the difference is like night and day. look at the absolute best muscle building foods here is a meal fresh steak cooked only enough to make it safe to eat, sweat taters as close to raw as possible and broccoli as close to raw as possible and a glass of milk. if you where to eat meals like this with some variation 6-10 times per day with proper training and recovery you will grow. now look at the best powdered shakes, bars, cookies, puddings ect in existance. they are all highly processed and always have one thing in common the protein comes from powder. the process that takes milk, meats, eggs and turns them into a powder that has a verry long shelf life is what makes it your worst possible source of protein.
if you question this try an experiment.
eat the real food like my example for 1 month and chart your stats. then eat nothing but shakes and bars for 1 wk and see how much muscle you lose.
sup. meals should definately be reserved for when you have no other choice.