Do You take it in the ASS?

[gimp]

The only real benefit to shooting in larger muscle groups, like your quads and glutes is that generally you can safely shoot upto 3 cc's. In smaller muscles (relative to your body) the general rule is to not shoot more than 1 cc. These are general guidelines for "normal" sized people, obviously you can increase the cc ratio the larger you are.

 

[SaltyOlPirate]

The only time I inject in my glute is when someone is doing it for me. I can't safely inject, aspirate and keep my hands still while injecting my own glute. But I've heard the same thing in regards to absorption in the glutes.

 

[SUST-MAN]

Another Armenian! hehe......

 

[gimp]

I don't even bother aspirating, it's useless.

 

[acneman]

dont say that gimp.

nandi 12 posted a study on the glute vs site issue ill try to find it

 

[acneman]

opps jguns not nandi

http://boarnbull.com/showthread.php?s=&threadid=1178

Glute shots with oil based steroid MOST effective
Here is an interesting study that I found a few months ago:

Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: effects of ester, injection site and injection volume.

Minto CF, Howe C, Wishart S, Conway AJ, Handelsman DJ.

Department of Anaesthesia and Pain Management, Royal North Shore Hospital, University of Sydney, Australia.

We studied healthy men who underwent blood sampling for plasma nandrolone, testosterone and inhibin measurements before and for 32 days after a single i.m. injection of 100 mg of nandrolone ester in arachis oil. Twenty-three men were randomized into groups receiving nandrolone phenylpropionate (group 1, n = 7) or nandrolone decanoate (group 2, n = 6) injected into the gluteal muscle in 4 ml of arachis oil vehicle or nandrolone decanoate in 1 ml of arachis oil vehicle injected into either the gluteal (group 3, n = 5) or deltoid (group 4, n = 5) muscles. Plasma nandrolone, testosterone and inhibin concentrations were analyzed by a mixed-effects indirect response model. Plasma nandrolone concentrations were influenced (P < .001) by different esters and injection sites, with higher and earlier peaks with the phenylpropionate ester, compared with the decanoate ester. After nandrolone decanoate injection, the highest bioavailability and peak nandrolone levels were observed with the 1-ml gluteal injection. Plasma testosterone concentrations were also influenced (P < .001) by the ester and injection site, with the most rapid, but briefest, suppression being due to the phenylpropionate ester, whereas the most sustained suppression was achieved with the 1-ml gluteal injection. Plasma inhibin concentrations were also significantly influenced by injection volume and site, with the lowest nadir occurring after the nandrolone decanoate 1-ml gluteal injection. Thus, the bioavailability and physiological effects of a nandrolone ester in an oil vehicle are greatest when the ester is injected in a small (1 ml vs. 4 ml) volume and into the gluteal vs. deltoid muscle. We conclude that the side-chain ester and the injection site and volume influence the pharmacokinetics and pharmacodynamics of nandrolone esters in an oil vehicle in men.

Basically, this study shows that Nandrolone is most bioavailable when shot in the glutes vs. deltoid region. It also shows that the higher the concentration of steroid, the more bioavailable it is. Interesting information for those of you that rotate sites (I do). This study would not be limited to nandrolone, it would basically work the same with any oil based steroid. The moral of this story is that you want the highest MG/ML steroid, and you want to shoot in the glutes.
I used to have an expanded version that actually showed how much of a difference in bioavailablity in the glutes vs. delts and it was pretty significant. I'll have to look for that.
Food for thought.

http://jpet.aspetjournals.org/content/vol281/issue1/images/large/pt0374778001.jpeg

 

[mike13555]

gimp: "I don't even bother aspirating, it's useless."

u wont say that when u shoot in a vein and pass out

 

[acneman]

nandi12's thoughts on it plus the study abstract


The result seems counterintuitive at first, but actually makes sense. First, ignoring what is going on and just analyzing the data, the authors conclude that glute injections have a higher bioavailability because the so called "area under the curve" (AUC)for the glute injection is larger than for the delt.

It's easier to see from the smaller diagram (Fig 1) at

http://jpet.aspetjournals.org/cgi/content/full/281/1/93

This is how bioavailability is measured in pharmacology. AUC is just a measure of the total amount of the drug that was in your system over the lifetime of the drug.

It is obtained by numerically integrating the plasma concentration vs. time curve. (All that calculus they made you take is actually good for something.)

Why is the AUC for the glute site larger than for the delt? The authors conclude that blood flow to the delt is greater, and there is less fat for the drug to hide in. So the drug is released into the system faster than from the delt. It turns out that the elimination rate for any drug is proportional to the concentration of the drug. So the drug is diffusing out of the delt faster, raising the plasma concentrations, and increasing the clearance rate.

That's a good question about water based steroids. The ones BB generally use are winstrol and test suspension. Both of these are suspensions and not solutions. The problem with suspensions is if the vehicle (water) leaves the injection site too quickly, the drug can precipitate out in the depot site and become unavialable.
This seems like more of a possibility in the delt because of the higher blood flow.

The studies I have seen for actual water based solutions show greater bioavailability from the delt, but I really don't know what to think about suspensions.

 

[gimp]

I don't disagree with site injects. I just don't know how effective they are. I've only done one cycle and used my quads and glutes. Do you guys who site inject notice a difference.

 

[acneman]

you know i should have taken credit for finding that myself who would have known