that was a post....

Shehulk send me a private message so that I can put you in contact with a hormone specialist. He can break down the side effects as well as the benifits. I don't normaly give his number out but in this situtation a normal MD will just screw things up for you, he knows more about hormone therapy than 99% of the Dr's out their. He may also be able to help get anabolics for you legally with a perscription, and just maybe you can get medical coverage.
 
hey 21inch_arms :) Thanks for replying. It would be great if you could really put me in contact with that hormone specialist, it would help me out tremendously. I sent you a PM... PM me back or email me whenever you can ;)

*SheHuLK*
 
SheHulk--I hope things work out for you! Please let me know what the endocrinologist says. I am under the impression that anabolic side-effects suppress the immune system to a certain extent. I am interested as to what effect anavar might have on your immune system-as far as haemotopoesis and B and T cell differentiation and also suppressing the GVH response. Good luck.
 
This is ancient thread I dug up because I'm in a similar situation. Last Feb. I was diagnosed with Acute Myeloid Leukemia. Leading up to this I was in great shape and had run a test cyp and eq cycle three years earlier. 10 months of chemotherapy will wreak havoc on your body. The good news is I'm finally finished up everything and have started getting back into the gym.

Right now is my first week and I'm just doing basic cardio and light machine work. In the next few weeks I'll work back into free weights and my old split and plan to eat and train hard for probably a year check my gains. Thank god for muscle memory.

My real question is does anyone have any references on using anabolic steriods post leukemia treatment. Being that leukemia is a bone marrow thus blood disorder I wonder if after being in remission if steriods would cause the cancer to start again. If anyone has any knowledge of this I'd love to hear it. Thanks.
 
spastic_gramps said:
I wonder if after being in remission if steriods would cause the cancer to start again. If anyone has any knowledge of this I'd love to hear it. Thanks.


Im a lymphoma survivor, I have wondered about this question myself, although I have never used roids or ever will. Steroids have been linked to cancer although the research isnt that strong.

I wouldnt do it, I stick to as much organic foods as I can.
 
OK. I'm in for this one. One of my HIV doctors is the world famous Dr. Bruce Dezube of BI in Boston. He claims that for PWA's that use HGH, that when cancer shows up in them, that HGH is found in the tumors. So, for right now, he is against using HGH for PWA's. Now, the problem with his logic - and he IS one of the best HIV docs in the country - that for anyone using HGH, you could probally find it in all sorts of tissue in the body. So, I don't think it makes any sence. If I could, I would put myself on HGH right now (but in small amounts.) Thanks! Alan Chiras.
 
I have had two large chunks of my head removed due to Melanoma. Also lost a lymph gland. Thank you plastic surgery. Anyway....as a former decade long user of gear and national competitor 25 years ago...trainer of nationally ranked men and one female using gear....a question. Are you planning on competion?? If not then....why risk it? Female side effects are unwanted hair, flat boobs, deepening voice, acne, raised RBC, pissed off attitude and enlarged clit (good thing/bad thing). School is out on anabolics and cancer connection. Flip a coin. HRT is a 100% NO NO.

If you are going to compete and are a chance taker then Anavar and Clen arte the cleanest for females. Major blood test every 6 weeks. If you are looking to sword fight with your significant other then a nightly rub a dub dub on the little man in the boat with AndroGel will do the trick.
 
21inch_arms said:
Now that was a post....

Shehulk send me a private message so that I can put you in contact with a hormone specialist. He can break down the side effects as well as the benifits. I don't normaly give his number out but in this situtation a normal MD will just screw things up for you, he knows more about hormone therapy than 99% of the Dr's out their. He may also be able to help get anabolics for you legally with a perscription, and just maybe you can get medical coverage.
your out of the red now ,keep on helping people :)
 
I'm currently in medical school right now and am in the midst of my hemonc unit. I'm sure you're well aware that anabolic steroids can cause polycythemia (elevated RBCs) due it's stimulatory effects on the bone marrow. This effect alone would be enough for me to be convinced that you should NOT attempt it. CML by itself is not the end of the world because Gleevec was a revolutionary drug that really works wonders with the disorder (it specifically targets the philadelphia chromosome fusion gene BCR/ABL in CML). However, you may still have that one or two CML myoblasts hovering around in your system and if the anabolics trigger relapse you're back to square one. And who knows, if you progress to ACUTE myelogenous leukemia - you're pretty much dead. Talk to your physcian though because anabolic steroids are prescribed in many chronic wasting diseases (cancer, AIDS, etc.) legally.

I also wouldn't bother talking to an endocrinologist - talk to an hematologist/oncologist instead.


edit - Oh, I guess I'm replying to the guy with AML now. Hmm...honestly AML is a lot worse than CML so I would assume it warrants more caution. I won't go into the details because I'm sure you are well aware of how much the disease sucks and you don't need some punk med student telling the world how hard you got it. Either way, talk to your physcian and ask him his opinion. Tell him you learned that anabolic steroids have been used in patients in cancer and you are wondering if it could be an option for you.

Best of luck, man. Hope everything works out well.
 
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