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  Confused on Androgenic vs. Anabolic

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Author Topic:   Confused on Androgenic vs. Anabolic
Zeke_B

Amateur Bodybuilder

Posts: 75
From:
Registered: Jun 2000

posted September 05, 2000 12:49 AM

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Guys,

I know what androgenic and anabolic mean, but I'm a little confused. There seems to be somewhat of a consensus that an androgenic drug is a good thing. I would think that an androgenic effect would be caused by a substance (or something the substance turns into) binding with something other than skeletal muscles. Other than some short-term strength gains and increased libido, I would think that it wouldn't be desirable for a drug to have an androgenic effect. Judging by what I have seen, androgenic drugs happen to be more anabolic as well, but this isn't what I'm talking about. Without clinical studies, people pretty much go on things like feel, strength gain, and weight gain. If we're talking short term here, this would cause a bigtime preference for highly androgenic substances, despite the fact that these effects are for the most part side effects of the real goal which is muscle hypertrophy. Please give me some info. and opinions. Should we all be using deca instead of test? I wish even half of the amount of research being done on crappy prohormone supplements was being done on honest-to-goodness roids, although most of the prohormone research is funded by supplement companies and thus is crap!

zeke_b

[This message has been edited by Zeke_B (edited September 05, 2000).]


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cockdezl

Pro Bodybuilder

Posts: 332
From:
Registered: 2000

posted September 05, 2000 03:17 AM

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ZEKE, interesting post. DHT binds to all the AR's just like test, it just elicits a different signal. We know what DHT does and for the most part it ain't all that. There are some beneficial responses, like libido and ER blocking, but it is responsible for our prostate turning into an orange later in life.
Purely androgenic drugs, like mibolorone and fluoxymesterone, don't really do anything, but cause aggression and CNS stimulation, so it seems that a pure anabolic would be desirable. The best examples of mostly anabolic drugs are stanazolol and oxandrolone. Most think that these are weak in their ability to cause muscle gains, and that they are reserved for pre-contest, but I think we really havent used them at high enough doses to see comparable results. Many take a gram a week of test, but few have ever tried a gram of Winny a week. Since these are orally active, there is the possibility of hepatic dysfunction, so one must be wary.
Another problem with comparing the high androgens with the high anabolics is aromatization. Test aromatizes and the estrogen increase increases insulin, GH and IGF-1 levels, which all contribute to the greater effects that are seen with these drugs. Non-aromatizing drugs have been shown to poorly increase IGF levels. Some have complained about lower gains using anti-estrogens, so when comparing aromatizing with non-aromatizing drugs, you must take into account that you are not getting just an androgenic response.


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Zeke_B

Amateur Bodybuilder

Posts: 75
From:
Registered: Jun 2000

posted September 05, 2000 10:27 PM

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Excellent response cockdezl. Bump this back up to the top...I wan't to hear more


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