So first hand knowledge on this subject.  Afeedz may have it correct.... would like some honest opinions.
I have been on HRT for a little over 1 yr.  Started out 100 / week.  I think I metabolize it really quickly.  Could feel it instantly in my moods.  Called shot day my love everyone day. Things leveled off and Doc bumped me to 120/EW. Then things started getting a little weird.  Shot day turned into ass chewing day around the office and I am not an ass chewing type.  Used to lose my temper when younger but not really a confrontation person.  
This happened really bad on 4 different occasions and they were both at the end of my vial.  Nothing being imagined here.  I remember the second time this happened, I was sitting in my office just pissed off at everyone and thought.. fuck it is shot day again.  I have sense cut my self back to 100/week and remember to shake the shit out of my vial every time I use it.
Anyone else experience something towards the end of their dose?  I do remember on the first Vial I had, I got like an allergy on the last two injections.  Felt almost like I was coming down with a cold for about 4 hrs then it would go away.
Before all you fucks start talking about cheap gear etc, this is Dr prescribe big pharm stuff.
ok. thoughts?