OK, What are her goals, her current height, weight, %bf, training and diet history, etc....
Is she taking estrogen because of postmenopausal symptoms, and if so, what are her symptoms? Is she a bodybuilder, or just a chick looking to lose some flab? What kind and how much estrogen is she taking. In premenopausal women, taking enough AAS will affect the HP axis enough to reduce ovarian estrogen production, but the anavar will not have much effect on dietary (supplemental) estrogen. In other words, the anavar cannot shut down her production of excess estrogen because it's not under the control of her hypothalamus/pituitary feedback regulatory system. Taking Nolvadex is just plain silly in this situation. So please tell us a little more about why she is taking this combo of drugs and what she hopes to achieve.