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How many of you use/used insulin & why?
- Thread starter GUARDIAN
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I only know one person personally that has used it for any length of time. Well trained, and lean guy, i actually asked him about it the other day he said he wouldnt do it again. The timing of basically EVERYTHING you eat he said was the biggest factor that stopped him from wanting to do it again. He also said he saw minimal results and was on quite a bit of other stuff at the time... I believe Var, Tren Ace, Prop...
It takes a lot of work to use it to good effect but it seems like it HAS to make an impact... And I am under the impression that used properly it should have no impact on long term insulin resistance...?
It takes a lot of work to use it to good effect but it seems like it HAS to make an impact... And I am under the impression that used properly it should have no impact on long term insulin resistance...?
The underlying causes of insulin-resistant states can be categorized as follows:
Prereceptor
Abnormal insulin (mutations)
Anti-insulin antibodies
Receptor
Decreased number of receptors (mainly, failure to activate tyrosine kinase)
Reduced binding of insulin
Insulin receptor mutations
Insulin receptor–blocking antibodies
Postreceptor
Defective signal transduction
Mutations of GLUT4 (In theory, these mutations could cause insulin resistance, but polymorphisms in the GLUT4 gene are rare.)
Combinations of defects are common. Obesity is associated mainly with postreceptor abnormality and is also associated with a decreased number of insulin receptors.
Obesity is the most common cause of insulin resistance.
Source: Samuel T Olatunbosun, MD, Physician, Internal Medicine
Prereceptor
Abnormal insulin (mutations)
Anti-insulin antibodies
Receptor
Decreased number of receptors (mainly, failure to activate tyrosine kinase)
Reduced binding of insulin
Insulin receptor mutations
Insulin receptor–blocking antibodies
Postreceptor
Defective signal transduction
Mutations of GLUT4 (In theory, these mutations could cause insulin resistance, but polymorphisms in the GLUT4 gene are rare.)
Combinations of defects are common. Obesity is associated mainly with postreceptor abnormality and is also associated with a decreased number of insulin receptors.
Obesity is the most common cause of insulin resistance.
Source: Samuel T Olatunbosun, MD, Physician, Internal Medicine
Mavafanculo
New member
I'll say the same thing here I said in re DNP.
Why would someone who isnt competing at an advanced level with big bucks in prizes and sponsorships on the line risk one dose death?
The audience at EF is primarily beginner and intermediate level BB'ers. Top pro's arent coming here for advice on how to use insulin, young BB'ers are. AND WE AS A SITE SHOULD DO EVERYTHING WE CAN TO DISCOURAGE ITS USE IN THAT DEMO.
When you're close to maxing on juice assisted gains and then juice + GH, and you're a hi-stakes competitor, then think about insulin.
For most, consider that its more likely to get you fat dead or diabetic than diesel.
If your calculations are off a bit, or you forget to bring along your sugar fix you could end up in a coma, maybe with brain damage, maybe dead.
Or if they're off in the other direction you end up looking Pig-like.
Imagine, some of the sites advise wearing a Medic-Alert Bracelet in case you go unconscious and someone finds you.
FOR WHAT?
p.s. my guess on the mechanism for long-term problems would be downregulation of insulin receptors to try to deal with the insulin flood (or reduced signal transduction). Then when you remove the extra insulin, psysiological endogenous amounts results in the equivilent of insulin resistence and the pancreas needs to pump out higher and higher amounts to adeqautely clear glucose from the blood. after a while the pancreas give out. same process as type II diabetes, except self-induced.
Just not worth the risks for 99% of the EF bodybuilding community
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Why would someone who isnt competing at an advanced level with big bucks in prizes and sponsorships on the line risk one dose death?
The audience at EF is primarily beginner and intermediate level BB'ers. Top pro's arent coming here for advice on how to use insulin, young BB'ers are. AND WE AS A SITE SHOULD DO EVERYTHING WE CAN TO DISCOURAGE ITS USE IN THAT DEMO.
When you're close to maxing on juice assisted gains and then juice + GH, and you're a hi-stakes competitor, then think about insulin.
For most, consider that its more likely to get you fat dead or diabetic than diesel.
If your calculations are off a bit, or you forget to bring along your sugar fix you could end up in a coma, maybe with brain damage, maybe dead.
Or if they're off in the other direction you end up looking Pig-like.
Imagine, some of the sites advise wearing a Medic-Alert Bracelet in case you go unconscious and someone finds you.
FOR WHAT?
p.s. my guess on the mechanism for long-term problems would be downregulation of insulin receptors to try to deal with the insulin flood (or reduced signal transduction). Then when you remove the extra insulin, psysiological endogenous amounts results in the equivilent of insulin resistence and the pancreas needs to pump out higher and higher amounts to adeqautely clear glucose from the blood. after a while the pancreas give out. same process as type II diabetes, except self-induced.
Just not worth the risks for 99% of the EF bodybuilding community
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Mavafanculo said:
That is some scary shit Mav. Good post though. It'll keep the noobs from pumpin insulin like it's B12.
Mavafanculo
New member
8and20 said:Good points as always hence my questions and curiosity to those to do use it.
now u have scared away all my research subjects that do use it from posting
Mission Accomplished lol.
lets go talk about tren instead
smoke67
New member
I have said it before and I will say it again. I see no point in trying something that can go very wrong if you do not know what you are doing. In my profession, I see what insulin and bad timing on eating can do at least three times a week. I have known guys that do it along with GH but not me!!!
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