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  I MUST CLEAR UP SOME MISINFORMATION NOW ABOUT PROGESTERONE RECEPTORS AND NOLVADEX.

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Author Topic:   I MUST CLEAR UP SOME MISINFORMATION NOW ABOUT PROGESTERONE RECEPTORS AND NOLVADEX.
JUICESEEKER

Elite Bodybuilder

Posts: 637
From:
Registered: Feb 2000

posted October 16, 2000 06:52 PM

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SOME PEOPLE ON THE BOARD SAY THAT IF YOU HAVE A PROGERONE INDUCE CASE OF GYNO, THAT NOLVADEX WOULD NOT WORK SINCE IT IS A ANTI-ESTROGEN. I WOULD SAY THAT IS BULLSH@t!
AS YOU READ THIS EXCEPT THAT I COPIED FROM MEDSCAPE "Contemporary endocrine therapy was introduced to the clinic over 25 years ago with the launch of the antiestrogen, tamoxifen, in 1973. Subsequent
research has concentrated on providing additional endocrine methods of depriving tumor cells of estrogen stimulation. Presently, the major endocrine
therapy options for advanced disease include:

1.antiestrogens such as tamoxifen, which is currently the standard adjuvant endocrine treatment in both postmenopausal women and premenopausal
women with estrogen receptor (ER)-positive and/or progesterone receptor (PgR)-positive disease

2.new-generation triazole aromatase inhibitors (eg, anastrozole and letrozole), currently available for use in postmenopausal women in whom disease
has progressed while on tamoxifen or other antiestrogens." YOU WOULD SEE THAT NOLVADEX IS USED FOR BOTH ESTROGEN AND PROGESTERONE RECEPTORS. AND NOLVADEX IS THE STANDARD TREATMENT FOR BOTH RECEPTORS.
SO TAKE ALL THE DECA YOU WANT, BECAUSE NOLVADEX WILL STILL GETTHE JOB DONE!

JUICE.


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Yuckon

Amateur Bodybuilder

Posts: 95
From:
Registered: Mar 2000

posted October 16, 2000 07:22 PM

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bump.........


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Pharm Animal

Elite Bodybuilder

Posts: 611
From:Honolulu, HI
Registered: Aug 2000

posted October 16, 2000 07:31 PM

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FYI, bros...

"anastrozole" is the chemical name for arimidex

------------------
>|===|--
Take care,
P.A.


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Slopain

Guru

Posts: 2495
From:Yo Aunties Pad
Registered: Jan 2000

posted October 16, 2000 07:33 PM

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I know this not to be true, only because my training partner is on 1g of test and with nolvadex he is perfect. But at 200mg of deca per week he got gyno bad, he tried nolva, he tried proviron, but nothing helped. He had to get it cut out.

Of course, Id love to hear more opinions on this. I know its not scientific, but I saw this happen with my own eyes.

Slopain

------------------
- If you want 1 year of prosperity, grow grain. If you want 10 years of prosperity, grow trees. If you want 100 years of prosperity, grow people. -

For a good time click here: Search and Profiles (300Kleens Board)


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The Ranger

Moderator

Posts: 2713
From:
Registered: Feb 2000

posted October 16, 2000 09:15 PM

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There is a vast difference between Nolvadex, and Armidex.

1. Nolvadex is a competive inhibitor of estrogen, simply put, it will compete for the estrogen recepters.

2. Armidex is a non competive inhibitor, simply put, it stops it from ever starting.

Always try and remember that most medical reports are for current use under a prescription, and Doctor Guidence.

There has not, nor will there ver be a long extensive study on the massive dosages and anti-estrogen drugs steroid users use to battle gyno.

And, this study was done on women...not juiced out freaks of nature....Nolvadex will have little, or no effect on Prog. induced gyno...my thoughts on this Bro!!


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macrophage69alpha

Moderator

Posts: 1541
From:San diego, CA
Registered: Jan 2000

posted October 16, 2000 11:37 PM

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incorrect assumptions.......
novaldex is somewhat effective in women who have PR induced anomalies, merely because it blocks ER so that the problem is not exacerbated by ER stimulation. It has no direct effect on PR.

------------------
MP



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DREXX

Elite Bodybuilder

Posts: 922
From:Canada
Registered: May 2000

posted October 16, 2000 11:53 PM

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Interesting!

I always thought that the novaldex would do nothing for progesterone induced gyno.

Macro: Do you think that novaldex will help a little when used with Deca by inhibiting atleast the estrogen part or will it do nothing...

------------------
If it's not hard it's not worth doing...


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barney

Amateur Bodybuilder

Posts: 223
From:down under
Registered: Jun 2000

posted October 16, 2000 11:59 PM

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so Ranger, are u saying that armidex is effective on a deca cycle, inhibiting progetserine gyno?


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HUCKLEBERRY FINNaplex

Guru

Posts: 4218
From:Timbuktu
Registered: Jan 2000

posted October 17, 2000 12:02 AM

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I will tell you from FIRST HAND experience that nolvadex doesn't do jack squat against progestogenic gyno from deca.20mgs/daily of nolvadex will prevent gyno from 750mgs/week of sust for me,but 40MGS of nolva on a 400mgs/week of deca,and I'm ready to be milked.DOES NOT WORK IN THE REAL WORLD.

[This message has been edited by HUCKLEBERRY FINNaplex (edited October 17, 2000).]


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lawnsaver

Amateur Bodybuilder

Posts: 209
From:FL
Registered: Sep 2000

posted October 17, 2000 12:21 AM

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will arimidex work on deca gyno? Or is winny our only hope.


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macrophage69alpha

Moderator

Posts: 1541
From:San diego, CA
Registered: Jan 2000

posted October 17, 2000 01:09 AM

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Deca does not convert to estrogen.
using nolvaldex will NOT help, or its help will be unnoticable in a normal male, unless you are taking Test or other aromatics in which case it will help but generally you will still get GYNO, unless you are only mildy sensitive to the progestenic binding effects of DECA.

BASICALLY it does not help, except in limited situations or to limit the exacerbation by ER stimulation.

Winstrol,ru-486(when dosages can be worked out), and other ANTI-PROGESTINS are the only true method to inhibit/reverse progestin induced GYNO.

------------------
MP



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The Ranger

Moderator

Posts: 2713
From:
Registered: Feb 2000

posted October 17, 2000 09:01 AM

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Nope, Armidex won't help very much....but, it is speculation that Armidex will reduce existing gyno to the point of nullity....It is very good at what is does....up the test, add winny....


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Jeff_rys

Elite Bodybuilder

Posts: 1069
From:The future a 1000 years from now
Registered: Apr 2000

posted October 17, 2000 11:02 AM

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I am with you guys, i also think gyno from Deca is hard to stop. Deca is good for guys not prone to gyno. I would prefer Winny over anything to fight Progesterone. Even if there is no prove how much Winny can do for you.

------------------
Jeff

Don't look back, life is too short


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