Gestrinone... The first progesterone-reducing med for Tren/Deca users?

Gestrinone


How does it work?

Gestrinone is a synthetic hormone which acts on a part of the brain called the pituitary gland. The pituitary gland controls the levels of different types of sex hormones (oestrogen and progestogen) produced by the body. The production of the hormones is responsible for menstruation and ovulation in women. By acting on the pituitary, gestrinone decreases the production and release of these sex hormones. Gestrinone is used to treat a condition called endometriosis, in which the tissue (endometrium) normally lining the womb grows on different organs outside the womb. The growth of this endometriotic tissue is under the influence of sex hormones. Decreasing the production of these sex hormones removes the stimulation for growth of the endometriosis. Gestrinone is also thought to act directly on the endometrial tissues to prevent their growth.

Medications

The basic approach in hormonal treatments for endometriosis is to block production of female hormones (estrogen and progesterone) or to prevent ovulation with other hormonal effects. Hormonal agents are used for pain relief only. None improve fertility rates and in some cases may delay conception. Specific hormonal agents may have different effects for women with endometriosis.

* Inducing Pseudopregnancy: Agents that. Oral contraceptives that contain estrogen and progestins mimic a pregnant state and block ovulation. (Progestins are natural or synthetic forms of progesterone). Progestins may also be used alone, since they have specific effects that can cause the endometrial tissue itself to atrophy.
* Inducing Pseudomenopause: Gonadotropin-releasing hormone (GnRH) agonists or gestrinone, an anti-progesterone that mimic menopause. They reduce estrogen and progesterone to their lowest level.
* Inducing On-going Blockage of Ovulation. Danazol, a derivative of male hormones, is a powerful ovulation blocker.

Going to have to say no bro. This med states is blocks production and release from the endocrine gland( pituitary in this case) itself. Does nothing for progesterone introduced through artificial means such as ours. Now, if it prevented progesterone from binding, or prevented the drugs from aromatizing INTO progesterone, that would be different, but this appears only to block natural production, which won't help us. Nice read though.

Yeah blocking the producting of the endocrine system is not what we need.

Anyone else?

^^

Based on what that says it won't do you any good if the Progestin has been injected already.

^

jenetic maybe?