I had gone on HRT for a short while after stopping some pro-hormones several years ago...all i knew was that i couldn't "get it up" and so went to the doctor. he checked my test and it was found to be low. i didn't mention to him that i had been taking the prohormones so until a few months later it had never occurred to me that it was the pro-hormones that had jacked me up. Anyway, he treated it with test cyp...150mg im every week with arimidex 1mg everyday. we checked my t and my e every other week and found that both numbers were in normal range. also, at that time i joined a hypogonadism bb on yahoo and found that arimidex is usually in the normal course of treatment with hrt. hope this helps.