Excuse the bump, but this thread is one worth bumping, as it's a long-term issue...
Here's what I find so far, and I've been on 1/2mg EOD or E3D,  for several months: 
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The Good:
Libido ^ maybe 20%
NO PROBLEM in the hard dept, and that had been a problem for me at times.
Endurance and stamina; WAY WAY up! 
Gives me a really good-looking tan, even if I haven't been in the sun much.
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The bad:
Side effect of nausea; very slight, but I don't do well with any nausea.  It's never actually made me sick all the way, but it goes to that feeling of "unsure". 
Bee-sting-like reaction at needle site.  It feels just like a bee sting for about 5 minutes, then goes away.  No swelling or anything else; just the sting.
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The unsure:
Lower semen volume.  Not sure if or if so how, the PT141 is related to that.  I still feel like there's a big load, but there's not much actually there. 
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Charles