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DNP theory

K, I would take Roy's word on this. This dude is a fucking chemical wizard, goes by the name "moon face" around teh labs here at the uni. If you do not blieve insecticide (dnp) is a poision, you are a fuckin homo cheesecake eater, no bullshit/
 
the reason DNP works as a pesticide is because insects dont dissipate heat like we can, so they have no real way to cool off when their temp goes up. We radiate heat and sweat, so DNP doesnt have the same detrimental effects as it does on insects.
DNP passed the AMES test. It is basically "safe" if used correctly. There are a few studies on its uses for fat loss (even a few recent ones). I dont think its a posion if used properly and im not a homo. Just because a bro is a chemical wizard dont mean shit. My micro teacher (also a masters in bio and o chem) is a brilliant mutherfucker, but he thinks AAS can cause brain cancer. DNP basically changes the way we are able to create ATP, through the ETC.
 
Simple: Poison=Toxic=Bad, if not used properly. Thats the point im trying to make here. And yes it does change the way we are able to create ATP, by basically making it so that the body shuts down the process of chemiosmosis. That in turn consumes all fuel molecules, including stored fuel. So you end up getting onlt 4 ATP per glucose molecule in a given cell, explaining your absolutely exhausted state. Normally you get around 34-38 ATP per cell. And all this burnt energy will be lost as heat, explaining the tremendous sweating that occurs. So there you have it, use in moderate doses and you should be alright...

Roy
 
thanks bruthas

lots of great info here....I been doin gmy research on this, I just thought maybe my theory could be possible.....Andy to answer your question, to explain what I was trying to do, i guess in lame-mans tems i was thinking since DNP is similar to exercise, makin gyou exert more enrgy for everything you do, I was thinking of applyiong a yohimbine solution topically to my chest and love handles o see if it owuld free up fat to burn from t hose areas....the same as one would do normally except id be substituting dnp for cardo..I udnesratnd yor point though trhat its active in the muscle cells, I wsnt aware of the specifics...thanks again guys:)
 
lol twitched! :D I agree as well. If you want real fat loss, DNP works wonders. Use it correctly and add only the needed vitamins, and you dont need anything else.
 
decadense said:
Yes but I'd imagine DNP could trigger cancer. Generates massive amounts of free radicals, apparently. Free radicals damage every part of the body including DNA.

Yes, but do yo uknow what it means to say that DNP "generates" free radicals? That means that the free radicals stored in fat are released in a sudden surge from accelerated fat burning. That means you're releasing the same amount of free radicals from DNP that you'd release form "normal" fat-burning, except that it's in a briefer period of time.

That might still sound like a bad thing, because even though the sum totals are the same it's not good to swamp your body with FR's. But on the other hand, people who use DNP are also FAR more attentive to using antioxidants at that time, too, such as massive doses of vitamins E and C, ALA, green tea, NAC, fruit, etc. Which may mean you're actually protecting your body more carefully against those radicals than when we take a looser more "natural" approach with an ECA and cardio.



Okay, now here's MY theoretical question: if DNP acts on ATP, and Ribose supplements enhance ATP production, what would happen if you used ribose and DNP together? Would it minimize the effects of DP by restoring the ATP that DNP is trying to uncouple, acting like a sort of "antidote" for DNP, or would it improve the function of DNP by enhancing energy and muscle function, which promotes superior workouts and recovery, thus more total exercise?
 
Re: Re: Re: DNP theory

Primal X said:


So you're saying the weight you lose on DNP is muscle and not fat?

No, quite the contrary. That means DNP *helps* muscle to accelerate fat burning. DNP is remarkably anti-catabolic, and by increasing the number and activity is intramuscular mitochondrion, it spares muscle resulting in 95% of weight lost coming from fat. In fact, people often enjoy an "anabolic rebound" when going off DNP as their mitochondria-rich muscle cells are primed for amazing spurtsw of growth.

DNP is amazing stuff. It's Ames-negative, and non-toxic to the liver, kidneys, and cardiovascular system. Contrary to T-mag's lunatic warnings, it does NOT raise core body temperature putting you at risk for "melting your organs" (or whatever bullshit sci-fi propaganda they wrote about it), or "burning your brain." DNP raises surface temperature only, and by a very SMALL degree (but which feels like hell to the person who'd swear they have a fever of 110!).
 
Roy said:
. And yes it does change the way we are able to create ATP, by basically making it so that the body shuts down the process of chemiosmosis. That in turn consumes all fuel molecules, including stored fuel. So you end up getting onlt 4 ATP per glucose molecule in a given cell, explaining your absolutely exhausted state. Normally you get around 34-38 ATP per cell. And all this burnt energy will be lost as heat, explaining the tremendous sweating that occurs
Roy

Chemical Wizard??? lol... Have a seat on the bus...

Here's part of a thread I started.. I urge you to check out the rest of it.... If you cannot access it, buy a platinum membership.


http://boards.elitefitness.com/forum/showthread.php?s=&threadid=71780&highlight=DNP


Hopefully this will clear up some misinformatio on DNP.


Even on high dose of DNP, the majority of ATP is STILL made via oxidative phosphorilation. A lot of people think that DNP completely eliminates oxidative phosphorilation and that cellular ATP synthesis relies exclusively on substrate level phosphorilation. Actually though, DNP just makes oxidative phosphorilation a LITTLE less efficient. ATP levels in cells really don't change that much. Previously in many biochemistry books, ATP is listed as an important metabolic regulator. In reality, ATP isn't an important regulator since the energy charge of a cell doesn't change all that much. What IS an important metabolic regulator is AMP. And what DNP does do is keep AMP levels high enough to keep green lights going on all glycolytic and TCA enzymes.

Incedentally, the high AMP levels inhibit glycogen synthesis in liver as well as muscle. This means that glucagon and epinephrine dominate over insulin. While this is great for fat loss, it isn't so great for muscle preservation since glucagon also stimulates the liver to make glucose out of amino acids (gluconeogenesis) derived from muscle tissue. Hence DNP being "anti-proteolytic" isn't a great assumption.

DNP does not directly stimulate muscle breakdown however the effects that it causes in the body certainly promote muscle breakdown. I might also add that the causes of death from DNP is not a result of low ATP but, rather, from the extreme heat that DNP causes.

As far as limiting factors with DNP and fat loss, well, there aren't any. In a test tube with mitochondria, oxygen becomes the limiting factor. However this is not the case in vivo since the levels of DNP used for the in vitro tests are far beyond what would be lethal in a human body.


Andy
 
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