Oxytocin .... Intense orgasms!!!

[John Juan]

is the half life really a few minutes up to 15min??? i've heard a few stories that this stuff is used to induce labor (it's used for A LOT of things actually) but, has to be re administered every 15-20 minutes, and thats using higher doses... it only makes sense that for social anxiety/interactions. or, even using for sex it would have to be injected again. on the plus side. if that half life is true. it would kick in pretty damn fast, right?

no one really talks about the dose that is used, and for what reason on here. just mention dreams. it's not just you guys, other boards do it too.
kinda sounds like you're injecting the feeling you get after you rub one out, and you're just relaxed for a few and that's it.

pretty crazy that it's used for abortion. is that just for a comfort/bonding feeling to help the person mentally cope. or does it actually aid in skilliting of the fetus process?

i have so many questions about it's effects with gyno and tren lactation hahaha

I feel it all night long. It hits less than a minute after inject. I get very hot and flushed. Then I want to lie down. Sometimes I get horny and wack off. I always have vivid dreams and often wake up talking not knowing if I'm actually dreaming or in reality. I feel like I could sleep forever but once I get going I feel great at work.
I'd love to try it with a girl and cuddle fuck all night.

 

[wootoom]

Hmmm I have dreams of plane crashes constantly

 

[wootoom]

Are there long term effects of this?

 

[John Juan]

Are there long term effects of this?

The following study was conducted in a rodent who typically mates for life with one partner of the opposite sex. This type of rodent is often used in studies as it is very similar in social behavior to that of humans. Long term oxytocin use caused the male rodent to stray from it's monogamous normalcy and seek out some "strange" female ass.


Chronic intranasal oxytocin causes long-term impairments in partner preference formation in male prairie voles.

AuthorsBales KL, et al. Show all Journal
Biol Psychiatry. 2013 Aug 1;74(3):180-8. doi: 10.1016/j.biopsych.2012.08.025. Epub 2012 Oct 16.

Affiliation
Comment in
Biol Psychiatry. 2013 Aug 1;74(3):160-1.
Abstract
BACKGROUND: Oxytocin (OT) is a hormone shown to be involved in social bonding in animal models. Intranasal OT is currently in clinical trials for use in disorders such as autism and schizophrenia. We examined long-term effects of intranasal OT given developmentally in the prairie vole (Microtus ochrogaster), a socially monogamous rodent, often used as an animal model to screen drugs that have therapeutic potential for social disorders.

METHODS: We treated voles with one of three dosages of intranasal OT, or saline, from day 21 (weaning) through day 42 (sexual maturity). We examined both social behavior immediately following administration, as well as long-term changes in social and anxiety behavior after treatment ceased. Group sizes varied from 8 to 15 voles (n = 89 voles total).

RESULTS: Treatment with OT resulted in acute increases in social behavior in male voles with familiar partners, as seen in humans. However, long-term developmental treatment with low doses of intranasal OT resulted in a deficit in partner preference behavior (a reduction of contact with a familiar opposite-sex partner, used to index pair-bond formation) by male voles.

CONCLUSIONS: Long-term developmental treatment with OT may show results different to those predicted by short-term studies, as well as significant sex differences and dosage effects. Further animal study is crucial to determining safe and effective strategies for use of chronic intranasal OT, especially during development.

Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

 

[zero_net]

Can one insufflate oxytocin. ?

 

[mustang_00]

it's used for milk let down in live stock. what would the effects be on gyno prone people or even prolactin issues from tren. if any?

 

[John Juan]

it's used for milk let down in live stock. what would the effects be on gyno prone people or even prolactin issues from tren. if any?

Not sure. I don't get prolactin sides from progesterone derivatives, whether it be tren, deca, MENT, etc.. I haven't noticed any negative sides from researching oxytocin.

 

[John Juan]

Can one insufflate oxytocin. ?

Yes

 

[Elvia1023]

Not sure. I don't get prolactin sides from progesterone derivatives, whether it be tren, deca, MENT, etc.. I haven't noticed any negative sides from researching oxytocin.

It does surprise me the amount of guys who think 200mg deca/tren will give them prolactin gyno.

I can't comment on the long term effects but I haven't read about anything bad so far.

 

[John Juan]

Interactions between dopamine and oxytocin in the control of sexual behaviour.

AuthorsBaskerville TA, et al. Show all Journal
Prog Brain Res. 2008;170:277-90. doi: 10.1016/S0079-6123(08)00423-8.

SAffiliation
Abstract
Dopamine and oxytocin are two key neuromodulators involved in reproductive behaviours, such as mating and maternal care. Much evidence underlies their separate roles in such behaviours, but particularly in sexual behaviour. It is generally believed that central dopaminergic and oxytocinergic systems work together to regulate the expression of penile erection, but relatively little is known regarding how they interact. Thus, this review aims to discuss neuroanatomical proof, neuromodulator secretory profiles in the hypothalamus and behavioural pharmacological evidence which support a dopamine-oxytocin link in three hypothalamic nuclei that have been implicated in sexual behaviour, namely the medial preoptic nucleus, supraoptic nucleus and paraventricular nucleus (PVN). We also aim to provide an overview of potential dopamine-mediated transduction pathways that occur within these nuclei and are correlated with the exhibition of penile erection. The PVN provides the most convincing evidence for a dopamine-oxytocin link and it is becoming increasingly apparent that parvocellular oxytocinergic neurons in the PVN, in part, mediate the effects of dopamine to elicit penile erection. However, while we show that oxytocin neurons express dopamine receptors, other evidence on whether dopaminergic activation of PVN oxytocin cells involves a direct and/or indirect mechanism is inconclusive and further evidence is required to establish whether the two systems interact synergistically or sequentially in the regulation of penile erection.a