Why would Ligandrol and mk677 cause reduced bone mineral content?

[FutureGem]

I'm considering a SARMs cycle. However, I don't want to get osteoporosis. This study says Ligandrol and mk778 can reduce bone mineral content: https://pubmed.ncbi.nlm.nih.gov/36303408

Is not case, what exactly caused the problem? Is reduction in bone mineral content inherently caused by Ligandrol, or was it caused due to testosterone suppression, which led to less aromatization, less estrogen, and altered calcium absorption? If I use enclomiphene or clomiphene during a cycle with Ligandrol, will I still get reduced bone mineral content?

 

[MUSTANG_18]

I'm considering a SARMs cycle. However, I don't want to get osteoporosis. This study says Ligandrol and mk778 can reduce bone mineral content: https://pubmed.ncbi.nlm.nih.gov/36303408

Is not case, what exactly caused the problem? Is reduction in bone mineral content inherently caused by Ligandrol, or was it caused due to testosterone suppression, which led to less aromatization, less estrogen, and altered calcium absorption? If I use enclomiphene or clomiphene during a cycle with Ligandrol, will I still get reduced bone mineral content?

@FutureGem you sound like another guy from EVO I saw
you that european guy that wont log?

 

[Noah Wixx]

@FutureGem you sound like another guy from EVO I saw
you that european guy that wont log?

Definitely him I'm convinced now

 

[stevesmi]

you can pull up a study on any PED that will show bad things happening

anyone who thinks otherwise is a fool. this is a risk we take by using these products

 

[Monstro]

Monstro says you sound familiar lol

 

[Vadim Fedorov]

if you are worried then don't use it that simple

 

[2Thick]

I doubt if you run it eight or twelve weeks you'll have any such issues happening

 

[e2]

did the people in the study run it for a long. Of time and at what dosage

 

[StevenDarwinMD]

This thread/post was reviewed by our Medical Review board.

 

[Ulter]

I can also argue that any steroid can cause a stroke

 

[chesty]

anabolic steroids can cause blood clots to increase that's a fact as well

 

[ROIDDERS]

anything you take can cause issues if you abuse especially

 

[ceo]

Bros we still waiting for your log let's see it

 

[25homes]

if you scared dont take it real simple

 

[FutureGem]

you can pull up a study on any PED that will show bad things happening

anyone who thinks otherwise is a fool. this is a risk we take by using these products

Correct, but some side effects are very scary and dangerous.

Reduced bone mineral content can lead to osteoporosis, which is brutal.

As for Ligandrol, I have a hypothesis.

Ligandrol is suppressive to testosterone production. Suppressed testosterone means less aromatization and estrogen, which negatively impacts calcium absorption and bone metabolism. Estrogen is needed for calcium absorption.

So, if you run Ligandrol without a synthetic testosterone base, you will get reduced testosterone and estrogen.

So, if they ran solo Ligandrol in the study, that's what may caused the reduced bone mineral content.

And I want to know what I need to use in addition to Ligandrol. Since Ligandrol doesn't add exogenous androgens/testosterone to the body, this means testosterone production will be suppressed, but not entirely shut down like it happens when steroids (exogenous androgens) are used. If it's about just a suppression, not a complete shut down, can using clomiphene or enclomiphene keep my testosterone levels within normal range during a Ligandrol cycle, or do I have to inject exogenous testosterone at a TRT dose?

I don't want exogenous testosterone for now. I prefer to use a method that will keep my natural T production ongoing without having to replace it with exogenous hormones.

 

[FutureGem]

did the people in the study run it for a long. Of time and at what dosage

It's unknown for how long they run it. All the information about the study can be found in the link in my original post, and it doesn't show time.

 

[FutureGem]

anything you take can cause issues if you abuse especially

If used at recommended doses like 10 or 20 mg a day, can such problems happen?

 

[ballin2504]

Definitely him I'm convinced now

Dude it’s him he started with a mad face then changed his pic to a pic of Andrew Tate and now a new name with a pic of Andrew Tate. lol

 

[Noah Wixx]

Dude it’s him he started with a mad face then changed his pic to a pic of Andrew Tate and now a new name with a pic of Andrew Tate. lol

Yup 100% him brother

 

[dylangemelli]

SMFH, now that is where we get to crazy status... we have seen this before in the past and it leads to nothing good..

 

[FutureGem]

SMFH, now that is where we get to crazy status... we have seen this before in the past and it leads to nothing good..

You mean the doses I'm considering?

 

[dylangemelli]

You mean the doses I'm considering?

LMFAOOOO

 

[FutureGem]

LMFAOOOO

What?

 

[the_alcatraz]

What?

many dont believe you now after your stint at EVO

 

[SteveMobsterG]

Look again at any study . Training and diet will improve bone and mineral content

 

[FutureGem]

Look again at any study . Training and diet will improve bone and mineral content

Yes, correct. A diet that has enough calcium can help. But the same diet won't have any effects if bone metabolism and calcium absorption are negatively impacted.

 

[FutureGem]

many dont believe you now after your stint at EVO

What are you talking about? I don't have an account on Evo.

 

[dylangemelli]

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">via GIPHY</a></p>

 

[FutureGem]

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?

 

[MUSTANG_18]

Yes, correct. A diet that has enough calcium can help. But the same diet won't have any effects if bone metabolism and calcium absorption are negatively impacted.

@FutureGem thats try but if you use mk677 at your age what would be your benefit no need

What are you talking about? I don't have an account on Evo.

i think you do have an account on evo bro