Trenannosaurus
New member
Severe PIP and inflammation from pretty much every compound. Anyone experienced this?
I've been having some pretty bad reactions to injections for a while now and I'm trying to figure out what's actually causing it because it's getting ridiculous at this point.
I've tried quite a few different compounds, including:
- Test P – 100mg/ml
- Test E – 250mg/ml
- Test C – 250mg/ml
- Primo E – 100mg/ml
- Mast P – 100mg/ml
Out of all of them, Primo E and Test P are by far the worst. Test E and Mast P are a lot more tolerable, but I still get reactions from them. Test C has also caused issues.
The problem isn't just your usual PIP. Pretty much every injection causes a hard lump or knot around the injection site, along with swelling, redness and heat. The area gets really hot to the touch and can be painful enough that it restricts my movement.
On top of that, I get flu-like symptoms, including fever, muscle and joint aches, fatigue, weakness and feeling like I need to sleep all day.
The inflammation and symptoms can last anywhere from 7–10 days after an injection.
I've attached a photo of what happened after injecting my shoulder. You can see how swollen and red the area gets, and there's a pretty noticeable lump underneath. Also, moves down to the tricep/bicep area which is frustrating this is following a primo 1ml injection. I've had to avoid primo due to this.
This happens almost every time I inject.
For some background, I've been injecting for a while and I'm confident my technique isn't the issue. I use a 25G 1-inch needle and rotate between my VG, lats and delts.
I've tried pretty much everything I can think of to reduce the PIP:
- Different carrier oils, including MCT, GSO and castor oil.
- Different suppliers and brands.
- Changing injection volumes, frequency and injection speed.
- Warming the vials up before injecting.
- Massaging the injection site after injecting.
- Even tried airing out some of the BA by inserting a needle into the vial and placing it in a bowl of hot water, but that made absolutely no difference.
The concentrations of BA and BB in the products I've used are unknown, which makes it harder to work out whether one of them is responsible.
Naproxen seems to help quite a bit with the pain and inflammation, but obviously that's just masking the symptoms rather than fixing whatever is causing them.
I've also been looking into homebrewing so I can have more control over the carrier oils and solvent concentrations, mainly to see if I can narrow down what's triggering these reactions.
What I find strange is that certain compounds are significantly worse than others, despite using different suppliers and carrier oils. If it were purely an issue with BA or BB, wouldn't I expect relatively similar reactions across all of them?
I'm starting to wonder whether I'm reacting to the actual compounds or esters themselves, rather than just the solvents.
Has anyone here dealt with anything similar? Particularly the hard, hot lumps that last for days alongside the flu-like symptoms?
Could it be a sensitivity to BA/BB, something to do with the hormone or ester, or some other inflammatory response?
Interested to hear what you guys think, especially if you've managed to figure out what was causing it and how you dealt with it.
I've been having some pretty bad reactions to injections for a while now and I'm trying to figure out what's actually causing it because it's getting ridiculous at this point.
I've tried quite a few different compounds, including:
- Test P – 100mg/ml
- Test E – 250mg/ml
- Test C – 250mg/ml
- Primo E – 100mg/ml
- Mast P – 100mg/ml
Out of all of them, Primo E and Test P are by far the worst. Test E and Mast P are a lot more tolerable, but I still get reactions from them. Test C has also caused issues.
The problem isn't just your usual PIP. Pretty much every injection causes a hard lump or knot around the injection site, along with swelling, redness and heat. The area gets really hot to the touch and can be painful enough that it restricts my movement.
On top of that, I get flu-like symptoms, including fever, muscle and joint aches, fatigue, weakness and feeling like I need to sleep all day.
The inflammation and symptoms can last anywhere from 7–10 days after an injection.
I've attached a photo of what happened after injecting my shoulder. You can see how swollen and red the area gets, and there's a pretty noticeable lump underneath. Also, moves down to the tricep/bicep area which is frustrating this is following a primo 1ml injection. I've had to avoid primo due to this.
For some background, I've been injecting for a while and I'm confident my technique isn't the issue. I use a 25G 1-inch needle and rotate between my VG, lats and delts.
I've tried pretty much everything I can think of to reduce the PIP:
- Different carrier oils, including MCT, GSO and castor oil.
- Different suppliers and brands.
- Changing injection volumes, frequency and injection speed.
- Warming the vials up before injecting.
- Massaging the injection site after injecting.
- Even tried airing out some of the BA by inserting a needle into the vial and placing it in a bowl of hot water, but that made absolutely no difference.
The concentrations of BA and BB in the products I've used are unknown, which makes it harder to work out whether one of them is responsible.
Naproxen seems to help quite a bit with the pain and inflammation, but obviously that's just masking the symptoms rather than fixing whatever is causing them.
I've also been looking into homebrewing so I can have more control over the carrier oils and solvent concentrations, mainly to see if I can narrow down what's triggering these reactions.
What I find strange is that certain compounds are significantly worse than others, despite using different suppliers and carrier oils. If it were purely an issue with BA or BB, wouldn't I expect relatively similar reactions across all of them?
I'm starting to wonder whether I'm reacting to the actual compounds or esters themselves, rather than just the solvents.
Has anyone here dealt with anything similar? Particularly the hard, hot lumps that last for days alongside the flu-like symptoms?
Could it be a sensitivity to BA/BB, something to do with the hormone or ester, or some other inflammatory response?
Interested to hear what you guys think, especially if you've managed to figure out what was causing it and how you dealt with it.

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