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Author | Topic: It's not about mg!!! And yes I'm pissed!!! | ||
Cool Novice ![]() ![]() Posts: 47 |
All of you only talk about mg, ml, underdosed,... You should finally realize that the formulation (galenic) of a product is way more important than the content of active ingredient. Never heard of BIOEQUIVALENCE and BIOAVAILABILITY STUDY!!!! Apperently not, otherwise you wouldn't buy many of the veterinary products and than complain they don't work so good!
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Amateur Bodybuilder ![]() ![]() Posts: 195 |
Who's saying veterinary products don't work? ![]() ![]() ![]() ![]() | ||
Cool Novice ![]() ![]() Posts: 47 |
Never said that veterinary product don't work, just that several of them have a low bioequivalence. There are also a few human products with a low bioequivalence. My point is that 200mg Ttokkyo nandrolone are not as effective as 200mg Deca-Durabolin (and this is just an example). Guys should start to realize this. The galenic of a drug is extremely important and should be considered when you choose to buy a product. ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 195 |
What proof do have that 200mg of "ttokkyo" nandrolone is not as effective as 200mg of deca-durabolin? Everyone who uses the ttokkyo nan300 seems to think it works quite well. ![]() ![]() ![]() ![]() | ||
Elite Bodybuilder ![]() ![]() ![]() Posts: 683 |
Why are you "PISSED!" ?? vet products and ttokkyo's products are cheaper. so why does it bother you if I choose to use a cheaper product? I appreciate the info though. ------------------ quote: ![]() ![]() ![]() ![]() | ||
Elite Bodybuilder ![]() ![]() ![]() Posts: 830 |
I don't understand. 200mg of the drug nandrolone decanoate should have the same bioavailability, whether veterinary or human grade. I'm not talking about what it says on the label, but the actual amount of drug. If I'm wrong, please enlighten me as to why. [This message has been edited by Anabolicum Mister (edited December 09, 2000).] ![]() ![]() ![]() ![]() | ||
Moderator ![]() ![]() ![]() ![]() Posts: 5635 |
Well i'm wondering if he's talking about isomers or stereoisomers is what he's talking about. Although i don't know if that would work at all, i don't know if a stereoisomer would even activate the AR in any way. For those who don't know, a steroisomer has the same chemical make up yet a different orientation in space. I don't know if 'lower quality' products are full of steroisomers or not. Perhaps they are, and perhaps they don't activate the AR, that could be why we see different results on the same amount of drug from different companies.
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Elite Bodybuilder ![]() ![]() ![]() Posts: 754 |
yo italy.... if you know info that others don't, please don't get pissed....share it joyously and let others revel in your vast pool of knowledge....when you say you're "pissed", it makes you look like a bitter mother fucker.....don't you agree? PA >|===|--- PS....i'm thinking along the same lines of E2....do anabolics typically have racemic mixtures of stereoisomers? i'd like to know, bro [This message has been edited by Pharm Animal (edited December 09, 2000).] ![]() ![]() ![]() ![]() | ||
Elite Bodybuilder ![]() ![]() ![]() Posts: 830 |
Exactly P.A. I've heard of racemic mixtures of substances like clen, but never of anabolic steroids. As far as I know, there are no stereoisomers of anabolic steriods. If a steroid has a different geometry it is usually given a different name. At least in terms of side groups. Maybe there are isomers of the cyclopentaphenanthrene ring? [This message has been edited by Anabolicum Mister (edited December 10, 2000).] ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 147 |
Sorry,I don't understand italian.Can you,please,stop being pissed off,and get more specific about "galenic",also BIOEQUIVALENCO and BIOAVAILABILITO? ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 135 |
Bump. Come on Italy tell us more. ![]() ![]() ![]() ![]() | ||
Moderator ![]() ![]() ![]() ![]() Posts: 1319 |
BUMP i am interested to hear this as well ------------------ ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 66 |
Seriously, I think you guys flew over his head. B-) ![]() ![]() ![]() ![]() | ||
Pro Bodybuilder ![]() ![]() ![]() Posts: 445 |
I was thinking about the same subject the other day E2, after all this recent talk about vet underdosing and such. Bump for clarification by ITALY... ------------------ ![]() ![]() ![]() ![]() | ||
Cool Novice ![]() ![]() Posts: 47 |
Sorry I couldn't reply sooner, I was out for the week-end. First I would like to apologise: to say that I am pissed was exagerated, it wasn't my best day! About BIOEQUIVALENCE and BIOAVAILABILITY: The way a drug is made (galenic formulation) influences the bioequivalence. Let me make a clear example: You see, making Viagra (by Pfizer) is not so easy, it's not enough to have the active ingredient and simply press it into a tablet! I'm sure that many manufacturers of fakes have been frustrated by this. That is also one of the meaning of the "Exp. Date": to tell that the bioequivalence of a product is guaranteed untill that date. Other example: paper-steroids offer a greater surface to the air (more contact to oxygen) than blistered tablets. This will cause a faster decrease of bioequivalence with time. To talk simple: Knowing the bioequivalence of products will help you save money and get more results from less ml/mg. Now I'm tired, it's 2:30am here. Good night everybody, hope you make nice dreams. ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 171 |
Elite friends, Could this be the reason some powdered products don't quite feel like the packaged products.. ? just a thought...I would like to know more. ![]() ![]() ![]() ![]() | ||
Novice ![]() Posts: 5 |
maybe it's just me, but it seems like Italy knows what he's talking about. ![]() ![]() ![]() ![]() | ||
Amateur Bodybuilder ![]() ![]() Posts: 92 |
Italy seems well knowledgeable of this subject. Maybe spreads some light on the subject of the powdered substances? ![]() ![]() ![]() ![]() | ||
Pro Bodybuilder ![]() ![]() ![]() Posts: 445 |
Interesting...bump for comments from Huck, Cockdzl, et al. ------------------ ![]() ![]() ![]() ![]() | ||
Novice ![]() Posts: 9 |
Hey Thonyct99 You sound like an idiot to me, not Italy. He made the compareson between 200mg from Deca and 200mg from Ttokkyo! I think you should apologise and maybe read better next time! ![]() ![]() ![]() | ||
Guru ![]() ![]() ![]() ![]() ![]() Posts: 3804 |
YOU ARE A <<<<<<<<<<<<<<<<PUKE<<<<<<<<<<<<<< THONYCT99 WHO THE FUCK ARE YOU? ------------------ Lift ![]() ![]() ![]() | ||
Pro Bodybuilder ![]() ![]() ![]() Posts: 521 |
I think Italy is right. You have to wonder why testosterone from Schering is so much better than test from Brovel. There has to be more to it than just simple "underdosing". Maybe that is why the pros grow so well because they have access to high grade material, and alot of what we can get is mexican vet gear. Some of us maybe spinning our wheels because we are shooting solutions that may be only 50% as effective as some of the stuff they are taking. I don't know, just a thought. ![]() ![]() ![]() ![]() | ||
Pro Bodybuilder ![]() ![]() ![]() Posts: 545 |
great read bump ![]() ![]() ![]() ![]() | ||
Cool Novice ![]() ![]() Posts: 48 |
Good stuff, thanks Italy and others... ------------------ You can run but you'll just be tired when I catch you. ![]() ![]() ![]() | ||
Moderator ![]() ![]() ![]() ![]() Posts: 5635 |
Yes I'd have to say i agree with you Italy. ![]() ![]() ![]() ![]() | ||
Elite Bodybuilder ![]() ![]() ![]() Posts: 755 |
Okay, Thanks. ------------------ "Obsession is passion. Use it. Make it your strength." -by Puc ![]() ![]() ![]() ![]() |
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