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Oxytocin .... Intense orgasms!!!

caligirl85 said:
I'm quite fascinated in this and am considering trying it. I also work in a child psychiatric hospital and we have had some discussions lately about the studies with oxytocin and specifically, Autism. A lot of the latest research was attempting to increase the children's ability for empathy and bonding and they haven't been overly successful but it's an area of potential and a lot more research. I'll post an update if I decide to try this!! :)
Click to expand...

Please do. It would be good to hear more peoples findings with his. Hopefully it is found to be useful for autistic kids after more research.
 
Elvia1023 said:
Please do. It would be good to hear more peoples findings with his. Hopefully it is found to be useful for autistic kids after more research.
Click to expand...

I've worked with autistic kids a lot. 20 years ago when I worked with them nobody knew what to do with them. Education has come a long way in understanding autism. I have yet to work with an autistic child who has been prescribed oxytocin but I find the premise fascinating.
 
wootoom said:
Well I jerk off 5 time a a day and service the old lady once...I might not need it LOLOLOL
Click to expand...

Y not service the old.lady 5 times then might not jerk it at all
 
Post from a Superior oxytocin user at another forum...

"Currently using 10mcg morning and 10mcg at night. My anxiety is gone in the day and I sleep like a baby at night. I would not suggest using it during the day if you aren't on caffeine of some sort."
 
Stress Reduction....

Oxytocin in the cardiovascular responses to stress.

AuthorsWsol A, et al. Show all Journal
J Physiol Pharmacol. 2008 Dec;59 Suppl 8:123-7.

Affiliation
Abstract
The present study was designed to determine the role of central oxytocin (OXY) in regulation of the cardiovascular responses to the alarming stress. Three groups of male, normotensive Sprague Dawley rats, received intracerebroventricular (i.c.v.) infusion of one of the following: 1) vehicle, 2) OXY or 3) OXY antagonist (OXANT). Mean arterial blood pressure (MABP) and heart rate (HR) were recorded at rest, during and after application of the alarming stressor (air jet). Under resting conditions the i.c.v. infusions of vehicle, OXY or OXYANT did not influence the cardiovascular parameters. The alarming stressor evoked significant increases in MABP and HR that were significantly greater in the rats receiving i.c.v. infusion of oxytocin antagonist than in those receiving vehicle or OXY. The study provides evidence that stimulation of the brain oxytocin receptors by endogenous oxytocin plays significant role in inhibition of cardiovascular responses to stress.
 
We left the 30% off discount code active today because someone always complains they were in a different time zone and the code didn't work when it should have. Take advantage of this and try out our oxytocin. Click on my banner for the website.
 
johnjuanb1 said:
We left the 30% off discount code active today because someone always complains they were in a different time zone and the code didn't work when it should have. Take advantage of this and try out our oxytocin. Click on my banner for the website.
Click to expand...

I couldn't find it on there. Is it under a different name?
 
Nest making and oxytocin comparably promote wound healing in isolation reared rats.

AuthorsVitalo A, et al. Show all Journal
PLoS One. 2009;4(5):e5523. doi: 10.1371/journal.pone.0005523. Epub 2009 May 13.

Affiliation
Abstract
BACKGROUND: Environmental enrichment (EE) fosters attachment behavior through its effect on brain oxytocin levels in the hippocampus and other brain regions, which in turn modulate the hypothalamic-pituitary axis (HPA). Social isolation and other stressors negatively impact physical healing through their effect on the HPA. Therefore, we reasoned that: 1) provision of a rat EE (nest building with Nestlets) would improve wound healing in rats undergoing stress due to isolation rearing and 2) that oxytocin would have a similar beneficial effect on wound healing.

METHODOLOGY/PRINCIPAL FINDINGS: In the first two experiments, we provided isolation reared rats with either EE or oxytocin and compared their wound healing to group reared rats and isolation reared rats that did not receive Nestlets or oxytocin. In the third experiment, we examined the effect of Nestlets on open field locomotion and immediate early gene (IEG) expression. We found that isolation reared rats treated with Nestlets a) healed significantly better than without Nestlets, 2) healed at a similar rate to rats treated with oxytocin, 3) had decreased hyperactivity in the open field test, and 4) had normalized IEG expression in brain hippocampus.

CONCLUSIONS/SIGNIFICANCE: This study shows that when an EE strategy or oxytocin is given to isolation reared rats, the peripheral stress response, as measured by burn injury healing, is decreased. The findings indicate an association between the effect of nest making on wound healing and administration of the pro-bonding hormone oxytocin. Further elucidation of this animal model should lead to improved understanding of how EE strategies can ameliorate poor wound healing and other symptoms that result from isolation stress.

PMID 19436750 [PubMed - indexed for MEDLINE]
 
Oxytocin promotes social bonding in dogs.

AuthorsRomero T, et al. Show all Journal
Proc Natl Acad Sci U S A. 2014 Jun 9. pii: 201322868. [Epub ahead of print]

Affiliation
Abstract
Recent evidence suggests that enduring social bonds have fitness benefits. However, very little is known about the neural circuitry and neurochemistry underlying the formation and maintenance of stable social bonds outside reproductive contexts. Oxytocin (OT), a neuropeptide synthetized by the hypothalamus in mammals, regulates many complex forms of social behavior and cognition in both human and nonhuman animals. Animal research, however, has concentrated on monogamous mammals, and it remains unknown whether OT also modulates social bonds in nonreproductive contexts. In this study we provide behavioral evidence that exogenous OT promotes positive social behaviors in the domestic dog toward not only conspecifics but also human partners. Specifically, when sprayed with OT, dogs showed higher social orientation and affiliation toward their owners and higher affiliation and approach behaviors toward dog partners than when sprayed with placebo. Additionally, the exchange of socio-positive behaviors with dog partners triggered the release of endogenous OT, highlighting the involvement of OT in the development of social relationships in the domestic dog. These data provide new insight into the mechanisms that facilitate the maintenance of close social bonds beyond immediate reproductive interest or genetic ties and complement a growing body of evidence that identifies OT as one of the neurochemical foundations of sociality in mammalian species.
 
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johnjuanb1 said:
Stress Reduction....

Oxytocin in the cardiovascular responses to stress.

AuthorsWsol A, et al. Show all Journal
J Physiol Pharmacol. 2008 Dec;59 Suppl 8:123-7.

Affiliation
Abstract
The present study was designed to determine the role of central oxytocin (OXY) in regulation of the cardiovascular responses to the alarming stress. Three groups of male, normotensive Sprague Dawley rats, received intracerebroventricular (i.c.v.) infusion of one of the following: 1) vehicle, 2) OXY or 3) OXY antagonist (OXANT). Mean arterial blood pressure (MABP) and heart rate (HR) were recorded at rest, during and after application of the alarming stressor (air jet). Under resting conditions the i.c.v. infusions of vehicle, OXY or OXYANT did not influence the cardiovascular parameters. The alarming stressor evoked significant increases in MABP and HR that were significantly greater in the rats receiving i.c.v. infusion of oxytocin antagonist than in those receiving vehicle or OXY. The study provides evidence that stimulation of the brain oxytocin receptors by endogenous oxytocin plays significant role in inhibition of cardiovascular responses to stress.
Click to expand...


Good shit!


Sent from my iPhone using Tapatalk
 
PHGHI said:
My 10 year old son is diagnosed with Autism. His doctor has me giving him 3ius of Oxytocin orally every morning to control his aggressive behavior in school. Been on this for four months and he's doing a lot better with interacting with bother kids. Very little aggressive behaviors in school. Just thought I share this.
Click to expand...


Glad to hear it, very interesting and great that you shared this
 
Post in my oxytocin thread at pm...

"So far I like it as a nighttime , dose it before bed. As far as during the next day I do feel more like talking to people and BSing about nothing. Which is not like me. I don't feel sluggish at all in the morning. It could be because I'm dosing pretty low."
 
GREAT STUDY ON OXYTOCIN AND ITS IMPORTANCE TO SKELETAL MUSCLE

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration.

AuthorsElabd C, et al. Show all Journal
Nat Commun. 2014 Jun 10;5:4082. doi: 10.1038/ncomms5082.

Abstract

The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation; however, systemic age-specific factors responsible for this phenomenon are largely unknown. Here we report that oxytocin-a hormone best known for its role in lactation, parturition and social behaviours-is required for proper muscle tissue regeneration and homeostasis, and that plasma levels of oxytocin decline with age. Inhibition of oxytocin signalling in young animals reduces muscle regeneration, whereas systemic administration of oxytocin rapidly improves muscle regeneration by enhancing aged muscle stem cell activation/proliferation through activation of the MAPK/ERK signalling pathway. We further show that the genetic lack of oxytocin does not cause a developmental defect in muscle but instead leads to premature sarcopenia. Considering that oxytocin is an FDA-approved drug, this work reveals a potential novel and safe way to combat or prevent skeletal muscle ageing.
 
The precious study really impresses me. To think oxytocin not only increases social ability and causes relaxation but it also rejuvenated skeletal muscle vitality. Impressive stuff!
 
I have some sildenafil 100mg. {Viagra] mixed with oxytocin 125iu.
So it must have something to do with sex or erection for a pharmacy to mix the two.
I received this by mistake from a compounding pharmacy last year. order was replaced with just sildenafil and I kept the first order for free. I will try it at a quarter percent.
I received them in troches so don't know if the effects will be the same as injection. will keep you posted.
 
markmark said:
I have some sildenafil 100mg. {Viagra] mixed with oxytocin 125iu.
So it must have something to do with sex or erection for a pharmacy to mix the two.
I received this by mistake from a compounding pharmacy last year. order was replaced with just sildenafil and I kept the first order for free. I will try it at a quarter percent.
I received them in troches so don't know if the effects will be the same as injection. will keep you posted.
Click to expand...

I'm in for this. Sounds like an interesting mix. Let us know how it goes. :)
 
Making old muscles new again with Oxytocin By Patrick Arnold

Oxytocin is a relatively small peptide hormone (nine amino acids) that is produced in the posterior pituitary gland. Although it is produced in both men and women, the most well known function of oxytocin is in females where it acts as a facilitator of uterine contractions during labor, and as a stimulator of milk release from the breasts in the post-partum period. More recent research has implicated oxytocin in the emotional bonding response that occurs between females and their infant offspring, and also that which occurs with adult romantic partners over time. You may have heard that oxytocin is released after sex especially in women (which may be why women tend to be more affectionate afterwards). Oxytocin is also FDA approved as a drug to facilitate labor in women and to help with post childbirth bleeding.

Like many hormones in the body, science is discovering that oxytocin may have a wide variety of actions on multiple tissues – activities beyond the classical ones for which it is most well known. Most recently evidence has popped up suggesting that oxytocin is a factor in the regeneration of muscle tissue and that its levels are suppressed with age.

Researchers at UC Berkeley published a paper demonstrating that oxytocin is an indispensable factor in the healthy repair and maintenance of skeletal muscle tissue. They used young and old mice and showed that levels of oxytocin in the older mice were much lower than the younger mice. Administration of oxytocin (by subcutaneous injection) for a few days restored the ability of muscle to repair itself in these older mice to levels seen in younger mice. Conversely, mice bred with inability to produce oxytocin were born normal but quickly developed sarcopenia (muscle loss associated with aging).

The mechanism of this enhanced muscle regenerative capacity is thought to be due to increasing the proliferation and activation of muscle satellite cells. Muscle satellite cells are known to decrease with aging and they serve a key role in muscle recovery and growth. Injury (exercise induced or via trauma) causes the release of certain chemical signals which stimulate satellite cells to fuse with their parent muscle cells where they add myonuclei (the powerhouse of protein synthesis within the muscle cell).

It has been shown previously that muscle cells possess functional oxytocin receptors and that muscles themselves can manufacture oxytocin. One study in particular showed that in cattle the expression of oxytocin in muscle is increased dramatically in cattle receiving the anabolic steroid implant Revalor H, and it is speculated that oxytocin may be related to the increased muscle mass that results. The UC Berkeley study now shows that direct systemic administration of oxytocin may have positive effects upon skeletal muscle as well.
 
Oxytocin increases trust in humans.

Authors
Kosfeld M1, Heinrichs M, Zak PJ, Fischbacher U, Fehr E.
Author information
Journal
Nature. 2005 Jun 2;435(7042):673-6.

Affiliation
Comment in
Nature. 2005 Jun 2;435(7042):571-2.
Rev Med Suisse. 2005 Jun 8;1(23):1592.
Abstract
Trust pervades human societies. Trust is indispensable in friendship, love, families and organizations, and plays a key role in economic exchange and politics. In the absence of trust among trading partners, market transactions break down. In the absence of trust in a country's institutions and leaders, political legitimacy breaks down. Much recent evidence indicates that trust contributes to economic, political and social success. Little is known, however, about the biological basis of trust among humans. Here we show that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions. We also show that the effect of oxytocin on trust is not due to a general increase in the readiness to bear risks. On the contrary, oxytocin specifically affects an individual's willingness to accept social risks arising through interpersonal interactions. These results concur with animal research suggesting an essential role for oxytocin as a biological basis of prosocial approach behaviour.
 
cooool.......

Just couple simple questions.

Does anyone know if shooting this shit will cause shutdown in natural production?

And if so, what do you do then?


There is plenty of information of woman be given synthetic oxytocin during labor and their natural production is shut down. Obviously it is only temporarily, but if some meat head is doing this once a week, is there any info on possible side effects? Does anyone know what they would do if their natural oxytocin production was shutdown permanently?

Food for thought.
 
perceptionISprojection said:
cooool.......

Just couple simple questions.

Does anyone know if shooting this shit will cause shutdown in natural production?

And if so, what do you do then?


There is plenty of information of woman be given synthetic oxytocin during labor and their natural production is shut down. Obviously it is only temporarily, but if some meat head is doing this once a week, is there any info on possible side effects? Does anyone know what they would do if their natural oxytocin production was shutdown permanently?

Food for thought.
Click to expand...
I'm not sure, but I love the potential oxytocin has to make old muscles new again. Elasticity and pliability really gets reduced with age.
 
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