Yes.
If you are a novice you can start with 5x5 StongLifts, Starting Strength... They are good programs for beginners. It will give you muscle and strength. The progression is very linear and easy to follow and understand. When you can't go any further with these programs you will need a different approach. Remember to gain muscle you should eat for that.
If you are a intermediate lifter is better to divide your training into phases. Hypertrophy, Strength and Peaking. Considering your goal is Powerlifting... so you want to Squat, Bench and Deadlift as many weight as you can.
Hypertrophy: you add volume to your training... in competitive movements and accessories... to add some muscle and correct weakness.
Strength: you cut volume and increase intensity. In this phase I cut volume in competitive and accessories lifts and I work with different intensities during the mesocycle.
Peaking: is where you gonna be most specific you can be. In this phase You only Squat, Bench and Deadlift, You work only with singles, doubles and triples. Accessories is very limited and the most specific it can be. This phase you are going to train with all year you use in competition.
Remember... hypertrophy phase must be the longest of your macrocycle ... taking at least 50% of the entire cycle ... followed by the strength phase with 30-35% and peaking, which should be the shortest phase, not to exceed 15-20% of the whole macrocycle.
Keep a log of your training, this will help you understand and manipulate your program... You will be able to analyze what works and what doesn't.
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