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napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Eating Rubber With a 22 Gauge

That means the needle is bad, or is not an intradermal/IM bevel. A biopsy needle, for instance, is designed to do exactly what you're describing as happening to the rubber stopper. I have the easiest time getting 16g and 18g needles, so I use those for drawing, and never had a bit of rubber. Even if the rubber on your vials is weird or poor quality, a hypodermic needle shouldn't core out any of it. Look closely at the tip of the needles you were using to draw, and see if the bevel is steeper than your 25s. If so, you got a batch of special-purpose needles. A regular hypodermic needle with IM or intradermal bevel, should make a straight slit cut when put through thin rubber. If it's a funny shape; a triangle or is a roundish hole, it's not the right kind of needle.

Charles
 
That means the needle is bad, or is not an intradermal/IM bevel. A biopsy needle, for instance, is designed to do exactly what you're describing as happening to the rubber stopper. I have the easiest time getting 16g and 18g needles, so I use those for drawing, and never had a bit of rubber. Even if the rubber on your vials is weird or poor quality, a hypodermic needle shouldn't core out any of it. Look closely at the tip of the needles you were using to draw, and see if the bevel is steeper than your 25s. If so, you got a batch of special-purpose needles. A regular hypodermic needle with IM or intradermal bevel, should make a straight slit cut when put through thin rubber. If it's a funny shape; a triangle or is a roundish hole, it's not the right kind of needle.

Charles

Thanks for the info ^

My 22 gauge pins are definitely the right ones for IM injection. They are the same brand, BD, as the 25's I usually use. They look exactly the same as the 25's except for that the needle itself is bigger.

I live in one of the driest places in the US in terms of humidity. I always wipe my stopper and vial with alcohol before using. I'm wondering if the combination of low humidity and exposure to alcohol caused this to happen.
Any thoughts on this?
 
Maybe the vial sat upside down for an extended period of time. The stopper could have maybe absorbed some oil and got "soggy" or broken down.
 
I live in one of the driest places in the US in terms of humidity. I always wipe my stopper and vial with alcohol before using. I'm wondering if the combination of low humidity and exposure to alcohol caused this to happen.

Any thoughts on this ^ ?
 
draw the whole lot into a barrel with whatever size then push it through i filter into another vial. problem solved
 
I've heard this often. Anything thicker than a 23g has the possibility of releasing small chunks of black rubber butyl into your vial..You can use a smaller pin to draw it up or just avoid any chunks you cause. They will sink because they're heavier than the oil. Our rubber stoppers aren't old and they're as rubbery as they should be and if you keep stabbing them with a 21g, some rubber is bound to chunk off.
 
Thanks for the info ^

My 22 gauge pins are definitely the right ones for IM injection. They are the same brand, BD, as the 25's I usually use. They look exactly the same as the 25's except for that the needle itself is bigger.

I live in one of the driest places in the US in terms of humidity. I always wipe my stopper and vial with alcohol before using. I'm wondering if the combination of low humidity and exposure to alcohol caused this to happen.
Any thoughts on this?

I'm stumped... The only other thing I can think of, would be that the stopper is deteriorated or of a bad material. I have a nearly-empty vial now, and as soon as it's empty, I might try to mess with it and see if I can make this happen, and if so, I'll maybe have an idea. I have needles up to 8g, so if those don't cause it, all I can say is that your vials may have faulty stoppers.

Charles
 
Thanks bros for all the feedback and thanks for the info on filters.

The injection site I used after drawing the last ML from that vial was a bit more sore than usual 2 days after injection. But this soreness is gone by now. I'm thinking that maybe all the stabbing with the 22's caused a small piece of rubber to enter when I drew with a 25.

O well... That vial is empty now and it's on to the next delicious vial of Test :)
 
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