As bodybuilders, weight lifters, competitive athletes, and intellectuals none of us can function as human beings without the chemical processes of the body. But, what in the hell is this process of �oxidative phosphorylation� (OP)? What exactly are �uncouplers� and how do we lose weight from �thermogenic � compounds?

Most of you who know me are aware that I am a stickler for simplicity, my lack of formal training within the field of chemistry, biochemistry, and endocrinology forces me to seek the simplest comprehensible answer. Lets tackle this process of OP and it�s exact implication to the bodybuilder.

Of foremost importance is to place this concept into perspective. OP is simply the term used to describe the formation of �Adenosine Triphosphate� as a result of transferring electrons to oxygen. Were dealing with the creation of �chemical energy�.

To further clarify this issue, I want you to think of our modern conception of the internal combustion engine. To this engine we now affix a drive shaft, axles, and tires. We now have energy in motion. This process is analogous to our own production of chemical energy within our system. Our Internal Combustion engine would be the mitochondria found within the cell. ATP�S presence at the cellular level is the fuel by which we realize our daily physical activity. Thus, our ability to train is realized.

Oxidative uncoupling is the process by which the formation of ATP can be inhibited. Let us fall back to our example of the engine. If we have the same engine suspended on a stand. Absent in this situation are the aforementioned parts needed for physical locomotion. Drive shaft, axles, and tires are not present. The agent by which energy is produced has not changed. The cellular engine (mitochondria) hasn�t changed, were still witnessing the creation and transference of energy we just no longer see it being done chemically. Instead, we see it the form of kinetic energy.

The energy that is produced is released in the form of heat. Since oxidative uncouplers increase heat production, they are sometimes referred to as �thermogenic agents�. Oxidative uncouplers such as DNP, MBEBP, Sodium Usinate, and Leptin all work in this fashion. To effectively impede the collection of cellular ATP, and in it�s stead release it in the form of heat.

This increased body temperature promotes an increased rate of lipolysis. In conjunction with time, this increased rate of lipolysis contributes to the rapid loss of adipos tissue bodybuilders realize in precontest training.

What have I left out? Please feel free to contribute more in depth information on this issue. Take note, that these products pose a significant danger to the unskilled user.
Therefore, I take little interest in their use. I am not about to ingest a chemical originally designed by the French to be used as a primary ingredient in explosive material. This however, doesn't detract from these agent's fasinating properties. Ohh, as a side note, science first became aware of DNP and its effects in the early 19th century when French munition workers first became exposed to it within the confines of their munition factory's, but I digress.
This is why research on leptin, the "obesity gene" has been so promising. I believe in the next 4-5 years science will have answered some of the vexing questions about Leptin resistance and its application as perhaps the safest oxidative uncoupler of them all. I�ll post information on this, as I find it.

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215LBS of Twisted Steel and Pure Sex Appeal!

Bjaarki

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"'Til the weard of the world, stands, unforgotten,
high under Heaven, the hero's name." - Hrolf Krakki's Saga (Iceland)

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