IGF - Would you do it?

[drrman]

19. like i said bro, it all depends on goals. i wish i wouldnt have to run those doses, but if i have to i will. unless it compromises my health.



O i know bro, i never said it was. i just said. IF i was to use igf, i wouldnt run small doses.

so you have never run IGF at all and you are giving advice on it....also you dont' think 4g of juice a week will compromise your health at all????

you have not tried, experienced, researched any of the shit you are talking about.....so why even bring it up?

 

[drrman]

Finally another bro, backing me! I know we dont agree on the IGF1, but doing stupid shit like 200mcg/day, 20ius rHGH, and 10ius slin is ridiculous.. The dude is like 20 years old..

This fucker has no business even posting advice/ideas like this when he doesn't even know what he is talking about.....im sure he has no clue as to how to even use insulin, much less insulin WITH igf

guess he doesn't know the IGF will make the insulin twice as potent at 100mcg...so at 200mcg with 10ius of insulin he would most likely die!

 

[ItalianMuscle27]

This fucker has no business even posting advice/ideas like this when he doesn't even know what he is talking about.....im sure he has no clue as to how to even use insulin, much less insulin WITH igf

guess he doesn't know the IGF will make the insulin twice as potent at 100mcg...so at 200mcg with 10ius of insulin he would most likely die!

Like I said bro, I know about insulin. And when I see people posting stupid shit and giving advice like that, it pisses me off. Let the a*swipe do what he wants to himself, dont advise others todo the same..especially when he has never even used it.

 

[dugie65]

Go ahead and do it, and let me know how it works out for ya..

Still waiting for why you think IGF will compromise your health further down the line.

 

[drrman]

Still waiting for why you think IGF will compromise your health further down the line.

i think he was referring to the guy that mentioned taking all the slin/hgh/igf and 4g gear bro....telling him to go ahead and try his combo...not speaking to you about trying igf

 

[dugie65]

You need to relax a little..20ius of gh and 10ius of slin? Your just asking for trouble.. You must not have researched slin enough, its overrated and dangerous.. One, you could become diabetic, or even worse death! IGF1 isnt even approved and probably never will be! Ive used it, and its a waste of money! Im just waiting for the reports to come back on this stuff 5-10 years from now, and I dont think it will be good..

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I was refferring to this comment.

 

[ItalianMuscle27]

Still waiting for why you think IGF will compromise your health further down the line.

Heard of the condition, diabetic? There is your answer..

 

[Phys PhD]

it CAN speed up cancer growth ONLY IF you have it. it will NOT cause cancer. and yes i would use it, but at 200mcgs and up. lower than that its not worth it IMO.

This is ridiculous. If you guys want to know about the effects of IGF-1, check out "www.pubmed.com" and enter "IGF-1" "skeletal muscle." This research has been going on for years. Locally injected IGF-1 has an extremely short half-life and putatively will not have systemic effects.

As far as the cancer properties go, this gets a bit dicey--it activates hypertrophic signals within skeletal muscle cells (specifically, the PI3 kinase-Akt pathway) and down-regulates degradation pathways (FoxO among others). To get at your question, from what I've seen no research has been done on local IGF-1 administration and increased risk of cancer.
I speculate that IGF-1 will induce proliferation in other cell types within the muscle that is being injected--fibroblasts, muscle pre-cursor cells, etc.--such a cancer risk is possible. However, your body produces local IGF-1 after heavy lifting and I have yet to hear about an association between weightlifting "muscle tumors." Nor have I heard of professional bodybuilders being diagnosed with tumors in their muscles. This is anecdotal evidence, but there is nothing else out there currently.

Oh, and by the way, we have cancer cells in our bodies ALL THE TIME. Our immune systems recognize these cells and destroy them--this is going on everday. So, saying "only if you have cancer" is not a viable argument.

 

[dugie65]

This is ridiculous. If you guys want to know about the effects of IGF-1, check out "www.pubmed.com" and enter "IGF-1" "skeletal muscle." This research has been going on for years. Locally injected IGF-1 has an extremely short half-life and putatively will not have systemic effects.

Is this IGF-1 LR3 or just IGF-1?

 

[supra5469]

Is this IGF-1 LR3 or just IGF-1?

According to this I beleive he is reffering to IGF-1

The most effective form of IGF is Long R3 IGF-1, it has been chemically altered and has had amino acid changes, which cause it to avoid binding to proteins in the human body and allow it to have a much longer half-life, around 20-30 hours. "Long R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substation of an Arg(R) for the Glu (E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. This analog of IGF-1 has been produced with the purpose of increasing the biological activity of the IGF peptide."

"Long R3 IGF-1 is significantly more potent than IGF-1. The enhanced potency is due to the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF's."