receptor downregulation

Steroid Receptors Let's start at the top. How steroids are able to give us the desired effects is, in fact, via two methods of action. According to NIH.Gov: Steroids can act through two basic mechanisms: genomic and non-genomic. The classical genomic action is mediated by specific intracellular...

Also called HCG-induced LH-receptor down regulation as a result of using too much HCG or for too long. Should it happen, will it stay forever, or will finally go away in weeks/months/years? I have heard some speak of there being 2 types of Leydig cell desensitization, one that is temporary and...