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Granted, there's generally a huge markup in the price of supplements from the manufacturing/packaging costs to the end user. In an ideal world, we all wish a product that costs $5 to manufacture would sell for $10. Sorry it doesn't work that way fellas.
Supplement manufacturers generally sell to a distributor/wholesaler or retailer network at typical 40-50% discounts...so that product that costs $5 to make and retails for $30 is bringing the manufacturer a $10 profit per.
Factor in the cost of office and warehouse space, employees (bio chemists don't come cheap), r & d, operating expenses, and marketing (print, direct mail, internet), and you're looking at high 5 figure to low 7 figure overhead a month. If you think EVERYBODY in the supplement industry is laying back and counting their millions, think again.
In the case of 1ad, Pat Arnold is shooting straight. I see no reason why he has to defend the price of his product. The profit Ergopharm makes per bottle sold is probably less than the typical company makes per container of run of the mill whey protein sold.
I've priced raw 1ad from a Chinese supplier and it IS in the $3k/kilo range. That's why you don't see everybody putting out a 1ad product...the profit potential just isn't there currently.