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  Trophobolene

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Author Topic:   Trophobolene
Twisted_Steel

Elite Bodybuilder

Posts: 932
From: South Carolina
Registered: Apr 2000

posted September 08, 2000 10:09 PM

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Trophobolene by Theramex monaco-france ..

Composition:
1ml contains
Oestradiol Propionicotinate (p.n.o) 1.3mg
19 norandrostenolone undecanoate (u.n.a) 80mg
17alpha hydroxyprogesterone heptanoate 80mg
benzyl benzoate 45% (q.s) 1ml

Ok, I have exahusted my avenues, perhaps someone would care to enlighten me on the chemical properties behind this anabolic? I ran across a Duchaine article which briefly mention that this was Frenchmen Serge Nubret's favorite compound. FYI, Serge was the one who placed second behind Arnold last Legitamet olympia win. The black man who beat out Louie for the second spot in Pumping Iron.

Obviously the terms "estradiol" and "progesterone" are involved, so that further peeks my curiosity


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215LBS of Twisted Steel and Pure Sex Appeal!

[This message has been edited by Twisted_Steel (edited September 08, 2000).]


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@LRG

Pro Bodybuilder

Posts: 455
From:
Registered: May 2000

posted September 08, 2000 11:00 PM

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sorry bro, but ill bump for you.

im@LRG


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liltank

Amateur Bodybuilder

Posts: 101
From:
Registered: Aug 2000

posted September 08, 2000 11:40 PM

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Yes i have heard he used that as well. I believe that low levels of estrogen will promote growth when mixed with higher levels of testosterone,Again I am not 100 % on this but have done some reading and talked to an old friend of mine..hope this helps..

tank


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E2

Moderator

Posts: 3918
From:VALHALLA
Registered: Oct 1999

posted September 09, 2000 12:51 AM

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Just so you know bro, i'm looking into this, but i'm in there oestradiol (E2) so it must make you grow!! heh heh


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E2

Moderator

Posts: 3918
From:VALHALLA
Registered: Oct 1999

posted September 09, 2000 12:56 AM

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Anyone speak swedish, i'm sure there are a few on here

TROPHOBOLENE.
Varje milliliter inneh�ller Hydroxy Progesteron Heptanoate 80 mg och
Norandrostenolone Undecanoate 80 mg. Detta preparat �r tillg�ngligt i en version som �r anpassad f�r s�v�l m�nniskor som i en veterin�nersion. Jag har h�rt rykten om att n�gra europeiska kroppsbyggare anv�nder detta preparat, men det tycks inte vara ett effektivt preparat f�r idrottsm�n. Det beror f�rst och fr�mst p� att det inneh�ller progesteron, ett kvinnligt hormon, som �r tillsatt f�r att neds�tta
maskuliniseringen orsakad av androgenerna i denna medicin.


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E2

Moderator

Posts: 3918
From:VALHALLA
Registered: Oct 1999

posted September 09, 2000 01:06 AM

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Ok so what i've found out is that the oestradiol is a very strong oestrogen.
oestrogen
A generic term for oestrus producing steroid compounds, the female sex hormones. In humans, oestrogen is formed in the ovary, possibly the adrenal cortex, the testis and the foetoplacental unit, it has various functions in both sexes. It is responsible for the development of the female secondary sex characteristics and during the menstrual cycle it acts on the female genitalia to produce an environment suitable for the fertilization, implantation and nutrition of the early embryo. Oestrogen is used in oral contraceptives and as a palliative in cancer of the breast after menopause and cancer of the prostate, other uses include the relief of the discomforts of menopause, inhibition of lactation and treatment of osteoporosis, threatened abortion and various functional ovarian disorders.


Ok granted i think we all knew that, now the 17 alhpa hydroxyprogesteron heptanoate is a very strong antagonist to oestrogens. So putting them in the same compound doesn't make too much sense to me. The 17a hydrop will bind to the oestrogen receptor and nullify the effects of the oestrogen.

As for the norandrostenolone udnecanoate all i could find for now is this http://www2.biam2.org/www/Sub1235.html

and this
http://www2.biam2.org/www/Sub3005.html

which is the norandrostenolone decanoate, which is just nandrolone decanoate.

That's my guess at 1am.


[This message has been edited by E2 (edited September 09, 2000).]


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mokhtarsayed

Amateur Bodybuilder

Posts: 226
From:
Registered: May 2000

posted September 09, 2000 06:36 AM

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I can't really figure out the pharmacology of trophobolene. But the bodybuilders where I live just love it. Also women bb use it alot here. It seems to cause less masculinity in women.

------------------

_______________________
Mokhtar


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moondog

Amateur Bodybuilder

Posts: 162
From:
Registered: Jun 2000

posted September 09, 2000 07:08 AM

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If you'd like to send me some, I'd be happy to try it out on my little brother mikey.


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mokhtarsayed

Amateur Bodybuilder

Posts: 226
From:
Registered: May 2000

posted September 09, 2000 07:12 AM

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No, but you can send me mikey and I'll try it on him and tell u what happens. Hope he has good genes.


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moondog

Amateur Bodybuilder

Posts: 162
From:
Registered: Jun 2000

posted September 09, 2000 07:34 AM

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You can have him. I was just kidding, making a reference to the old Life cereal commercial.


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COnCReTE_MAsS

Amateur Bodybuilder

Posts: 169
From:Egypt
Registered: Jul 2000

posted September 09, 2000 09:30 AM

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PROPERTIES:
each of its 3 components has its specific contribution
p.n.o is an original vitamin-steroid molecule , its responsible for the tissue trophic activity of the drug and its powerful bone tropism.
U.N.A is the anabolic and anti catabolic agent wich brings back, and at the same time saves the protien and calcium used for the building of living tissue
H.O.P is the sodium ddepletion factor and the catalyst for the interctions of the steroids

trophobolene has a distinct effect on cellular proliferation,vascularisation and tissue protection,thus trophobolene has an intensive vascular,conjuctive and epithlial tropism.
trophobolene is able to protectthe vascular endothelium and avoid the pseudo-inflammatory reaction of collagen in the intima of the arteries.
trophobolene is effective in ischaemia , atrophic or inert bone,wethere due to disease , trauma or corticotherapy

INDICATIONS:
-A therosclerosis , its complications and sequelae.
-diabetes mellitus & vasculo-degenerative complications
-nutritional manifestations connected with neuropathy
-delayed union of bone grafts and fractures
-neurosurgery , nutritional complications, neurovascular sequelae
-diffuse or localised decalification.
-tropho metabolic osteochondrosis


CONTRA INDICATIONS:
-pregnancy
-carcinoma of breast or prostate.
- infants under 18 months

WARNING:
trophobolene may cause virtilism in women "deep voice,increased libido,menstrual disturbance"
strict medical supervision and observance of the dosage in young women may avoid these effects .


CONCRETE MASS,,


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Twisted_Steel

Elite Bodybuilder

Posts: 932
From: South Carolina
Registered: Apr 2000

posted September 09, 2000 09:36 AM

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I called out some of the big guns on this one, waiting for their response. Wheres Cockdezl when one needs him. Concrete_Mass's post was helpful, but It really didnt give me an idea of this drugs effectivness as a muscle building agent.

Thanks for your input E2, Ill be adding my results to this thread once their e-mailed to me so to satisfy our mutual curiosity.

------------------
215LBS of Twisted Steel and Pure Sex Appeal!


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micke

Pro Bodybuilder

Posts: 582
From:sweden
Registered: May 2000

posted September 09, 2000 10:07 AM

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E2 you are verry good at swedish or is it your swedish girlfriend who write this! lol

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bigswed a man build of test hard as steel....:)


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SUST-MAN

Amateur Bodybuilder

Posts: 255
From:CRESSKILL, NJ
Registered: Jul 2000

posted September 09, 2000 05:19 PM

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Bump...

------------------
Your not a fish...your a MAN! HOMO-ERECTUS!


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Twisted_Steel

Elite Bodybuilder

Posts: 932
From: South Carolina
Registered: Apr 2000

posted September 09, 2000 05:31 PM

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Jumbo Polumbo pulls through in the clutch once more. Here is a copy of our e-mail exchange. Its not the final word yet, but his input goes a Looooong way.


TROPHOBOLEN

Expression de la composition : par unit� de prise, soit pour :
Volume : 1 ml

Principes actifs

ESTRAPRONICATE 1.30 mg
NANDROLONE UNDECANOATE 80 mg
NANDROLONE UNDECANOATE
HYDROXYPROGESTERONE HEPTANOATE 80 mg
http://www2.biam2.org/www/Spe9203.html


David, it was good to see you up on stage at the USA's. Second, I need you
to share with me your years of experience and enlighten me on the
bodybuilding pharmacological uses of this particular drug. My background
information is rather sketchy at the moment. I read that this was the
preferred compound of Sege Nubret from france in the 70's. My concerns
obviously, is seeing the term "estra" and "progesterone" being incoorporated
into this compound. Has chemsitry rendered their negatively associated sides
inert ? In other words, Is this a compound worth investing in and using? >>

As you so wisely noted, TROPHOBELENE, in addition to containing the
19-NORTESTOSTERONE derivative, NANDROLONE UNDECANOATE, also contains estrogen
and progesterone (it is wise to always read the list of active ingredients on
the box or pamphlet insert). Assuminmg that you are looking to GROW MUSCLE
and look hard, i would not suggest using or investing in this compound. It
would make you extremely bloated and you would get a nasty case of
gynecomastia.

DAVE

------------------
215LBS of Twisted Steel and Pure Sex Appeal!


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cockdezl

Pro Bodybuilder

Posts: 339
From:
Registered: 2000

posted September 09, 2000 05:34 PM

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Trophobolene is a strange drug combination and few have any experience with it. I, also, read the story concerning Serge Nubret's use of it, from some members of misc.fitness.weights.

CONCRETE's post was useful to determine its medical use. It seems to be used as an anabolic, cardioprotectant, and/or osteogenic agent. The estradiol is for cardioprotection, probably through blood lipid modification. The combo of nandrolone and estradiol are for bone modification, while the progesterone is to offset the sodium retention that occurs with use of the other two agents.

Duchaine did speculate about its use, and stated that it maybe a useful precontest drug. One, progesterone increases lipolysis and free fatty acid levels, which causes a slight insulin insensitivity. This is NOT useful normally, but when dieting, it helps reduce muscle protein catabolism and favors fat utilization. Also, progesterone is ketogenic and thermogenic; Duchaine commented on this latter effect stating it was due to an effect on Uncoupling Protein 2, but I have not been able to confirm this. Progesterone, also, decreases sodium reuptake by the kidneys, so there is a diuretic effect by it. If it can overcome the effects of estradiol and nandrolone is beyond me, but this seems to be what CONCRETE has shown in his post.

One would assume a high risk of gyno with a estrogen/progestin combo, but I have heard of people state that they never experienced this with Trophobolene.


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Twisted_Steel

Elite Bodybuilder

Posts: 932
From: South Carolina
Registered: Apr 2000

posted September 09, 2000 06:48 PM

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Dezl, thank you. Hmm, the obvious need for an aromatase inhibitor is apparant. If one were to incoorporate, Arimidex daily, potentially the undesireable sides could be effectivly negated? One would still benefit from the increased state of lipolysis, yes?


------------------
215LBS of Twisted Steel and Pure Sex Appeal!

[This message has been edited by Twisted_Steel (edited September 09, 2000).]


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HUCKLEBERRY FINNaplex

Elite Bodybuilder

Posts: 1161
From:Timbuktu
Registered: Aug 2000

posted September 09, 2000 08:28 PM

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I'm going to bump this one back up as it has some incredible info.Cockdezl,any more input you could offer regarding TS'S last question?


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cockdezl

Pro Bodybuilder

Posts: 339
From:
Registered: 2000

posted September 11, 2000 12:05 AM

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TWISTED, the use of a aromatase inhibitor would be useless with this drug, since there is nothing to inhibit. The estrogen is already present as estradiol propionicotinate (1.3mg) and the amount of conversion of nandrolone undecanoate to estrogen is low. An estrogen blocker, such as Clomid or Nolvadex would be more appropriate. But this still leaves two progestagenic drugs. You think Deca gyno is a problem, add in real progesterone. This is a weird drug, indeed.


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