1,4-androstadienedione is a precursor to boldenone, and is also the most orally active prohormone available.
5-alpha androstanediol is a precursor to dihydrotestosterone. I hope you are looking at 5-alpha-androstane-3-alpha,17-beta-diol, which coverts to DHT 4.5 times better than the old 3-beta isomer according to in-vivo serum recovery studies.
First, we know it converts to 17beta (boldenone) with great efficacy and stability. There is no need to look for another enzyme pathway. While the diol of the andro offers an advantage over the dione, I see none with the 1,4, and in fact expect conversion to be a little lower.
Also, as Pat Arnold pointed out, the diol has an A ring that is structurally similar to estradiol. It will possibly bind the ER and exert estrogenic activity. No studies, but looks intriguing on paper.
I've been offered the diol from manufacturers and importers several times, and do not want to work with it. If I did, it would be simply to profit off of the superior rep androstenediol has built up (vs adione), which would be dishonest when I believe strongly the dione is better.
Thanks, got just one more question. What is the most effective amount of 1,4-ad to take at a bodyweight of 250, and should it be stacked with anything else.
The recommended dose is 3-6 caps daily. I will say first that I get a lot of extremely good feedback from people taking as little as 4 a day. I have yet to hear someone call in with a complaint of no gains at this dosage level. Actually I have had no complaints of this nature at all yet, which is a little wierd for any supplement co.
That said, I think it works best between 6 and 9 caps daily. Could it be stacked? Most certainly. But I'm hesitant to recommend with what, as it is like saying if you have dbol you should stack it with deca. You can, but you can stack it with a bunch of other compounds depending on what you are looking for..
Most commonly I hear Boldione + 3-alpha (our DHT precursor) or Boldione + 1-AD for more definition and strength gains, or Boldione and heavy Andro use with maybe Avant Lab's or Ergo's dermal products for more mass.