caffeine

[Anybody]

what are the negative effects on BB of too much caffeine? Is it true that there are basically no side effects from 250mg/day or less?

 

[jenscats5]

HOW MUCH CAFFEINE IS "SAFE?"
MODERATION is the key. Most experts agree that 300 mg. of caffeine (about the amount contained in 3 cups of coffee) is a moderate intake. People who have certain health problems need to check with their doctor as they consider their caffeine intake. At this time, there is NO evidence that caffeine intake is associated with heart disease, hypertension, osteoporosis or high cholesterol. Because research is ongoing, recommendations about caffeine in the presence of these conditions seems conflicting. Talk with your doctor for guidance about your consumption. Some people are more sensitive to caffeine's effects than others and may feel effects at smaller doses. Pregnancy and aging may affect one's sensitivity to caffeine. There is no evidence that caffeine in beverage form is dehydrating. Its diuretic effects are usually compensated for by the beverage's fluid content. If you ingest caffeine from sports supplements (Clif Bar Ice series) or from prescription drugs or over-the-counter sources (No-Doz, etc.) be sure to drink adequate fluid to rehydrate yourself from caffeine's mild diuretic action.

http://www.mckinley.uiuc.edu/health-info/drug-alc/caffeine.html




Also: http://www.carbboom.com/education/caffeine.php

 

[psychedout]

Caffeine actually improves liver function, so enjoy your morning cup of cofee.

 

[psychedout]

Courtesy of the one and only, Jenetic.

Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States.

Ruhl CE, Everhart JE.

Social & Scientific Systems Inc., 8758 Georgia Avenue, Silver Spring, MD 20910, USA.

BACKGROUND & AIMS: Based on experimental and epidemiologic studies, we investigated whether coffee and caffeine consumption reduced the risk of elevated alanine aminotransferase (ALT) activity in persons at high risk for liver injury in a national, population-based study. METHODS: Participants were 5944 adults in the Third US National Health and Nutrition Examination Survey, 1988-1994, with excessive alcohol consumption, viral hepatitis, iron overload, overweight, or impaired glucose metabolism. Liver injury was indicated by abnormal serum ALT activity (>43 U/L). RESULTS: Elevated ALT activity was found in 8.7% of this high-risk population. In unadjusted analysis, lower ALT activity was associated with increasing consumption of coffee ( P = .001) and caffeine ( P = .001). Multivariate logistic regression analyses showed that the risk of elevated ALT activity declined with increasing intake of coffee ( P for trend = .034) and caffeine ( P < .001). Comparing persons who drank more than 2 cups per day with noncoffee drinkers, the odds ratio was .56 (95% confidence interval, .31-1.0). Comparing persons in the highest caffeine quintile with the lowest, the odds ratio was .31 (95% confidence interval, .16-.61). These relationships were consistent across subgroups at risk for liver injury and were relatively unchanged when analyses included the entire population or when limited to persons without impaired liver function or right upper quadrant pain. Fasting insulin concentrations did not mediate the effects. CONCLUSIONS: In this large, national, population-based study, among persons at high risk for liver injury, consumption of coffee and especially caffeine was associated with lower risk of elevated ALT activity.Gastroenterology. 2005 Jan;128(1):24-32.

Alanine Aminotransferase (ALT/SGPT)

ALT is a commonly used marker of hepatocyte injury. The enzyme appears in liver cells, with lesser amounts in the kidneys, heart, and skeletal muscles, and is a relatively specific indicator of acute liver cell damage. When such damage occurs, ALT is released from the liver cells into the bloodstream, often before jaundice appears, resulting in abnormally high serum levels that may not return to normal for days or weeks. The purpose of this blood serum test is to help detect and evaluate treatment of acute hepatic disease, especially hepatitis, and cirrhosis without jaundice.

Jenetic