Actually in low doses var improves lipid panels... I know, I had my dad( an MD) put a friend of ours with liver cancer on anavar at 15mg/day. Not only has he lived 3 months longer than he was given, he's still working 8hrs a day, his 3 liver tumors has not grown at all, and his lipids and liver enzymes have improved slightly. In general though, ALL 17aa will kill your lipids, either take things like policosanol, niacin, diet, EFA's, etc., to try and keep them in check, or just remember than a 4-week change in HDL levels has been proven so far to have NO effect on heart disease.