I think a lot of it has to do with personal goals and where your family actually is!
If your family is set and financially would be Ok if you dropped dead of a heart attack compared to a family that is dependent on you as a bread winner could definitely affect how you look at and use steroids.
Also what are your goals are you looking to get a nice physique or are you dreaming of shredding down and getting that magazine shape for whatever the reason.
Most over 40's would do best to just do testosterone and maybe run a blast now and then. Maybe in a cut run a little Anavar. With that said some of us want more and well to be honest I have not felt as good as I did on Tren when taking any other steroid. If you have never taken tren I would say stay away from it, cause the way you feel while on it can make you want it again and again and again just like any other druggy.