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 Anabolic Discussion Board
 Cypionate longer acting than enanthate?
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| Author | Topic: Cypionate longer acting than enanthate? | ||
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Amateur Bodybuilder 
Posts: 99 |
I was reading Musclemag at work today and they had an article ranking the different tests. Whoever wrote it said that cyp had a half life of like 8 days and enanth was like 4. He suggested using cyp every 4th day or enanthate eod. Correct me if I'm wrong (and maybe I am), but doesn't enanthate have a longer half life than cypionate? ------------------     | ||
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Novice 
Posts: 5 |
Some people I know thought that too but I read in Planet Muscle Mag that Cyp has a longer half life. The only difference other than that is that Enanthate has less water retention assocaited with its use but they are more or less similar. | ||
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Cool Novice 
Posts: 34 |
The article is correct. Enanthate has a half life of 4 (Weinbauer, G.F.; Jackwerth, B; et al. Acta Endocrinol. Copenh., 1990, 122, 432-42) and cypionate's is 8 days(Belkien, L.; Schurmeyer, T.; et al. J. Steroid Biochem., 1985, 22, 623-629). [This message has been edited by ontariowrestler (edited October 08, 2000).] | ||
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Elite Bodybuilder 
Posts: 1199 |
That is not true. Cypionate and enanthate are almost identical. The release patterns and halflives might be one days difference. | ||
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Amateur Bodybuilder
Posts: 250 |
The Saint is right! It's all right here on elitefitness, go to: www.elitefitness.com/articles/esters.html In the table of contents click on to #3 ester profiles and conclusion. It states "Athletes commonly hold the belief that cypionate is more powerful than enthanate, although realistically there is little difference between the two". But I suggest to read the whole thing and print it out for future reference. Notice the chemical structures of the two. [This message has been edited by jocko (edited October 07, 2000).] | ||
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Elite Bodybuilder
Posts: 1469 |
saint is right..they are about =..if you have a choice go with the ethan..it is cheaper and real..almost all cypinates are fake or ethanates sold at a higher price | ||
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Amateur Bodybuilder
Posts: 99 |
Thanks for the replies. I have enanthate and had no intentions of obtaining the often fake cypionate. I was just wondering, because the article went against what I had thought about the two esters. ------------------ | ||
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Amateur Bodybuilder
Posts: 55 |
hey don't slander my name LoL My next cycle will have brazilian cyp in it called Deposteron, no more upjohn for upjohn LoL I hope its very good, as I hear Anyone here used it before? | ||
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Cool Novice
Posts: 34 |
I am bumping this as I edited my post to include references showing the article is correct. | ||
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Amateur Bodybuilder
Posts: 116 |
i have always heard that cyp should be taken every 7 days and enanthate should be taken every 10 days. the enanthate ester is in fact longer than cyp. so the half life of enanthate should likewise be longer. this info also comes from personal experience with both and from well educated sources in the gym and elsewhere. | ||
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Cool Novice
Posts: 34 |
What do I have to do to prove that the half-lifes stated in the article are correct? No one here has referenced anything other than personal experience or knowledgeable sources. Don't mean to rant, I am just getting pissed that I I have given two medical references of studies done to calculate the half-lifes of both esters and you still doubt the information. Bill Roberts has written that the half-lifes are 4 and 8 days, but the difference is more likely no more than two days because of different measuring techniques used. http://www.mesomorphosis.com/exclusive/pharmacology/vol02/991213.htm Title Pharmacokinetics and pharmacodynamics of testosterone enanthate and dihydrotestosterone enanthate in non-human primates. Weinbauer GF Institute of Reproductive Medicine, The University, M�unster, FRG.
Abstract The pharmacokinetics and pharmacodynamics of testosterone enanthate and dihydrotestosterone-enanthate were compared in orchidectomized cynomolgus monkeys (Macaca fascicularis) and in intact GnRH agonist-suppressed rhesus monkeys (Macaca mulatta). Following a single im injection of 32.8 mg testosterone enanthate or 32.7 mg dihydrotestosterone-enanthate, i.e. 23.6 mg of pure steroid, in the orchidectomized cynomolgus monkeys, serum testosterone and dihydrotestosterone levels rose to 400 and 800% of baseline, respectively, within 24 h. Androgen levels remained in that range for 3-5 days followed by a continuous decline until baseline values were attained after 4-5 weeks. The areas under the testosterone- and dihydrotestosterone-curves did not differ significantly 2290 +/- 340 (dihydrotestosterone-enanthate) vs 2920 +/- 485 (testosterone-enanthate) suggesting that similar amounts of steroid had been released from the respective ester preparation. Mean half-life estimates of the terminal elimination phase were 4 and 7 days for testosterone-enanthate and dihydrotestosterone-enanthate, respectively. In a second experiment rhesus monkeys received, at 4-weekly intervals, sc implantation of a biodegradable polylactic Eng 90239987 Publication Type JOURNAL ARTICLE 0001-5598 DENMARK 9008 [This message has been edited by ontariowrestler (edited October 09, 2000).] |
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posted October 07, 2000 06:31 PM
olyglycolide rod loaded with the GnRH agonist buserelin. The last injection was given during week 20. GnRH agonist treatment suppressed serum bioactive LH, testosterone and dihydrotestosterone levels, testicular size, sperm production, and seminal carnitine content. The ejaculatory response to electrostimulation and the masturbatory behaviour were abolished. Testosterone or dihydrotestosterone injections at the same doses as above were given in week 10, 14, 17 and 20 of GnRH agonist treatment. Serum testosterone and dihydrotestosterone levels were stimulated 9- and 4-fold, respectively. Mean half-life estimates for testosterone-enanthate and dihydrotestosterone were 5 and 7 days, respectively. Both ester preparations completely restored the ejaculatory response, ejaculate size, masturbatory behaviour, and seminal carnitine levels. In conclusion, androgen substitution with dihydrotestosterone-enanthate, in equivalent doses, is as effective as testosterone-enanthate in restoring reproductive functions in hypogonadal monkeys.