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ER papers from friends liver problem ( jaundice).
- Thread starter chazk
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S
Spartacus
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liver enzymes 101
Alanine aminotranferease (ALT) and aspartate aminotransferase (AST) are enzymes located in liver cells that leak out into the general circulation when liver cells are injured. These two enzymes were previously known as the SGPT (serum glutamic-pyruvic transaminase) and the SGOT (serum glutaic-oxaloacetic transaminase). These two transaminase enzymes may be reported on lab slips with both their new names and previous names or by their newer names only. ALT and AST are present in highest concentrations in cells from the liver, heart, skeletal muscles, and red blood cells. Patients whose LFTs show a predominant rise in the transaminases have liver diseases that are characterized by hepatocellular damage.
ALT is found predominately in the liver, with lesser quantities found in the kidneys, heart, and skeletal muscle. As a result, the ALT is a more specific indicator of liver inflammation than the AST, as the AST may also be elevated in diseases affecting other organs, such as the heart or muscles. The AST is also elevated after a myocardial infarction, and during acute pancreatitis, acute hemolytic anemia, severe burns, acute renal disease, musculoskeletal diseases, and trauma. Because intramuscular (IM) injections cause muscle trauma that may release AST and ALT into the bloodstream, IM injections should be avoided before LFTs are done. If an IM injection must be given close to the time blood for LFTs is drawn, the nurse should indicate on the lab slip the time the injection is given. Many liver enzyme tests are also affected by medications. It is important to consult the laboratory manual for medications that should be considered in the interpretation of test results, and to indicate such medications on the lab slip.
http://rnceus.com/lf/lfast.html
Alanine aminotranferease (ALT) and aspartate aminotransferase (AST) are enzymes located in liver cells that leak out into the general circulation when liver cells are injured. These two enzymes were previously known as the SGPT (serum glutamic-pyruvic transaminase) and the SGOT (serum glutaic-oxaloacetic transaminase). These two transaminase enzymes may be reported on lab slips with both their new names and previous names or by their newer names only. ALT and AST are present in highest concentrations in cells from the liver, heart, skeletal muscles, and red blood cells. Patients whose LFTs show a predominant rise in the transaminases have liver diseases that are characterized by hepatocellular damage.
ALT is found predominately in the liver, with lesser quantities found in the kidneys, heart, and skeletal muscle. As a result, the ALT is a more specific indicator of liver inflammation than the AST, as the AST may also be elevated in diseases affecting other organs, such as the heart or muscles. The AST is also elevated after a myocardial infarction, and during acute pancreatitis, acute hemolytic anemia, severe burns, acute renal disease, musculoskeletal diseases, and trauma. Because intramuscular (IM) injections cause muscle trauma that may release AST and ALT into the bloodstream, IM injections should be avoided before LFTs are done. If an IM injection must be given close to the time blood for LFTs is drawn, the nurse should indicate on the lab slip the time the injection is given. Many liver enzyme tests are also affected by medications. It is important to consult the laboratory manual for medications that should be considered in the interpretation of test results, and to indicate such medications on the lab slip.
http://rnceus.com/lf/lfast.html
chazk
New member
Spartacus said:
thanks spart thats great info ...
yea your right I mentioned at the bottom of the last repley he has some inflamation in his gallbladder dont know exact he just said a duct or something..so that was prob the main culprit not really the liver itself..
also do steroids inflame the gallbladder? or was it more of a genetic thing combined with steroids
S
Spartacus
Guest
LFT=liver function test aka liver panel
solidspine
New member
What caused his liver problems are you implying gear caused his liver problems?
chazk
New member
high bilirum the product of rapid redblood cell death and a inflammed gallbladder..cuased itsolidspine said:
doctors told him had he not been on steroids cuasing a high redbloodcell count he would not have had the high bilirum cuasing the jaundice reguardless of alittle inflamation in his gallbladder becuase its not clogged by any stones but a little inflamed
so not really liver damage more like liver could not handle the load of bilirum and the gallbladder had a inflamed duct..pushed the bilirum back into his blood stream and came out in his skin and eyes
i'm gonna have him ask his doctor if the ba/ba and peg soultions in the steroids could have been the culprit to the inflamation of the gallbladder ducts and some stress on the liver..
he is no longer taking steroid for two weeks and the bilirum is comming down..
so the stroids had something to do with the bilirum ...if not he would be the same unchaged
solidspine
New member
That is a shame I hope he get better fast, liver problems are not funny.
perp69
New member
Only thing really outrageous is the bilirubin, which could have caused the symptoms he had. Yeah, his LFT are slightly high-no biggie. RBC slightly high-again not that bad. Really labs don't look that bad except for bilirubin. If he was producing a lot of RBC's then possible his liver couldn't handle the extra load from the them breaking down thus increase bili. Tell him don't wait so long to go to the doc next time.
Perp
Perp
chazk
New member
I hope so to ..he went from 215lbs down to 193lbs in 3 weeks prob lost all his gains and then some....now he is depressed . I hope he bounces back soon he is not cleared to lift weights untill may 1st and thats only if he recovers by then doc said could take up to 2 monthssolidspine said:
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