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 Anabolic Discussion Board
 Receptor UPGRADE
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| Author | Topic: Receptor UPGRADE | ||
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Cool Novice 
Posts: 46 |
From MMI uncensored: When you juice, you inevitably get some estrogen from aromatization. This isn't all bad because estrogen causes the release of IGF-1, and this causes the incorporation of little things called satellite cells into your muscles. Satellite cells aren't just DNA, they also bring with them androgen receptors. In essence, the IGF-1 (as released from your liver because of aromatization of the steroids) causes an increase in androgen receptor numbers in your muscles. All of a sudden you're more responsive to the juice, but of course, catabolism catches up to match this chance for new growth. On the upside, on your next cycle you will notice that gaining back the 20 or so pounds you lost after you came off your last cycle will be a cinch because all those androgen receptors tend to hang around for awhile. Previous juicers, even if they've been off for years, will always look bigger and harder than guys who have never juiced at all. That's just the way it is. Like it or lump it.
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Amateur Bodybuilder 
Posts: 179 |
good info, bumP!! | ||
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Moderator 
Posts: 3818 |
That is an interesting theory. ------------------ http://2thick.elitefitness.com | ||
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Cool Novice
Posts: 45 |
T-MAN-X That sounds about right. If there was such a thing as receptor down regulation then how come the pro's keep getting bigger and bigger every year. i.e. most people will agree that the pro's are on steroids year round. Now if this is so and their receptors shut down after 5 or 6 weeks then how the hell do they keep getting bigger. Also have you ever noticed when an amateur turns pro or gets a supplement contract they suddenly gain about 20 lb's of muscle almost over night? How would this be possible if their receptors were f****d. Maybe it's really due to all the free whey protein and other supplements that come with their contract - Bollocks. | ||
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Amateur Bodybuilder
Posts: 294 |
Why am I not surprised. A while back I posted something similiar (estrogen and HCG). Of course, the information got cannibalize. ------------------ | ||
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Amateur Bodybuilder
Posts: 141 |
Good post bro, but if the androgen receptors are still around, which they are, then you would have to take a larger dosage to break the plateau. Doing the same dosages would just bring you basically where you were the previous time? What do you guys think? | ||
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Amateur Bodybuilder
Posts: 281 |
so are you saying that we have now more receptors during our cycle because we made more satellite cells and this is why we need more AS ? | ||
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Elite Bodybuilder 
Posts: 854 |
GEEESUS, receptors dont SHUT DOWN, were not talkin about no vacancy signs at your local RAMADA. Good lord I have never seen such an unreal amount of confusion over a relativly simple concept. Receptors cease being as "efficient" over time. This is a phenomenon found within nature, a continuing stiumulous ceases over time to produce and equally viable response. This is over come by, INCREASING the stimuli, in this case, MORE ANDROGENS, or the complete cessetion of the stimuli. Yes, professionals stay year around, buuuut they dont bomb their bodies with heavy androgens year around, even their might genetic propensity towards growth has limits. This is why they transition to mild anabolics to BEGIN a measure of receptor down regulation so that when the time comes to reinsitute the androgens the their upcoming cycle will hopefully yield the results of the last one. ------------------ | ||
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Pro Bodybuilder 
Posts: 327 |
TWISTED, this is getting fucking ridiculous. You have no fucking clue as to what you talking about, yet you rave like you do. Maybe some of the newbies or less read members here listen to you, but I have already shown that you don't know a damn thing concerning this and many other concepts of physiology. This is a major topic of debate, both in this forum and even the scientific community, but yet YOU know the fucking answer. You have yet to give up one piece of reference to any of your claims. "GEEESUS, receptors dont SHUT DOWN, were not talkin about no vacancy signs at your local RAMADA." They don't? Then what is BARK which is concerned with the beta-adrenergic receptor? Since you are a man of better wording than I, then you should know that this phrase "shut down", is simply semantics. Receptors can "shut down" activity, through numerous processes, unfortunately the steroidal superfamily of receptors are still not well understood. "Good lord I have never seen such an unreal amount of confusion over a relativly simple concept." I have never seen a man of little understanding, argue like he knows the answer. |
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posted September 04, 2000 02:24 AM