posted February 22, 2000 02:46 AM         

Clinical trials were run and patents were applied in the US and Europe (late '70s) for its (7-isopropoxyisoflavone)use as "an anabolically effective compound for use as a pharmaceutical or a feed additive." The necessary research results were convincing enough, and the patents were granted.
So what did the trials reveal about Methoxy-7 that warranted the granting of a patent? In the standard rat levator ani test, used with anabolic steroids to determine their anabolic:androgenic ratio, it was determined that Methoxy-7 was, indeed, highly anabolic, yet totally free of any androgenic or estrogenic effects.
ALL GAINS CONSISTED MAINLY OF LEAN TISSUE and were accompanied by an increase in vitality. After detailed investigation, no alteration of endocrine function was found, clearly indicating that GAINS WERE NONHORMONAL IN ORIGIN.
These compounds demonstrated INCREASED AND FASTER PROTEIN UTILIZATION, via labeled albumin. When used with human patients suffering from pathological wasting, and after only a few weeks of use, an average gain of two to three kilograms was noted.
Another characteristic feature of the anabolic effect was an increase in calcium, phosphorous, potassium, and nitrogen retention, to a significant degree. In other experiments, the CATABOLIC EFFECTS OF CORTISONE WERE PARTIALLY SUPPRESSED, and it was concluded that "identical doses of anabolic steroids do not exert anabolic effects stronger than those of these compounds!"
Chinoin pointed out in their trials the important advantage of Methoxy-7 over anabolic agents belonging to the sterane group (steroids) in that it DOESN'T EXHIBIT ANDROGENIC OR LIVER-DAMAGING EFFECTS. It also decreases oxygen consumption of tissues and LOWERS CHOLESTEROL.
Ironically, the only thing that Chinoin can't determine is how these compounds work.

Although we are in the early days of Methoxy-7, this compound seems very exciting. We're looking at a highly anabolic agent that's non-hormonal and, therefore, doesn't interfere with normal endocrine function-ideal for both clean athletes and the chemically assisted, as there's no feedback inhibition of endogenous hormones.
No, I'm not going to make the decidedly unwise assertion that the effects of Methoxy-7 are identical to that of anabolic steroids. But it looks, at least, as if we're in the same ballpark.