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  Why bother stacking?

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Author Topic:   Why bother stacking?
latona

Amateur Bodybuilder

Posts: 173
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Registered: Nov 2000

posted December 21, 2000 04:00 PM

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Could someone explain this to me: If there is only type of androgenic receptor and all AAS are fighting for the same receptors, what is the advantage of stacking many different drugs together? I know there's got to be one because so many people swear by it.

------------------
Anima Sana In Corpore Sano


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WILDTHINGURI

Pro Bodybuilder

Posts: 370
From:MA
Registered: Feb 2000

posted December 21, 2000 04:05 PM

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WELL BRO ITS LIKE THIS DRINKING MILK IS GOOD ALONE BUT PUT CHOCLATE IN IT AND YOU HAVE CHOCLATE MILK TASTE EVEN BETTER..

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" SOMETIMES THE MOST OBVIOUS IS THE UNOBVIOUS"



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Scooter

Amateur Bodybuilder

Posts: 73
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Registered: Sep 2000

posted December 21, 2000 05:57 PM

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Some compounds work through AR binding, some work through non AR binding pathways.

To the best of my knowledge (mostly from lurking on this board) the only compounds which work through BOTH AR binding and non AR binding pathways are Test and Trenbelone.

If you are using any other compound, you should stack.

For intance suppose you are going for mass and are using DECA. DECA exhibits strong AR binding. DBOL is a good compliment because it acts through non AR binding pathways.

Another example might be if you are using Primo. Primo binds to AR receptors strongly. Winny is a good compliment to Primo as it acts through non AR bining mechanisms.

This is why DECA/DBOL and PRIMO/Winny pairs are often said to be "made for each other"

Now should you stack on top of Test or Tren...that is another question.


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macavoy

Amateur Bodybuilder

Posts: 125
From:
Registered: Feb 2000

posted December 21, 2000 07:15 PM

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However many say on your first few cycles one drug alone is enough. Learn how your bod responds with each drug seperately before you add more.


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latona

Amateur Bodybuilder

Posts: 173
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Registered: Nov 2000

posted December 21, 2000 09:44 PM

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thanks Scooter. that helps clear things up. How would primo and eq be together?

------------------
Anima Sana In Corpore Sano


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Eramthgin

Elite Bodybuilder

Posts: 611
From:Richmond, Texas USA
Registered: Jun 2000

posted December 21, 2000 09:45 PM

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Now take the Milk the choclate and add some ice cream.

------------------
Don't put off to tomorrow what you can do today.

If you enjoy it today you can always do it again tomorrow.


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Anabolicum Mister

Elite Bodybuilder

Posts: 845
From:Canada
Registered: Mar 2000

posted December 21, 2000 10:41 PM

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Not only AR binding, but also serum protein binding. In that way, more of one steroid in the stack will be free as the other steroid occupies the binding protein receptor.


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lpw

Amateur Bodybuilder

Posts: 109
From:MA
Registered: Jul 2000

posted December 22, 2000 01:17 AM

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good question. I'd like the skinny on a primo + eq. stack, too.


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Scooter

Amateur Bodybuilder

Posts: 73
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Registered: Sep 2000

posted December 23, 2000 12:45 AM

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Good question guys, with regards to EQ. I have actually heard some conflicting info here. Hope fully some VETS/ BIOCHEM wizzes can help!

Everyone says that EQ (Boldenone) has similar (strong) AR binding to Nandrolone (Deca)

However, as noted on E2's recent quiz, EQ is VERY similar to DBOL. The base molecule is alsmost exactly the same. In DBOL, it is 17aa while in EQ the molecule is attached to a fatty acid chain.

So what is the deal....it seems that DBOL and EQ would act through similar mechanisms...yet it is often noted that DBOL works through non AR pathways and EQ exhibits strong AR binding.

If the "packaging" (17aa Dbol vs fatty acid bound EQ) does effect the mechanism, and EQ does bind strongly to AR's, it might not give the best synergy when stacked with Primobolan.

Primo/Winny or EQ/Winny would be better.


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Narcissist

Amateur Bodybuilder

Posts: 60
From:Hazelwood,MO,63042
Registered: Dec 2000

posted December 23, 2000 01:38 AM

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Stacking...HMMMM,well can we say..."SYNERGY"? ...ah, yes to some may be too big of a word, get a dictionary.


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yiyangzhi

Amateur Bodybuilder

Posts: 64
From:Singapore
Registered: Dec 2000

posted December 23, 2000 01:40 AM

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then a deca & primo combo is not optimal, 'cos both compete for the same ARs?


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skin88

Amateur Bodybuilder

Posts: 61
From:
Registered: Jul 2000

posted December 23, 2000 02:03 AM

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Scooter, I would like to know a few things then. Test goes through AR pathways and dbol doesn't, I'm going to be taking a gram of test cyp with 500mg EQ and 35mg dbol daily, and since the eq binds strongly through the AR, does that mean it might lower the effect of juice or not really work well with test? Also, at 1g of test cyp, am i likely to be saturating my receptors from that only? Let me know if you think the cyp/dbol/eq stack is a good choice. thanks.


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yiyangzhi

Amateur Bodybuilder

Posts: 64
From:Singapore
Registered: Dec 2000

posted December 23, 2000 06:51 AM

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bump for this post.


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latona

Amateur Bodybuilder

Posts: 173
From:
Registered: Nov 2000

posted December 23, 2000 09:37 AM

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Narcissist... your handle could not be more appropriate.

'Synergy' ... that's you're whole answer? Synergy simply means 'to work together'. It is derived from the new latin synergia and the greek synergos (not sure about the greek, but I'll have to check). To say stacking works because of synergy is like saying that steroids work well together because they work well together. Very helpful, indeed. This must be a new word for you, since you seem very eager to try it out. I noticed you posted the same nonsense on at least two different threads in the past day.

I've got a word for you: deficate. That's what I'm going to do on your head if you post this type of arrogant, unhelpful flame on my threads again.

------------------
Anima Sana In Corpore Sano


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yiyangzhi

Amateur Bodybuilder

Posts: 64
From:Singapore
Registered: Dec 2000

posted December 23, 2000 09:43 AM

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Narcissist, or how abt Asspisshit?


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sxjunky

Cool Novice

Posts: 36
From:red light district
Registered: Dec 2000

posted December 23, 2000 10:49 AM

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LOL, Narcissist loves to use the word "synergy", I saw him throw that term around on another post.


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Donald Smoot

Amateur Bodybuilder

Posts: 207
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Registered: Aug 2000

posted December 23, 2000 03:43 PM

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I think part of the answer is the desire to do more while not buying Arimedix. Say you are doing 800mg./wk of test. Now the conversion of test into estrogen at that dose causes a tolerable amount of bloating. If you want to do more, you will bloat to much. So you must then buy expensive Arimedix to reduce estrogen, or stack the 800 mg. test with something like Deca that won't convert. I think if Arimedex was cheap Deca wouldn't sell as well as it does.


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Narcissist

Amateur Bodybuilder

Posts: 60
From:Hazelwood,MO,63042
Registered: Dec 2000

posted December 23, 2000 03:47 PM

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latona, hows your mom feeling?


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skin88

Amateur Bodybuilder

Posts: 61
From:
Registered: Jul 2000

posted December 23, 2000 05:05 PM

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bump for scooter


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thesuperstar

Amateur Bodybuilder

Posts: 295
From:FLORIDA
Registered: Jan 2000

posted December 23, 2000 07:33 PM

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milk and chocolate?

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http://thesuperstar.pathbot.com
UPDATED18DEC00


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Scooter

Amateur Bodybuilder

Posts: 73
From:
Registered: Sep 2000

posted December 24, 2000 06:32 PM

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skin88,

First things first...I am really not that knowledgeable...and when I don't know I try to keep my mouth shut and wait for a VET to offer a point of view.

The stacking question was pretty easy to answer so I did.

As I said in my second post I personally am confused about EQ and DBOL...since they are chemically very similar (it was the one question on E2's quiz which I knew and felt that most people would miss!), but everyone says they work so much differently. I hope a VET can offer some guidance here. (See my pervious post above?)

I would think that TEST, DBOL, EQ would be a very balanced stack (assuming EQ and DBOL work the way everyone says they do) Test as the base, and DBOL (fast action early in cycle) EQ (low aromitization till end of cycle) to compliment it.

As far as AR down regulation, saturation points, serum protein binding, etc...you are beyond me...I wish I could answer.... perhaps Anabolicum Mister could help????


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