Anadrol 50 is unfortunately also the most harmful oral steroid. Its intake can cause many considerable side effects. Since it is I 7-alpha alkylated it is very liver-toxic. Most users can expect certain patho-logical changes in their liver values after approximately one week. An increase in liver values of both the enzymes GOT and GPT also called transaminases, often cannot be avoided. Elevated GOT and GPT values are indications of hepatitis, i.e. a liver infection. Those who discontinue oxymetholone will usually show normal values within two months. Longer intake and/or higher doses can cause a yellow discoloration of fingernails, eyes, or skin 0aundice). This is because oxymetholone induces an increase of biliburin in the liver, producing a bile pigment which causes the yellow discoloring of the skin. The liver enzyme gamma-GT also reacts sensitively to the oxymetholone, causing it to elevate. If high dosages of Anadrol 50 are taken over a long period, there is an increased risk that the de-scribed liver changes could end up damaging the liver. During the intake of Anadrol 50, the liver values, GOT, GPT, bilirubin, gamma--GT and alkaline phosphatase (AP), as well as the LDH/HBDH quo-tient, should always be checked by a competent physician. Anadrol 50 (representing all oxymetholone-containing steroid products) is the only anabolic/androgenic steroid which was linked with liver cancer.

The compound oxymetholone easily converts into estrogen. This causes signs of feminization (e.g. gynecomastia) and the already -mentioned water retention which in turn requires the intake of antiestrogens (e.g. Nolvadex and Proviron) and an increased use of diuretics (e.g. Lasix) before a competition. The increased water re-tention, in addition to the aesthetical problems, can be further detri-mental since it may cause high blood pressure. In extreme cases the intake of an anti-hypertensive drug, e.g. Catapresan, may be neces-sary. Since a substantial amount of the compound converts into dihydrotestosterone (DHT) in the body, it is possible that, with a given disposition, severe acne and an increased hair loss can occur. Bodybuilders who experience severe steroid acne caused by Anadrol can get this problem under control by using the prescription drug Accutane.

Other possible side effects may include headaches, nausea, vomit-ing, stomach aches, lack of appetite, insomnia, and diarrhea. The athlete can expect a feeling of "general indisposition" with the in-take of Anadrol which is completely in contrast to Dianabol which conveys a "sense of well-being". The increased aggres-siveness is caused by the resulting high level of androgen and occurs mostly when large quantities of testosterone are "shot" simulta-neously with the Anadrol. The body's own production of testoster-one is considerably reduced since Anadrol has an inhibiting effect on the hypothalamus, which in turn completely reduces or stops the release of GnRH (gonadotropin releasing hormone). For this reason the intake of testosterone-stimulating compounds such as HCG and Clomid is absolutely necessary to main-tain the hormone production in the testes.

Anadrol 50 is not recommended for women since it causes many and, in part, irreversible virilizing symptoms such as acne, clitorial hypertrophy, deep voice, increased hair growth on the legs, beard growth, missed periods, increased libido, and hair loss. Anadrol is simply too strong for the female organism and accordingly, it is poorly tolerated.

-L101

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