Combatting gyno is different than preventing gyno. Most guys using reasonable doses of aromatizing compounds and taking either aromasin, femara, or arimidex experience no gyno or other estrogenic sides. I know guys with very low BF% that do well with using Nolvadex 20mg daily. The key is prevention. If you are using DECA, FINA, or anadrol, then you must be aware of prolactin/progesterone sides. These can be prevented with Dostinex or Winstrol. Treating existing gyno is another story. First, you need to discover the source--is it estrogen based or prolactin-based? Then you need to block the estrogen and reduce the blood levels of estrogen. If prolactin-based, you need to reduce your proalctin levels. Many people have had success using Nolvadex to treat their gyno. They add in an aromatase inhibitor (aromasin, femara, arimidex) to reduce blood levels of estrogen at the same time. To reduce blood levels of prolactin, they add in Dostinex. Anothe option to treat gyno is applying DHT cream/gel. Lastly, surgery is the ultimate option.