Posted by Unique on March 08, 1997 at 16:48:41:
In Reply to: Re: ANDROSTENEDIOL REVISITED posted by PA on March 07, 1997 at 13:23:04:
: : QUESTION FOR THE PRO'S (UNIQUE,HULKSTER, ANIMAL ETC)
: : I saw the previous postings about conveting DHEA to
: : methandriol to methyltest. Did the recipe ever get
: : posted??? Inquring muscles want to know... Has anyone
: : had any success with the conversions?
:
: Maybe I have at one time. Methyl grignard reaction followed by hydrolysis and get rid
: of the excess unreacted ketone with semicarbazide HCl. Then oppenauer oxidation
: with Aluminium isopropoxide in toluene with cyclohexanone at reflux to get methyltest.
: Workup of the oppenauer reaction is not easy though.
:
: PA
:
: if so where can
: : I get the post(recipe) Also, Would it be better to
: : prepare a DMSO solution of ANDOSTENE 50 instead of
: : ingesting it?
An alternative reaction would be to take DHEA, treat it
with trimethylsulphonium iodide, separate out the tetrhydropyranyl ether
via thin layer chromatography and reduce the latter via lithium
aluminum hydride to methandriol--which can be oxidized via oppenauer to
17-meth. Of course, Pat's way of treating the DHEA with methylmagnesium
bromide is a little easier.
Keep up the fight
Unique