^ Coming from the guy claiming decanoate is faster acting than enanthate? LOL!
Exactly I say something based on how quick it affects the hormonal balance, sadly small minded people see the ester its attached to and think im talking about half lives and how long people think something kicks in based on A.R binding.
I didn't want to do this but hey... it will go over your heads.
Nandralone acts in a very unusual way to other steroids, it has pronounced neural affects which can cause depression anxiety and loss of libido very quickly because of its affects on affinity of the neurosteroids PS-3 and DHEAS at the sigma-1 site
Part of the reason for this is so to with steroid binding, deca can exert its affects by binding to other receptors, in this case the stigma-1 site and dhea site.
We all know what lowered DHEA can do, and how it affects us when its very low, Deca stops DHEA from working through binding to its target receptor.
This affects libido, in studies it takes less than 2 weeks to cause a very detrimental affect on neurosteroid receptors.
Dopamine receptors are another one it targets because it binds very quickly, and instead of being available, Nandrolone gets tied up with lots of hormonal changes in the system very quickly.
It has nothing to do with esters, but its affinity but you wont get that will you?
Expression of the dopamine D1-receptor transcript was elevated in the amygdala and decreased in the hippocampus while the transcript level of the dopamine D4-receptor was increased in the nucleus accumbens, This change especialy in the nucleus accumbens can cause a loss of pleasure, joy, stimulation and impulse, greatly affecting libido.
Simple solution is to prevent it doing these things, not by unbalancing your dopamine levels by taking Bromo or dostinex, and no need for arimidex with the doses your using, that will only lower estrogen which so you guys know doesn't do a great deal with deca bloat, deca acts itself as a progestin, run a deca only cycle and run a.dex, you will still get bloat, because its binding, unbind it and you wont need to worry.
Enjoy, that was for free x
Yawn.