I use 1cc or 1000mcg when ever I start feeling sluggish or sick. I generally use it 2-3 times a month. If you want to use it to stimulate your appetite you will probably need to use it 2 or more times a week. When I use it eod I notice an increase in appetite and much more energy. It boosts your immune system and makes me feel more energetic and healthy. If you take the tabs you will need to use a much higher dose but they will work just as well in the long run.