Does Aspirin inhibit protein synthesis?

[John89231]

I'm about to run an ECA stack for my cutting diet. Im worried about the Aspirin effecting my protein synthesis so I just might cut it out of the stack. What do you guys think is the aspirin needed in the stack? How much? Or should I take it out?

 

[KenBraggofCarroltonGA]

never heard of that one

 

[wolfman87]

if i remember correctly it thins the blood out which in turn does something else.... lol i'd have to go dig up where i think i read that and i still gotta go to the store so maybe later bro.

 

[Nelson Montana]

No, but because it's an anti inflamatory there's some speculation that may inhibit muscle growth though I doubt a couple now and then is going to make any difference in the big picture. Take aspirin only when you really need it. An amazing drug.

 

[goin on 4T]

It does impede muscle growth/development. Fact not fiction.

 

[John89231]

Really so should I just skip it and take it out of my ECA stack?

 

[jokerswild]

Don't know about halting gains, i'm gaining like a mofo and i'm taking 81mg asprin every morning, along with 40mg of dbol, one thing I did notice is that you bruise alot easier while on a daily asprin....

 

[79steeler]

I take an aspirin everyday 325mgs, and I have noticed no loss in gains, or any other side effect for that matter. This is doctor ordered. Ive made great gains this year, so for me aspirin does not seem to have any effect on my gains.

 

[lookinfit75]

I take a full aspirin fairly regularly (maybe one EOD on average) and have not noticed any size/strength lose. Maybe this happens at higher doses, the muscle loss that is. Since it does thin out the blood be careful with the bruising and cuts.

 

[John89231]

So what exactly does it help in the ECA stack.

 

[goin on 4T]

caffine dialate the blood vessels
aprin thins the blood
ephedrine speeds up the heart

 

[lookinfit75]

caffine dialate the blood vessels
aprin thins the blood
ephedrine speeds up the heart

You sure about that? Last I heard was that caffeine is a vaso-constrictor which is why it raises blood pressure, right? If it (caffeine) dilated blood vessels then someone with hypertension or ED would be able to take a caffeine supp to help with their issues.

 

[KenBraggofCarroltonGA]

You sure about that? Last I heard was that caffeine is a vaso-constrictor which is why it raises blood pressure, right? If it (caffeine) dilated blood vessels then someone with hypertension or ED would be able to take a caffeine supp to help with their issues.

u are correct. i can't beleive this thread is still poppin

 

[goin on 4T]

What you are looking for from why you take an ECA stack is Vasodialation. However it is a vasoconstrictor also but in an different area. Read for yourself.

Caffeine's mechanism of action involves increasing the synthesis and release of catecholamines and increasing intracellular cAMP concentration through phosphodiesterase inhibition. These pharmacological effects are demonstrable in multiple organ systems. Central nervous system physiological responses include stimulation of the cerebrum and medulla, resulting in the often desired effect of alertness and hypervigilence. The cardiovascular response includes direct stimulation of the myocardium; however this effect may be mitigated to some extent by concurrent vagal stimulation. These factors sometimes result in ventricular irritability, manifested as premature ventricular contractions. Likewise, direct vasodilation occurs, although this may be counteracted by vasoconstriction from stimulation of the medullary vasomotor center, and may cause either increases or decreases in blood pressure. Smooth muscle is relaxed by caffeine, while skeletal muscle is stimulated.

 

[Dial_tone]

Wow, some of you guys worry about the most minute shit. I wonder how many oz of muscle this has cost me over the last 25 years...

 

[MsBeverlyHills]

heres an old thread on protein sythesis & the effects of ibuprofin, aspirin or Naproxen Sodium-

http://www.elitefitness.com/forum/w...ting/taking-advil-before-training-246049.html

 

[lookinfit75]

What you are looking for from why you take an ECA stack is Vasodialation. However it is a vasoconstrictor also but in an different area. Read for yourself.

Caffeine's mechanism of action involves increasing the synthesis and release of catecholamines and increasing intracellular cAMP concentration through phosphodiesterase inhibition. These pharmacological effects are demonstrable in multiple organ systems. Central nervous system physiological responses include stimulation of the cerebrum and medulla, resulting in the often desired effect of alertness and hypervigilence. The cardiovascular response includes direct stimulation of the myocardium; however this effect may be mitigated to some extent by concurrent vagal stimulation. These factors sometimes result in ventricular irritability, manifested as premature ventricular contractions. Likewise, direct vasodilation occurs, although this may be counteracted by vasoconstriction from stimulation of the medullary vasomotor center, and may cause either increases or decreases in blood pressure. Smooth muscle is relaxed by caffeine, while skeletal muscle is stimulated.

So according to this explanation there is some vasodilation that occurs but it is counter acted by vasoconstriction from stimulation so the end result is vasocostriction either way you look at it. So in the end, caffeine does cause vasoconstriction.