I came across something interesting the other day......
1: Br J Nutr 1999 Dec;82(6):497-503 Related Articles, Books, LinkOut
Involvement of lipoic acid in plasma metabolites, hepatic oxygen consumption, and metabolic response to a beta-agonist in broiler chickens.
Hamano Y, Sugawara S, Kamota Y, Nagai E.
Department of Animal Science, Akita Prefectural College of Agriculture, Ohgata, Japan. [email protected]
The present study was conducted to determine the role of alpha-lipoic acid (LA) in plasma metabolites, hepatic O2 consumption, and beta-adrenergic response in broilers.
Note: Beta-adrenergic response.(Ephedrine is a beta-agonist)
In Expt 1, 12-d-old female broiler chicks were divided into three dietary groups and fed on diets with or without LA (5 or 50 mg/kg) until 4 or 6 weeks of age, as a 2 x 3 factorial arrangement.
(50mg/Kg is roughly 5000mg for a 100Kg BB'er. Exactly
what some people are consuming).
(For 80Kg it would be 4000mg, and for 90Kg 4500mg)
The dietary LA had no effect on growth rates (body weight, abdominal fat, breast muscle, and liver). The higher level of LA increased plasma non-esterified fatty acid and decreased plasma triacylglycerol concentrations only at 6 weeks of age. A 42% increase in hepatic respiration was observed in the 4-week-old chickens given 50 mg LA/kg diet. In Expt 2, 3-d-old female broiler chicks were treated with or without dietary LA at 50 mg/kg. At 30 and 31 d old, isoproterenol (2 mg/kg body weight per h) was continuously infused into a wing vein for 2 h, and changes in plasma glucose, triacylglycerol, and non-esterified fatty acid concentrations were analysed.
Note: Isopretenol is a beta-agonist.
Isoproterenol increased plasma glucose over basal levels maximally at 60 min.
Note: Without ALA.
Now, with ALA:
Furthermore, the glucose increase in the LA-treated chickens was 35% greater than that of the controls at this time.
(<Damn!> ALA+the beta agonist increased BG levels by
35%. This is indicative of EXTRA glucose being flooded
into the blood-stream by the "enhanced" beta-agonist).
Plasma non-esterified fatty acid and triacylglycerol concentrations were decreased by the isoproterenol infusion, regardless of LA administration. Therefore, the present study suggests that dietary LA has repartitioning effects on energy metabolism in
(Repartitioning effects: As we all already knew).
chickens (although this depends on age-related metabolic state)
(Interesting: Macro when you read this, it seems that ALA
would be cery beneficial for older people in terms of body
composition improvements).
and is a possible facilitator in the beta-adrenergic response of plasma glucose to a beta-agonist.
I swear I still have not been able to poke any holes in ALA's
amazing effects. It does literally EVERYTHING, and SAFELY
to boot. You can't get better than that.
Its the UNIVERSAL supplement if you ask me.
Fonz
1: Br J Nutr 1999 Dec;82(6):497-503 Related Articles, Books, LinkOut
Involvement of lipoic acid in plasma metabolites, hepatic oxygen consumption, and metabolic response to a beta-agonist in broiler chickens.
Hamano Y, Sugawara S, Kamota Y, Nagai E.
Department of Animal Science, Akita Prefectural College of Agriculture, Ohgata, Japan. [email protected]
The present study was conducted to determine the role of alpha-lipoic acid (LA) in plasma metabolites, hepatic O2 consumption, and beta-adrenergic response in broilers.
Note: Beta-adrenergic response.(Ephedrine is a beta-agonist)
In Expt 1, 12-d-old female broiler chicks were divided into three dietary groups and fed on diets with or without LA (5 or 50 mg/kg) until 4 or 6 weeks of age, as a 2 x 3 factorial arrangement.
(50mg/Kg is roughly 5000mg for a 100Kg BB'er. Exactly
what some people are consuming).
(For 80Kg it would be 4000mg, and for 90Kg 4500mg)
The dietary LA had no effect on growth rates (body weight, abdominal fat, breast muscle, and liver). The higher level of LA increased plasma non-esterified fatty acid and decreased plasma triacylglycerol concentrations only at 6 weeks of age. A 42% increase in hepatic respiration was observed in the 4-week-old chickens given 50 mg LA/kg diet. In Expt 2, 3-d-old female broiler chicks were treated with or without dietary LA at 50 mg/kg. At 30 and 31 d old, isoproterenol (2 mg/kg body weight per h) was continuously infused into a wing vein for 2 h, and changes in plasma glucose, triacylglycerol, and non-esterified fatty acid concentrations were analysed.
Note: Isopretenol is a beta-agonist.
Isoproterenol increased plasma glucose over basal levels maximally at 60 min.
Note: Without ALA.
Now, with ALA:
Furthermore, the glucose increase in the LA-treated chickens was 35% greater than that of the controls at this time.
(<Damn!> ALA+the beta agonist increased BG levels by
35%. This is indicative of EXTRA glucose being flooded
into the blood-stream by the "enhanced" beta-agonist).
Plasma non-esterified fatty acid and triacylglycerol concentrations were decreased by the isoproterenol infusion, regardless of LA administration. Therefore, the present study suggests that dietary LA has repartitioning effects on energy metabolism in
(Repartitioning effects: As we all already knew).
chickens (although this depends on age-related metabolic state)
(Interesting: Macro when you read this, it seems that ALA
would be cery beneficial for older people in terms of body
composition improvements).
and is a possible facilitator in the beta-adrenergic response of plasma glucose to a beta-agonist.
I swear I still have not been able to poke any holes in ALA's
amazing effects. It does literally EVERYTHING, and SAFELY
to boot. You can't get better than that.
Its the UNIVERSAL supplement if you ask me.
Fonz