For me it honestly depends on the machine. I prefer using a leg press machine to do my calves since it supports my entire back not just the lower back. With just a seated calf press (the machine i dont like) i am pumping 550 lbs easy but it hurts my lower back since all the weight is concentrated there. But on the leg press machine where i can focus the bulk of the weight onto the rest of my back and shoulders i am just grazing 1000 (22x45 lbs plates plus a small bit of body weight). I have enormous calves do to my job in the navy, running up and down 60degree ladderwells. I only weigh in at 185. I can put up the 1000 around 12 times full ankle rotation, after that it begins to get hard to get the full extension. it might help to say that i used to weigh 200 so that extra wieght both hurt and helped me develop my calves. Currently i have laid off calves and legs to preportionalize my body a bit more. But if anyone needs help conditioning their calves. I suggest for bulk. High weight 8 sets of 5 reps with around 2-2.5 ur body weight. When u do your calf raises change the angle of ur ankle in relationship to eachother. 4 sets straight toe, 2 sets pigeon toed and 2 sets with ur feet at a 45 degree angle....Once u finish this Go through it agian drop 20% of ur weight and goto failure on all three positions.
For toning, ur muslces use weight equal to ur body weight, 5 sets of each position 12 times for a total of 180 reps. then drop half the weight and do it all over agian, Finally finish with a goto failure on each position.
This worked for me and now i have a very nice groove going right up the middle of my calves.