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 Anabolic Discussion Board
 Do any bodybuilders usd Glucagon?
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| Author | Topic: Do any bodybuilders usd Glucagon? | ||
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Elite Bodybuilder 
Posts: 715 |
I don't know the brand name or anything, hell, it's probably counterproductive. Anyway, based on my minimal amount of biochem background, it seems to me that it could be used during the last week of a cycle, for competitors maybe, to promote fatty acid oxidation by hydrolizing triacylglycerols. The only problem that I see is that it also inhibits glycogen biosynthesis (it is basically the opposite of insulin). Is this what glucaphage is?     | ||
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Cool Novice 
Posts: 21 |
bump | ||
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Pro Bodybuilder 
Posts: 330 |
Noooo, Glucagon is a catabolic hormone produced by the body, when blood sugar gets low from not consuming carbohydrates. The function of this hormone is to establish consistant blood sugar levels by converting stored liver and muscle glycogen to glucose for use by the brain (first and foremost) and the rest of the body. It is, relatively speaking the exact opposite of insulin, (which is an anabolic hormone), thus when insulin levels are high (from ingesting carbs), glucagon levels are low, and when lnsulin levels are low, (no carbs), glucagon is high, (ex. times of fasting and/or on a ketogenic diet). Now, glucophage is an insulin antagonist used mostly by diabetics to control blood sugar. The mode of action of glucagon is to increase insulin sensitivity of muscle and other tissues (good), which in turn lowers insulin secretion, because you don't need as much insulin to transport nutrients into your cells, if your cells are very sensitive to insulin. I have used glucophage and I recomend it if you can find it especiall when dieting. Hope this helps, now I'm tired!!! | ||
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Amateur Bodybuilder 
Posts: 242 |
I'm going to bump this 'cause this hasn't been asked 20 times in the last 20 days and I'd like to see some more info on it... ------------------ | ||
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Amateur Bodybuilder
Posts: 299 |
You mean Glucophage? Right! cut and past from anabolex Glucophage - 850 mg. tablets - 40 per box. Glucophage is a brand name for metformin which is an oral hypoglycemic drug. Glucophage was made to be used to control adult onset diabetes. This drug is will increase the body's ability to transport glucose into the muscle cells much better by increasing insulin sensitivity. This substance will also inhibit the body's formation of sugar by the liver whereby lowering insulin secretion in the body. This substance is very similar to phenformin, that is also an oral hypoglycemic except that phenformin is considered the harsher of the two compounds. Phenformin is considered to be from 5 - 10 times stronger than Glucophage at what it does for the body on a mg. per mg. comparison. Glucophage has signifigantly less side effects than phenformin has as well. The chance for an overdose causing hypoglycemia with the use of Glucophage is dose related whereas you almost have to take a lethal dose. It is common knowledge that Glucophage will increase insulin sensitivity as well. As far as bodybuilders are concerned, this product is used as an oral form of insulin. It will cause greater glycogen supercompensation during carb-ups as well as lowering blood glucose for those that are using the BodyOpus or Atkins diet to induce ketosis more easily. Common side effects of Glucophage are a metallic taste in the mouth, nausea, and vomiting. This will become on the next big drugs used by professional bodybuilders in the coming years for its ability as a repartitioning agent and blood glucose disposal agent. Effective Dose: 1,700 mg. per day in divided doses. You have to take this with meals and with water to avoid stomach upset. Street Price: Glucophage is very expensive in the US so I would anticipate a rather steep street price as well. Probably about $3 per pill. Stacking Info: This compound is commonly taken with Creatine in order to help shuttle the creatine into the muscles more effectively since this product increases insulin sensitivity. Used by permission from Champy's Anabolic/Androgenic Steroid Profiles site
Common side effects of Glucophage are a metallic taste in the mouth, nausea, and vomiting. This will become on the next big drugs used by professional bodybuilders in the coming years for its ability as a repartitioning agent and blood glucose disposal agent. Effective Dose: 1,700 mg. per day in divided doses.You have to take this with meals and with water to avoid stomach upset. ------------------ | ||
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Elite Bodybuilder
Posts: 715 |
So then, the body uses glucagon to convert glycogen stores to fuel IN ADDITION to the fuels derived from acetyl-CoA such as B-Hydroxy Butyrate and Acetoacetate? Does the body use all three of these fuel sources when on diets such as Bodyopus? Is glucagon catabolic to just glycogen and fatty acids, or also amino acids? | ||
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Pro Bodybuilder
Posts: 330 |
It isn't catabolic to the muscles persay, muscle catabolism is most commonly due to glucose shortage at the brain, due to lacking amounts of carbohydrates while dieting. The brain requires 100g of glucose a day to function. If the body has not shifted into ketosis, thereby lowering the brain's needs for glucose, and the 100g of glucose is not being supplied in a steady stream throught out the day the body will scavange muscle protein for glucose. When in ketosis the body and brain rely on Ketones for the major fuel source for the body. The glucose needed for the brain (approx. 45g when in ketosis) is supplied by the large amount of dietary protein consumed on this type of diet,(approx. 50% of protein is converted into glucose for the brain during ketosis). | ||
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Amateur Bodybuilder
Posts: 72 |
hey guys...I would like to know if anyone can brakdown this information to a simpler level and tell me how this could help me in a contest diet while using t3, clen, and xenadrine,... thanks  ------------------ | ||
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Novice 
Posts: 7 |
Well I do not know from experience, but from what I have been told. Glucaphage is to Insulin waht Andro is to Test, basically a waste. But I agree with Columbowieser (spelling) please explain it to us like the dumb-jocks we are suppose to be. It is nice to hear all scientific jargon but bottom line we need some straighgt foward info we can use. | ||
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Pro Bodybuilder
Posts: 523 |
Basically glucogon is the exact opposite of insulin. Insulin builds glycogen (glucose polymers) in the liver and muscles for storage. Glucogon does the opposite....it quickly puts the glucose back into the bloodstream. After reading through research for years, there is nothing more beautiful than something concise and simple. |
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posted October 07, 2000 02:03 PM