LGD-4033, suppression and bloodwork

[Bobby84]

Hello, apologies in advance for the long post but I think some of the things here are important when considering or using LGD-4033.

I have been taking LGD-4033 for the last 2 weeks. I was aware of the potential of this product to severely suppress natural testosterone production so I had blood work done before and planned on doing more every few weeks. Also using HCGenerate since day 1 to help naturally boost my test.

My plan was the following:

Weeks 1 - 8: 3mg LGD ED
Weeks 1 - 8: 5 caps HCGenerate ED
Weeks 8 - 12: 5 caps HCGenerate ES ED
Weeks 8 - 12: Nolva 10mg ED

Blood work on day 0 of cycle:
Total Test: 15.0 nmol/L (8.6 - 29.0)
SHBG: 34.5 nmol/L (17 - 66)
LH: 3.7 mIU/ml (1.7 -8.6)
FSH: 2.9 mIU/ml (1.5 - 12.4)

Blood work on day 14 of cycle:
Total test: 5.3 nmol/L (8.6 - 29.0)
SHBG: results due 8 September
LH / FSH: not done

So my test has already taken a massive hit after just 2 weeks on 3mg each day (even when taking HCGenerate which makes me doubt its effectiveness). I have a few questions I'm hoping people may have the knowledge to answer:

1) Why does LGD suppress my natural testosterone when I am not putting any testosterone into my body as per steroid use. I looked for answers on this point and no one could give a good answer. It makes sense with steroids as you're putting so much extra test in but why would the body lower production when it still needs it for things like libido etc.

2) My testosterone has lowered so much, why do I still feel exactly the same as before I started (libido same, my boys nice and plump, morning erections on occasion)? Surely I should feel the effect of such a cut in testosterone? Maybe HCGenerate is helping somehow?

3) What will happen if I continue until I finish the full 8 weeks? Will my test production go to 0 eventually and is that even a problem if I am planing a decent PCT? Will I feel terrible soon.

Thanks for any answers / advice.

 

[Oxbow-]

Hello,
1) Because your body regulates his hormones levels (homeostasis) via receptors. When taking clomid or nolvadex you make believe the receptors of estrogen there is no estrogen by exemple. And normally estrogen comes from testosterone so the body assumes there is not enough testosterone and it helps recovery.
Sarms are selective androgen receptor modulatir, serm selective estrogen receptor regulator.
So sarms make believe your body you are full of testosterone even if you are not. So it shut you down.

2) You wont see you have a lower test so easily. If you come from a huge test cycle and during pct you are 100% down yes with only the deca esther cleaning you will feel it hard. But not here.

3) google lgd studies they show the suppression and the come back. LOWER YOUR DOSAGE. And dont take lgd if you are not on trt.

Lgd-4033 should be taken on TRT IMO. A lot of people cruise and blast and lgd is for the cruising.

 

[Bobby84]

Thanks for your reply - that cleared up a few things i had been wondering about for a while.

Another thing that interests me is, will the natural testosterone eventually go to zero after a long enough time? Or would the testosterone only be reduced by the amount that it's no longer needed (for muscle growth) but would still be needed for other things eg energy levels, libido.

It's kind of hard to explain what I am asking, for example, before taking LGD my testosterone was being used for lots of things, one of them was to attach to androgen receptors and promote muscle growth etc. Since LGD is now taking that role, my body needs less test as its no longer needed to do that function BUT some test would still be needed to maintain energy levels and sex drive and erections etc. Or is the body not that clever and just thinks it has too much test (even though it doesnt) and will just go to zero eventually?

I just want some assurance that if i continue until the end of the cycle i wont feel like rubbish due to low libido and energy.

Thanks again

 

[Pepe Le-r3]

Oxbow, didn't you say the body regulates testosterone by estrogen conversion? So wouldn't suppression be due to androgen receptors being filled by the sarm, therefore higher circulating test, causing a greater conversion of free test to estrogen?

 

[j_p]

Oxbow, didn't you say the body regulates testosterone by estrogen conversion? So wouldn't suppression be due to androgen receptors being filled by the sarm, therefore higher circulating test, causing a greater conversion of free test to estrogen?

well although estrogen ofcourse plays a role, its more due to testosterone in males.
for example. you can take teste or even a SARM along with high doses of an AI keeping estrogen low or even crashed (i dont rec this ofcourse) and you would still be getting shut down. even with no estrogen and high test shutdown comes, so it is not that estrogen is high or low, but a combo of test and/or estrogen. If you get what i mean


also; using a sarm or other steroid that DOESNT have estrogen conversion and getting an anabolic effect from it doesnt necessarily mean you will have higher freetest/estrogen. it really depends on the conditions

 

[j_p]

Thanks for your reply - that cleared up a few things i had been wondering about for a while.

Another thing that interests me is, will the natural testosterone eventually go to zero after a long enough time? Or would the testosterone only be reduced by the amount that it's no longer needed (for muscle growth) but would still be needed for other things eg energy levels, libido.

It's kind of hard to explain what I am asking, for example, before taking LGD my testosterone was being used for lots of things, one of them was to attach to androgen receptors and promote muscle growth etc. Since LGD is now taking that role, my body needs less test as its no longer needed to do that function BUT some test would still be needed to maintain energy levels and sex drive and erections etc. Or is the body not that clever and just thinks it has too much test (even though it doesnt) and will just go to zero eventually?

I just want some assurance that if i continue until the end of the cycle i wont feel like rubbish due to low libido and energy.

Thanks again

toomany factors and toomany differences person to person to say.
the longer on aas the harder the shut down will be per that compound, but toomany factors... one person may have small amounts of test being made after being on aas for a year where another may be completely shut down and sterile. it really is an individual thing you would have to find out for yourself.

 

[Bobby84]

Thanks guys i think we are getting there.

One last thing. So when taking testosterone as an example, the person will feel great, good mood, lots of energy (all the effects of having high test). The person's natural test production will eventually shut down but that person will still feel fantastic as he has very high test being injected!

As I wont be taking any extra test during my LGD cycle, will i feel the effects of low test eventually or is the LGD somehow acting like test?

Can anyone who has done a 6+ week cycle of LGD only please chip in with how they felt during the cycle?

Thanks

 

[spursmad]

Hi I ran lgd for 8weeks in did not shut me down I was 99.6% pure what did you use?

 

[Bobby84]

Hi I ran lgd for 8weeks in did not shut me down I was 99.6% pure what did you use?

You say it didn't shut you down, do you mean you were suppressed but not fully shutdown (i.e. test levels = 0 from bloodwork)? The clinical trials and lots of bloodwork show that it has significant effect on test levels.

I have no idea how pure my stuff is, it's DNA Anabolics LGD-4033 (google search brings it up).

 

[carlsjr]

Your lh and fsh were in critical condition before you began. I've ran it at 10mg for 8 weeks with minor suppression.

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